Results 141 to 150 of about 1,578,929 (319)
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
HELIN E-Resources Affinity Group minutes for 11/19/2015
, 2015 Minutes of the E-Resources Affinity Group of the HELIN Consortium for November 19, 2015.
HELIN Consortium. E-Resources Affinity Group
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Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
HELIN Virtual User Affinity Group minutes for 10/21/10
, 2010 Minutes of the Virtual User Affinity Group of the HELIN Consortium for October ...
HELIN Consortium. Virtual User Affinity Group
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Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
HELIN Virtual User Affinity Group minutes for 11/09/11
, 2011 Minutes of the Virtual User Affinity Group of the HELIN Consortium for November ...
HELIN Consortium. Virtual User Affinity Group
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Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
HELIN E-Resources Affinity Group minutes for 11/08/12
, 2012 Minutes of the E-Resources Affinity Group of the HELIN Consortium for November ...
HELIN Consortium. E-Resources Affinity Group
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FEBS Open Bio, EarlyView.We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
HELIN E-Resources Affinity Group minutes for 10/28/10
, 2010 Minutes of the E-Resources Affinity Group of the HELIN Consortium for October ...
HELIN Consortium. E-Resources Affinity Group
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