Results 171 to 180 of about 2,297,328 (417)

Cryogels with Affinity Ligands as Tools in Protein Purification

open access: yes, 2015
Affinity chromatography is one of the well-known separation techniques especially if high purity is desired. Introducing ligands on monolithic structure gives the possibility for purifying complex media such as plasma and crude extract.
Bo Mattiasson   +4 more
core   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

HELIN Virtual User Affinity Group minutes for 06/20/13

open access: yes, 2013
Minutes of the Virtual User Affinity Group of the HELIN Consortium for June ...
HELIN Consortium. Virtual User Affinity Group
core  

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

PRODIGY: a web server for predicting the binding affinity of protein-protein complexes

open access: yesBioinform., 2016
L. Xue   +4 more
semanticscholar   +1 more source

HELIN Reference Services Affinity Group minutes for 6/13/11

open access: yes, 2011
Minutes of the Reference Services Affinity Group of the HELIN Consortium for June ...
HELIN Consortium. Reference Services Affinity Group
core  

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Improved methods for predicting peptide binding affinity to MHC class II molecules

open access: yesImmunology, 2018
Kamilla K Jensen   +8 more
semanticscholar   +1 more source

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