Results 161 to 170 of about 1,578,929 (319)

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

HELIN Access Services Affinity Group minutes for 10/18/12

, 2012
Minutes of the Access Services Affinity Group of the HELIN Consortium for October ...
HELIN Consortium. Access Services Affinity Group
core  

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Germinal Center Selection and Plasma Cell Differentiation. [PDF]

Immunol Rev
Sprumont A, Bannard O.
europepmc   +1 more source

HELIN E-Resources Affinity Group Minutes for 1/22/2015

, 2015
Minutes of the E-Resources Affinity Group of the HELIN Consortium for Jan ...
HELIN Consortium. E-Resources Affinity Group
core  

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

DyAb: sequence-based antibody design and property prediction in a low-data regime. [PDF]

MAbs
Lin JY, Hofmann JL, Leaver-Fay A, Liang WC, Vasilaki S, Lee E, O Pinheiro P, Tagasovska N, R Kiefer J, Wu Y, Seeger F, Bonneau R, Gligorijevic V, Watkins A, Cho K, Frey N.   +15 more
europepmc   +1 more source

HELIN E-Resources Affinity Group minutes for 10/23/2014

, 2014
Minutes of the E-Resources Affinity Group of the HELIN Consortium for Oct ...
HELIN Consortium. E-Resources Affinity Group
core  

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Evaluating molecular docking for binding affinity predictions: a systematic analysis of key parameters and the utility of AlphaFold2 structures for the Schrödinger dataset. [PDF]

J Comput Aided Mol Des
Tornesakis K, Essex JW, Cox PA, König G.   +3 more
europepmc   +1 more source