TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk
Hepatology, EarlyView., 2022 The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam +10 more
wiley +1 more source
Effect of Hydroethanolic Saffron petals’ extract on performance, carcass characteristics and blood parameters of Japanese quails challenged by aflatoxin [PDF]
Zirā̒at va Fanāvarī-i Za̒farān, 2018 The purpose of this study is to investigate the effect of Hydroethanolic saffron petals’ extract (HSPE) on the performance, carcass characteristics and blood biochemical parameters of Japanese quails challenged with Aflatoxin B1.
Seyyed Javad Hosseini-Vashan +2 more
doaj +1 more source
Comparison of two Analytical Methods (ELISA and LC-MS/MS) for Determination of Aflatoxin B1 in Corn and Aflatoxin M1 in Milk [PDF]
, 1934 The aim of this paper is to assess the closeness of agreement between results of ELISA and LC-MS/MS methods for determination of aflatoxin B1 in corn and aflatoxin M1 in milk.
Stefanovic, Srdjan +6 more
core +1 more source
Toxins, 2014 Aflatoxin B1, a type of highly toxic mycotoxin produced by some species belonging to the Aspergillus genus, such as Aspergillus flavus and Aspergillus parasiticus, is widely distributed in feed matrices.
Wei Zhang +6 more
doaj +1 more source
Complex regulation of the aflatoxin biosynthesis gene cluster of Aspergillus flavus in relation to various combinations of water activity and temperature [PDF]
, 2009 A microarray analysis was performed to study the effect of varying combinations of water activity and temperature on the activation of aflatoxin biosynthesis genes in Aspergillus flavus grown on YES medium. Generally A.
Abdel-Hadi, Ahmed +3 more
core +1 more source
Report from the 5th international symposium on mycotoxins and toxigenic moulds : challenges and perspectives (MYTOX) held in Ghent, Belgium, May 2016 [PDF]
, 2016 The association research platform MYTOX “Mycotoxins and Toxigenic Moulds” held the 5th meeting of its International Symposium in Ghent, Belgium on 11 May 2016.[...
Audenaert, Kris +2 more
core +9 more sources
Assessment of aflatoxin B1 in livestock feed and feed ingredients by high-performance thin layer chromatography [PDF]
Veterinary World, 2015 Aim: Detection of aflatoxin B1 in Livestock compound Feed and feed ingredients by high-performance thin layer chromatography (HPTLC). Materials and Methods: Chromatography was performed on HPTLC silica gel 60 F 254, aluminum sheets by CAMAG automatic ...
Korrapati Kotinagu +2 more
doaj +1 more source
Point mutations of the P53 gene, human hepatocellular carcinoma and aflatoxins [PDF]
, 1993 The tumor suppressor p53 exerts important protective functions towards DNA-damaging agents. Its inactivation by allelic deletions or point mutations within the P53 gene as well as complex formation of wildtype p53 with cellular or viral proteins is a ...
Alexander L. Gerbes +40 more
core +1 more source
Antifungal Activity against Aspergillus parasiticus of Supernatants from Whey Permeates Fermented with Kefir Grains [PDF]
, 2015 Aspergillus parasiticus, a common fungal contaminant in food, produces aflatoxin B1, which is classified as human carcinogen. Kefir is an ancient fermented beverage obtained by the fermentation of different substrates with kefir grains.
Alconada, Teresa +6 more
core +1 more source
Production of antibody against aflatoxin B1 [PDF]
Applied and Environmental Microbiology, 1977 Antibody against aflatoxin B1 was obtained after one multiple-site injection of bovine serum albumin-aflatoxin B1 conjugate into rabbits. The antibody has greatest binding efficiency for aflatoxin B1, less efficiency for B2, G1, and Q1, and least for aflatoxicol, G2, and M1.
F S, Chu, I, Ueno
openaire +2 more sources