Results 171 to 180 of about 168,150 (214)

Antineoplastic Activity of Aflatoxin B1

Nature, 1968
THE aflatoxins, a group of related mycotoxins produced by Aspergillus flavus, have been extensively evaluated for biological activity. They are carcinogenic in animals1–5. The aflatoxin B1 fraction has been teratogenic in hamsters6, probably mutagenic in micro-organisms7 and caused chromosome breakage in mammalian cell cultures7,8.
openaire   +2 more sources

The neurotoxicity of aflatoxin B1 in the rat

Toxicology, 1983
The effects of repeated intraperitoneal administration of aflatoxin B1 on the peripheral and central nervous systems of rats were investigated. Biochemical markers of neurotoxicity were monitored in nervous tissues following aflatoxin B1 dosage and after the cessation of aflatoxin B1 administration.
openaire   +2 more sources

Residues of aflatoxin B1 in broiler meat: Effect of age and dietary aflatoxin B1 levels

Food and Chemical Toxicology, 2010
This study describes the effect of dietary levels of aflatoxin B1 (AFB1) and age of the birds upon the residue level in liver and muscles of broiler chicks. In three different experiments broiler chicks of 7, 14 and 28 days of age were kept for 7 days on contaminated rations having 1600, 3200 and 6400 μg/kg AFB1.
Zahid, Hussain, Muhammad Zargham, Khan, Ahrar, Khan, Ijaz, Javed, Muhammad Kashif, Saleemi, Sultan, Mahmood, Muhammad Rafique, Asi   +6 more
openaire   +2 more sources

Effects of aflatoxin B1 on myelopoiesis in vitro

Toxicology, 1991
The short-term cultures of mouse myeloid progenitor cells for granulocytes and monocytes, granulocyte-monocyte colony-forming units (CFU-GM) (CFU-GM assay) and mouse long-term bone marrow culture (LTBMC) were used to investigate the hemopoietic suppression caused by aflatoxin B1 (AFB1).
V, Cukrová, E, Langrová, M, Akao
openaire   +2 more sources

Thermal stability of aflatoxin B1 and ochratoxin A

Mycotoxin Research, 2008
Within this research project, the LCI (Lebensmittelchemisches Institut des Bundesverbandes der Deutschen Süßwarenindustrie e. V.) conducted systematic studies to determine the thermal stability of the mycotoxins ochratoxin A (OTA) and aflatoxin B1, as the available literature provides contradictory data.
M, Raters, R, Matissek
openaire   +2 more sources

Photophysics and photochemistry of aflatoxins B1 and B2

Photochemical & Photobiological Sciences, 2011
Aflatoxins are mycotoxins produced by fungi of the genus Aspergillus, which is widely spread in the tropics and subtropics. To date, aflatoxin phototoxicity has been recognized, but the mechanism responsible for this phototoxicity has not been fully characterized.
J C, Netto-Ferreira, B, Heyne, J C, Scaiano   +2 more
openaire   +2 more sources

Fluorescence changes of aflatoxins B1 and G1

Zeitschrift für Lebensmittel-Untersuchung und -Forschung, 1975
The effects of various factors, such as pH, buffer, sodiumchloride and ultra-violet radiation on the fluorescence of aflatoxins B1 and G1 have been studied. The fluorescence characteristics of aflatoxins B1 and G1 underwent a marked change at pH values above 7.2.
H R, Prasanna, S R, Gupta, L, Viswanathan, T A, Venkitasubramanian   +3 more
openaire   +2 more sources

Characterization of monosomes produced by aflatoxin B1

Chemico-Biological Interactions, 1975
A single injection of 1.5 mg aflatoxin B1 per kg body weight produced approx. 70% disaggregation of rat liver polysomes into monosomes within 18 h. Isolated monosomes dissociated into 40 S subunits during centrifugation in linear sucrose gradients containing 0.3 M KCI. The 4 S to 5 S molar RNA ratio of the monosomes was calculated to be 0.6, indicating
L C, Hayes, F V, Plapp, L L, Tilzer, M, Chiga   +3 more
openaire   +2 more sources

Uptake of aflatoxin B1 by the skin of rats

Experientia, 1970
Nachweis der Absorption von Aflatoxin B1 durch die Rattenhaut. Die toxische Leberwirkung nach der Hautbepinselung entsprach den von anderen Autoren gefundenen Verhaltnissen bei peroraler oder intraperitonealer Verabreichung.
R D, Wei, G X, Liu, S S, Lee
openaire   +2 more sources

Metabolism of aflatoxin B1 by the guinea-pig

Food and Cosmetics Toxicology, 1973
Abstract Aflatoxin B 1 was given by ip injection to year-old female guinea-pigs and 6 hr later aflatoxin B 1 and its metabolites were recovered and isolated chromatographically. Approximately 14% of the administered toxin was represented by the isolated compounds.
M T, Koes, L J, Forrester, H D, Brown
openaire   +2 more sources