Results 41 to 50 of about 423,566 (251)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
DEVELOPING INSTRUMENT TO MEASURE RELIGIOSITY AND OTHER AFFECTIVE DOMAIN IN TEACHING AND LEARNING MATHEMATICS [PDF]
, 2015 Mathematics is a universal knowledge that useful for human life. Competence in mathematics learning is not only focused on the cognitive domain, but also on affective domain.
Dewi, Mardhiyana, Jailani, .
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
AFFECTIVE DOMAIN DEVELOPMENT: REALITY AND EXPECTATION [PDF]
Pengembangan Ranah Afektif: Kenyataan dan Harapan. Pendidik masa kini mendambakan perhatian yang seimbang terhadap pengembangan ranah kognitif, psikomotorik dan afektif dalam mendidik generasi muda.
Sugirin, Ph.D.
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FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
EEG-Based Emotion Recognition Using Regularized Graph Neural Networks
, 2020 Electroencephalography (EEG) measures the neuronal activities in different brain regions via electrodes. Many existing studies on EEG-based emotion recognition do not fully exploit the topology of EEG channels.
Miao, Chunyan, Wang, Di, Zhong, Peixiang
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Measuring Wellbeing in the SOEP [PDF]
I define wellbeing as preference realization. Wellbeing can be measured with affective (the amount of pleasant versus unpleasant experiences) and cognitive (satisfaction with life in general and life domains) measures.
Ulrich Schimmack
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From Affective Science to Psychiatric Disorder: Ontology as Semantic Bridge [PDF]
, 2018 Advances in emotion and affective science have yet to translate routinely into psychiatric research and practice. This is unfortunate since emotion and affect are fundamental components of many psychiatric conditions.
Hastings, Janna +1 more
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