Results 161 to 170 of about 2,297,328 (417)

HELIN Acquisitions Affinity Group minutes for 9/30/10

, 2010
Minutes of the Acquisitions Affinity Group of the HELIN Consortium for September ...
HELIN Consortium. Acquisitions Affinity Group
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Decision letter: Effects of common mutations in the SARS-CoV-2 Spike RBD and its ligand, the human ACE2 receptor on binding affinity and kinetics

, 2021
Ron A. M. Fouchier
openalex   +1 more source

HELIN Cataloging Affinity Group minutes for 03/27/13

, 2013
Minutes of the Cataloging Affinity Group of the HELIN Consortium for March ...
HELIN Consortium. Cataloging Affinity Group
core  

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Periadventitial Delivery of Simvastatin from Microparticles Attenuates Arteriovenous Fistula Outflow Vein Neointimal Hyperplasia

JVS - Vascular Science, 2020
Chenglei Zhao, Sean T. Zuckerman, Chuanqi Cai, Michael L. Simeon, Avishek Singh, Sreenivasulu Kilari, Julius N. Korley, Sanjay Misra   +7 more
doaj   +1 more source

TRIM21 and Fc-engineered antibodies: decoding its complex antibody binding mode with implications for viral neutralization

Frontiers in Immunology
TRIM21 is a pivotal effector in the immune system, orchestrating antibody-mediated responses and modulating immune signaling. In this comprehensive study, we focus on the interaction of TRIM21 with Fc engineered antibodies and subsequent implications for
Johannes Reusch, Linda Elise Franken, Jakob Then, Philippe Ringler, Philippe Ringler, Joachim Butzer, Thomas Juroschek, Christian Klein, Tilman Schlothauer, Laurent Larivière   +9 more
doaj   +1 more source

HELIN Cataloging Affinity Group minutes for 10/26/10

, 2010
Minutes of the Cataloging Affinity Group of the HELIN Consortium for October ...
HELIN Consortium. Cataloging Affinity Group
core  

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

HELIN Digital Collections Affinity Group minutes for 4/29/11

, 2011
Minutes of the Digital Collections Affinity Group of the HELIN Consortium for April ...
HELIN Consortium. Digital Collections Affinity Group
core