Results 31 to 40 of about 2,414,823 (352)

Polymer Microparticles Prolong Delivery of the 15-PGDH Inhibitor SW033291

Pharmaceutics, 2021
As the prevalence of age-related fibrotic diseases continues to increase, novel antifibrotic therapies are emerging to address clinical needs. However, many novel therapeutics for managing chronic fibrosis are small-molecule drugs that require frequent ...
Alan B. Dogan, Nathan A. Rohner, Julianne N. P. Smith, Jessica A. Kilgore, Noelle S. Williams, Sanford D. Markowitz, Horst A. von Recum, Amar B. Desai   +7 more
doaj   +1 more source

Characterizing synaptic protein development in human visual cortex enables alignment of synaptic age with rat visual cortex

Frontiers in Neural Circuits, 2015
Although many potential neuroplasticity based therapies have been developed in the lab, few have translated into established clinical treatments for human neurologic or neuropsychiatric diseases.
Joshua G.A Pinto, David G Jones, Kate eWilliams, Kathryn M Murphy, Kathryn M Murphy   +4 more
doaj   +1 more source

Systems analysis shows that thermodynamic physiological and pharmacological fundamentals drive COVID‐19 and response to treatment

Pharmacology Research & Perspectives, 2022
Why a systems analysis view of this pandemic? The current pandemic has inflicted almost unimaginable grief, sorrow, loss, and terror at a global scale. One of the great ironies with the COVID‐19 pandemic, particularly early on, is counter intuitive.
Richard J. Head, Eugenie R. Lumbers, Bevyn Jarrott, Felix Tretter, Gary Smith, Kirsty G. Pringle, Saiful Islam, Jennifer H. Martin   +7 more
doaj   +1 more source

Novel Synthesis of IMC-48 and Affinity Evaluation with Different i-Motif DNA Sequences

Molecules, 2023
During the last decade, the evidence for the biological relevance of i-motif DNA (i-DNA) has been accumulated. However, relatively few molecules were reported to interact with i-DNA, and a controversy concerning their binding mode, affinity, and ...
Florian Berthiol, Joseph Boissieras, Hugues Bonnet, Marie Pierrot, Christian Philouze, Jean-François Poisson, Anton Granzhan, Jérôme Dejeu, Eric Defrancq   +8 more
doaj   +1 more source

The Impact of Affinity on World Economic Integration: The Case of Japanese Foreign Direct Investment [PDF]

, 2012
This paper finds that a country’s affinity with a foreign country has a positive effect on foreign direct investment flows from it to that country, by analyzing Japanese foreign direct investment outflows during the period of 1995 to 2009.
CHEY Hyoung-kyu
core   +2 more sources

An opinion dynamics model based on affinity and social noise

Frontiers in Physics, 2022
Most previous works have studied the evolution of opinions based on the Hegselmann–Krause model, the Deffuant–Weisbuch model, and the Sznajd model. However, the influence of social influence on opinions is discussed less.
Jusheng Liu, Jianjia He, Jianjia He, Jianjia He, Zhiping Qiu, Shengxue He   +5 more
doaj   +1 more source

Doctors in Private Practice: A Systematic Review of the Perceived Working Conditions, Psychological Health, and Patient Care

Merits
Medical doctors are at risk of poor mental health, linked to their working conditions. However, little distinction is made between private and public practice where working conditions differ.
Hannah Karrlein, Kevin Rui-Han Teoh, Marleen Reinke, Gail Kinman, Nicola Cordell, Joanna Yarker   +5 more
doaj   +1 more source

Carbon nanotube decorated magnetic microspheres as an affinity matrix for biomolecules [PDF]

, 2013
Carbon nanotube (CNT) decorated magnetic microspheres were fabricated to develop a multimodal platform that utilizes non-covalent molecular interactions of CNTs to magnetically separate biomolecules.
Kolkar Mohammed, Javed Hussain Niazi, Ünal, Hayriye   +1 more
core   +1 more source

A new highly digestible prescription diet containing Bacillus velezensis DSM 15544, fructo-oligosaccharides, plasma immunoglobulin, yeast and sepiolite for the management of acute diarrhea in dogs—a randomized double-blinded, controlled trial

Frontiers in Veterinary Science
ObjectiveTo determine if a newly formulated diet with safe and highly digestible ingredients, Bacillus velezensis DSM 15544, fructo-oligosaccharides, animal plasma protein, dried whole yeast and sepiolite contributes toward the management of canine acute
I. Jeusette, E. Apper, V. Fragua, N. Sanchez, C. Torre, L. Badiella, J. Puig, J. Puig, E. Ballester, A. Jurado, L. Feo Bernabe, L. Feo Bernabe   +11 more
doaj   +1 more source

Affinity Proteomics Exploration of Melanoma Identifies Proteins in Serum with Associations to T-Stage and Recurrence

Translational Oncology, 2017
BACKGROUND: Blood-based proteomic profiling may aid and expand our understanding of diseases and their different phenotypes. The aim of the presented study was to profile serum samples from patients with malignant melanoma using affinity proteomic assays
Sanna Byström, Claudia Fredolini, Per-Henrik Edqvist, Etienne-Nicholas Nyaiesh, Kimi Drobin, Mathias Uhlén, Michael Bergqvist, Fredrik Pontén, Jochen M. Schwenk   +8 more
doaj   +1 more source