The effect of early life aflatoxin exposure on growth, immune function and cancer predisposition [PDF]
, 2013 Aflatoxin exposure through contamination of dietary staples is prevalent in developing regions such as sub-Saharan Africa. Aflatoxin exposure has been linked to a G→T transversion in p53, which has been suggested to be the main mechanism of aflatoxin ...
Castelino, Jovita Marie
core +6 more sources
Impact of ecophysiological factors on biocontrol of aflatoxin contamination of maize by atoxigenic aspergillus flavus strains [PDF]
, 2013 This study has (a) evaluated the biodiversity in toxigenic mycobiota associated with maize from subsistence farmers’ stores in five climatic regions of Lesotho in two seasons, (b) compared the effect of ecophysiological factors on interactions between ...
Mohale, Sejakhosi Alexis
core +7 more sources
Molecular ecology of aspergillus section flavi species : approaches to understand the role of aflatoxin genes in aflatoxin biosynthesis [PDF]
, 2011 This is the first study to integrate and correlate the effect of ecophysiological factors on the life cycle of Aspergillus flavus by carrying out complementary work on gene expression of the aflatoxin gene cluster, with growth, sporulation and ...
Abdel-Hadi, Ahmed
core +7 more sources
TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk
Hepatology, EarlyView., 2022 The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam +10 more
wiley +1 more source
Impact of environmental and plant factors on Aspergillus section Flavi isolated from maize in Italy [PDF]
, 2007 The exceptional hot weather conditions in Italy during the summer of 2003 resulted in an optimal environment for the development of Aspergillus section Flavi in maize and, consequently, for aflatoxin production.
Giorni, Paola
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The production of aflatoxin B1 or G1 by Aspergillus parasiticus at various combinations of temperature and water activity is related to the ratio of aflS to aflR expression [PDF]
, 2010 The influence of varying combinations of wateractivity (aw) and temperature on growth, aflatoxin biosynthesisand aflR/aflS expression of Aspergillus parasiticuswas analysed in the ranges 17-42°C and 0.90-0.99 aw.Optimum growth was at 35°C.
Rüfer, C. E. +12 more
core +1 more source
Fv antibodies to aflatoxin B1 derived from a pre-immunized antibody phage display library system [PDF]
, 2002 The production and characterization of recombinant antibodies to aflatoxin B[SUB1] (AFB[SUB1]), a potent mycotoxin and carcinogen is described. The antibody fragments produced were then applied for use in a surface plasmon resonance-based biosensor ...
Daly, Stephen J. +6 more
core +2 more sources
Assessment of aflatoxin B1 in livestock feed and feed ingredients by high-performance thin layer chromatography [PDF]
Veterinary World, 2015 Aim: Detection of aflatoxin B1 in Livestock compound Feed and feed ingredients by high-performance thin layer chromatography (HPTLC). Materials and Methods: Chromatography was performed on HPTLC silica gel 60 F 254, aluminum sheets by CAMAG automatic ...
Korrapati Kotinagu +2 more
doaj +1 more source
Food and Agricultural Immunology, 2022 This study evaluated the presence of aflatoxin B1 in five different animal feeds collected from manufacturers, suppliers and consumers and its possible reduction by heating at 100°C for 180 min.
Anjelina W. Mwakosya +5 more
doaj +1 more source
Effect of Hydroethanolic Saffron petals’ extract on performance, carcass characteristics and blood parameters of Japanese quails challenged by aflatoxin [PDF]
Zirā̒at va Fanāvarī-i Za̒farān, 2018 The purpose of this study is to investigate the effect of Hydroethanolic saffron petals’ extract (HSPE) on the performance, carcass characteristics and blood biochemical parameters of Japanese quails challenged with Aflatoxin B1.
Seyyed Javad Hosseini-Vashan +2 more
doaj +1 more source