Results 91 to 100 of about 339,203 (181)

Aerobic glycolysis promotes tumor immune evasion by hexokinase2-mediated phosphorylation of IκBα.

open access: yesCell Metabolism, 2022
Dong Guo   +15 more
semanticscholar   +1 more source

Quantitative Analysis of the Effective Functional Structure in Yeast Glycolysis [PDF]

open access: yesarXiv, 2010
Yeast glycolysis is considered the prototype of dissipative biochemical oscillators. In cellular conditions, under sinusoidal source of glucose, the activity of glycolytic enzymes can display either periodic, quasiperiodic or chaotic behavior. In order to quantify the functional connectivity for the glycolytic enzymes in dissipative conditions we ...
arxiv  

Selective advantage of aerobic glycolysis over oxidative phosphorylation [PDF]

open access: yesarXiv
The utilization of glycolysis in aerobic conditions have been a subject of debate for more than a century. A hypothesis supported by previous data is that glycolysis has a higher rate of ATP production per protein mass and per occupied volume than oxidative phosphorylation (OxPhos).
arxiv  

Early TCR Signaling Induces Rapid Aerobic Glycolysis Enabling Distinct Acute T Cell Effector Functions

open access: yesCell Reports, 2018
Summary: To fulfill bioenergetic demands of activation, T cells perform aerobic glycolysis, a process common to highly proliferative cells in which glucose is fermented into lactate rather than oxidized in mitochondria. However, the signaling events that
Ashley V. Menk   +10 more
doaj   +1 more source

Self-organization and fractality created by gluconeogenesis in the metabolic process [PDF]

open access: yesChaotic Modeling and Simulation, 2, pp.113-127 (2016), 2017
Within a mathematical model, the process of interaction of the metabolic processes such as glycolysis and gluconeogenesis is studied. As a result of the running of two opposite processes in a cell, the conditions for their interaction and the self-organization in a single dissipative system are created.
arxiv  

4-Octyl itaconate inhibits aerobic glycolysis by targeting GAPDH to exert anti-inflammatory effects

open access: yesNature Communications, 2019
Activated macrophages switch from oxidative phosphorylation to aerobic glycolysis, similar to the Warburg effect, presenting a potential therapeutic target in inflammatory disease.
Shanting Liao   +5 more
semanticscholar   +1 more source

Therapeutic targeting of circ‐CUX1/EWSR1/MAZ axis inhibits glycolysis and neuroblastoma progression

open access: yesEMBO Molecular Medicine, 2019
Aerobic glycolysis is a hallmark of metabolic reprogramming in tumor progression. However, the mechanisms regulating glycolytic gene expression remain elusive in neuroblastoma (NB), the most common extracranial malignancy in childhood.
Huanhuan Li   +14 more
doaj   +1 more source

Saturation of the mitochondrial NADH shuttles drives aerobic glycolysis in proliferating cells.

open access: yesMolecules and Cells, 2022
Yahui Wang   +7 more
semanticscholar   +1 more source

Numerical simulation of growth of Escherichia coli in unsaturated porous media [PDF]

open access: yesarXiv, 2014
A model for the aerobic and anaerobic growth of Escherichia coli (HB101 K12 pGLO) depending on the concentration of oxygen and DOC as substrate has been developed based on laboratory batch experiments. Using inverse modelling to obtain optimal sets of parameters, it could be shown that a model based on a modified double Contois kinetic can predict cell
arxiv  

Tumor cells switch to mitochondrial oxidative phosphorylation under radiation via mTOR-mediated hexokinase II inhibition--a Warburg-reversing effect.

open access: yesPLoS ONE, 2015
A unique feature of cancer cells is to convert glucose into lactate to produce cellular energy, even under the presence of oxygen. Called aerobic glycolysis [The Warburg Effect] it has been extensively studied and the concept of aerobic glycolysis in ...
Chung-Ling Lu   +5 more
doaj   +1 more source

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