TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk
Hepatology, EarlyView., 2022 The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam +10 more
wiley +1 more source
In vitro Evaluation of Sorghum Genotypes for their Resistance to Aflatoxin B1 Contamination [PDF]
, 2023 Sorghum is Ethiopia's main staple meal and the most significant nutritional security crop. Aflatoxin contamination in sorghum grains has been documented all across the world, including Ethiopia.
Taye, Wondimeneh
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Voltammetric Determination of Aflatoxin B1 [PDF]
, 2014 For the first time the possibility of voltammetry used for the determination of aflatoxin B1 on a glassy carbon electrode was shown. The effect of pH of a supporting electrolyte on the analytical signal of aflatoxin B1 has been investigated and it was ...
Deryabina, Valentina Ivanovna +3 more
core +1 more source
Comparison of two Analytical Methods (ELISA and LC-MS/MS) for Determination of Aflatoxin B1 in Corn and Aflatoxin M1 in Milk [PDF]
, 1934 The aim of this paper is to assess the closeness of agreement between results of ELISA and LC-MS/MS methods for determination of aflatoxin B1 in corn and aflatoxin M1 in milk.
Stefanovic, Srdjan +6 more
core +1 more source
Aflatoxins contamination in chilli samples from Pakistan [PDF]
, 2007 The aim of this study was to prioritise disease and pest constraints in chilli by highlighting aflatoxin concentrations to assist local farmers in control. All samples contained aflatoxin B1 and high levels were obtained from all ground samples.
Paterson, R. R. M.
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Antifungal Activity against Aspergillus parasiticus of Supernatants from Whey Permeates Fermented with Kefir Grains [PDF]
, 2015 Aspergillus parasiticus, a common fungal contaminant in food, produces aflatoxin B1, which is classified as human carcinogen. Kefir is an ancient fermented beverage obtained by the fermentation of different substrates with kefir grains.
Alconada Magliano, Teresa María +6 more
core +3 more sources
Point mutations of the P53 gene, human hepatocellular carcinoma and aflatoxins [PDF]
, 1993 The tumor suppressor p53 exerts important protective functions towards DNA-damaging agents. Its inactivation by allelic deletions or point mutations within the P53 gene as well as complex formation of wildtype p53 with cellular or viral proteins is a ...
Alexander L. Gerbes +40 more
core +1 more source
Antifungal Activity against Aspergillus parasiticus of Supernatants from Whey Permeates Fermented with Kefir Grains [PDF]
, 2015 Aspergillus parasiticus, a common fungal contaminant in food, produces aflatoxin B1, which is classified as human carcinogen. Kefir is an ancient fermented beverage obtained by the fermentation of different substrates with kefir grains.
Alconada, Teresa +6 more
core +1 more source
Complex regulation of the aflatoxin biosynthesis gene cluster of Aspergillus flavus in relation to various combinations of water activity and temperature [PDF]
, 2009 A microarray analysis was performed to study the effect of varying combinations of water activity and temperature on the activation of aflatoxin biosynthesis genes in Aspergillus flavus grown on YES medium. Generally A.
Abdel-Hadi, Ahmed +3 more
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Toxicity of aflatoxin B1 towards the vitamin D receptor (VDR) [PDF]
, 2015 This research describes an unexpected toxicity of the aflatoxin B1 towards the vitamin D receptors. Rickets is a childhood disease, and calcium deficiency is the aetiological cause in Africa, being primarily associated with nutritional problems; in ...
COSTANZO, PAOLA +4 more
core +1 more source