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Incidence of aerobactin production in Gram-negative hospital isolates [PDF]

FEMS Microbiology Letters, 1987
The production of aerobactin was studied in 943 clinical isolates of 14 different Gram-negative genera. Aerobactin-producing strains were isolated in all the genera of Enterobacteriaceae tested, whereas no aerobactin-producing strains were found in the non-enterobacterial genera (Aeromonas, Pseudomonas, Acinetobacter).
JOSÉ L Martinez, F Baquero, Baquero F
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Aerobactin production by enterotoxigenic Escherichia coli of porcine intestine

Veterinary Microbiology, 1995
Of 135 strains of Escherichia coli from the intestines of healthy and diseased piglets screened, 16 (12%) were positive in a bioassay for aerobactin production. Of these, 15 also carried genetic determinants for heat stable or heat labile enterotoxins.
Susana Suarez, Peter H Williams, Peter H Williams   +2 more
exaly   +3 more sources

Aerobactin production as a virulence factor: A reevaluation

European Journal of Clinical Microbiology & Infectious Diseases, 1988
Iron starvation is one of the major barriers that virulent bacteria must overcome in order to proliferate in the host. Virtually all microorganisms possess high affinity iron (III) transport systems mediated by low molecular weight iron specific chelators called siderophores, the synthesis of which is activated under iron-limiting conditions ...
de Lorenzo V, Martinez JL
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Structural and functional delineation of aerobactin biosynthesis in hypervirulent Klebsiella pneumoniae [PDF]

Journal of Biological Chemistry, 2018
Aerobactin, a citryl-hydroxamate siderophore, is produced by a number of pathogenic Gram-negative bacteria to aid in iron assimilation. Interest in this well-known siderophore was reignited by recent investigations suggesting that it plays a key role in mediating the enhanced virulence of a hypervirulent pathotype of Klebsiella pneumoniae (hvKP).
Daniel C Bailey, Matthew R Rice, Lisa S Mydy   +2 more
exaly   +3 more sources

Aerobactin-mediated utilization of transferrin iron

Biochemistry, 1982
Aerobactin and enterobactin, hydroxamate- and catechol-type siderophores, respectively, were found capable of removing iron (III) from transferrin in buffered solution. Although under these conditions aerobactin displaced the iron much more slowly than did enterobactin, the rate for the former could be accelerated by addition of pyrophosphate as ...
K, Konopka, A, Bindereif, J B, Neilands
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Identification of the siderophores fromVibrio hollisaeandVibrio mimicusas aerobactin [PDF]

FEMS Microbiology Letters, 1994
Noriyuki Okujo, Shigeo Yamamoto, Yamamoto Shigeo   +2 more
exaly   +2 more sources

Genetic and biochemical characterization of the aerobactin synthesis operon on pColV

Molecular and General Genetics MGG, 1984
Certain ColV plasmids of Escherichia coli contain genes that specify functions for the acquisition of iron(III) via aerobactin. The locus for aerobactin synthesis of pColV-K311 was cloned into pBR322. Mutagenesis with the transposon Tn1000, and the generation of deletions with restriction enzymes resulted in multicopy plasmids which complemented pColV ...
R, Gross, F, Engelbrecht, V, Braun
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IS1-mediated mobility of the aerobactin system of pColV-K30 in Escherichia coli

Molecular Genetics and Genomics, 1988
Genes determining the high affinity iron transport system mediated by the siderophore aerobactin are flanked in the enterobacterial plasmid pColV-K30 by inverted repeats of IS1 sequences, suggesting that the aerobactin genes are part of a transposon.
VÍCTOR de Lorenzo, J B Neilands, Neilands J B   +2 more
exaly   +3 more sources

Aerobactin production by a planktonic marine Vibrio sp

Limnology and Oceanography, 1993
Production of siderophores by marine bacteria could potentially contribute to metal complexation by organic compounds in seawater. Direct isolation of planktonic marine bacteria on siderophore indicator plates showed that siderophore producers are present.
Margo G. Haygood, Pamela D. Holt, Alison Butler   +2 more
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Deletion mapping of the aerobactin gene complex of plasmid CoIV

Inorganica Chimica Acta, 1983
With the possible exception of certain strains of lactic acid bacteria, iron is known to be an essential element for all species of microbes and for all higher organisms. Within the cell, iron protein catalysts participate in some of the reactions most fundamental to life, including aerobic and anaerobic energy metabolism, nitrogen fixation ...
Albrecht Bindereif, Peter E. Thorsness, J.B. Neilands   +2 more
openaire   +1 more source