Results 61 to 70 of about 15,299 (194)

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

VIEW, EarlyView.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source

Carryover of Aflatoxin From Dairy Feed to Milk: A Systematic Review (1 January 2004–31 December 2024)

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Aflatoxins, toxic metabolites produced by Aspergillus species, are frequently reported contaminants of dairy cattle feed worldwide, particularly in tropical and subtropical regions where climatic conditions favor fungal growth, and they can be transferred into milk and dairy products.
Queenta Ngum Nji, Richard Temitope Fagbohun, Oluwafemi Ayodeji Adebo, Patrick Berka Njobeh   +3 more
wiley   +1 more source

Binding of Aflatoxin B1 to Bifidobacteria In Vitro

Journal of Food Protection, 2000
Aflatoxins are mycotoxins that cause health and economic problems when they contaminate food and feed. One potential method for reducing human health effects due to aflatoxin ingestion is to block uptake via binding by bacteria that either make up the normal gut flora or are present in fermented foods in our diet.
J T, Oatley, M D, Rarick, G E, Ji, J E, Linz   +3 more
openaire   +2 more sources

Immunomodulatory and Cytotoxic Properties of Enniatin B1 in Porcine Alveolar Macrophages

Journal of Applied Toxicology, Volume 46, Issue 9, Page 3220-3231, September 2026.
ABSTRACT This study investigates the immunomodulatory effects of Enniatin B1 (ENNB1), an emerging mycotoxin, on porcine alveolar macrophages (PAMs), a species‐specific model relevant to human innate immunity. PAMs were exposed to increasing ENNB1 concentrations (0.5–6 μM) over 6, 24, and 48 h.
Sara Frazzini, Francesca Caloni, Paola Fossati, Giancarlo Ruffo, Luciana Rossi   +4 more
wiley   +1 more source

Investigation of Aspergillus flavus Infection and Aflatoxin Accumulation in Pulses During Growth and Development

Legume Science, Volume 8, Issue 3, September 2026.
ABSTRACT Aflatoxins (AFL) are mycotoxins produced by Aspergillus flavus that pose major risks to food safety. This study evaluated fungal growth and AFL production in planta across the following five pulse species: chickpeas (Cicer arietinum L.), lentils (Lens culinaris Medik.), peas (Pisum sativum L.), soybeans (Glycine max L.), and with corn (Zea ...
Emily Branstad‐Spates, Kanniah Rajasekaran, Elizabeth Wyman, Christine Sickler, Carol Carter‐Wientjes, Matthew Lebar   +5 more
wiley   +1 more source

Gut Microbiota, Immunity, and Metabolism in the Progression From Chronic Liver Disease to Hepatocellular Carcinoma

Advanced Science, Volume 13, Issue 44, 7 August 2026.
This review explains how chronic liver injury progresses toward hepatocellular carcinoma through interconnected changes in gut microbes, metabolism, immunity, fibrosis, and diet. It highlights microbial metabolites, bile‐acid signaling, immune dysfunction, and nutritional or microbiome‐based interventions as opportunities to identify risk earlier ...
Yi Hu, Caiyan Lin, Lijie Zhang, Xue Jiang, Huawen Li, Yangzhe Wu   +5 more
wiley   +1 more source

PharmVar GeneFocus: CYP1A2—Clinical Impact, Genetic Variation, and Updated Nomenclature

Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 313-323, August 2026.
The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly polymorphic human CYP1A2 gene. CYP1A2 plays a crucial role in the biotransformation of several commonly used drugs, including antipsychotics, antidepressants, anxiolytics, and methylxanthines.
Katalin Monostory, Gonzalo Villapalos Garcia, Dora Koller, Solomon Adams, Chad A. Bousman, Evangelia Eirini Tsermpini, Michelle Whirl‐Carrillo, Amy J. Turner, Volker M. Lauschke, Mohamed Nagy, Erin C. Boone, Teri E. Klein, Pablo Zubiaur, Andrea Gaedigk   +13 more
wiley   +1 more source

Applications of Bioinorganic Nano‐Based Delivery Systems—Diagnostics and Therapeutics

Drug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT Nanotechnology has emerged as a promising avenue for producing nanomedicines as alternatives to conventional drugs. Many organic nanoparticles, such as liposomes used in formulations like Doxil, Onivyde, and Marqibo, are approved by the Food and Drug Administration (FDA) and instrumental in treating various types of cancers.
Frank Ssengooba, Jubilee Andrew, Donald Fernandes   +2 more
wiley   +1 more source

Micro‐ and Nanostructured Materials in Edible Coatings for the Preservation of Fruits and Vegetables

eFood, Volume 7, Issue 4, August 2026.
Graphical representation of micro‐ and nanostructured materials in edible coatings for the preservation of fruits and vegetables. ABSTRACT Edible coatings based on advanced nanostructured materials have emerged as effective strategies for extending the shelf life and maintaining the quality of fresh fruits and vegetables.
Carlos Méndez‐Durazno, Katherine Vaca‐Escobar, Fernanda Landeta‐Constante, Santiago Guerrero‐Jaramillo, Milton Villacís‐García, Patricio J. Espinoza‐Montero   +5 more
wiley   +1 more source

Pharmacokinetics of intratracheally administered aflatoxin B1

Toxicology and Applied Pharmacology, 1991
High concentrations of the carcinogen aflatoxin B1 (AFB1) are commonly found in respirable, airborne grain dusts, and inhaled AFB1 has been shown to be a risk factor for occupational pulmonary carcinogenesis. The fate of AFB1 exposure via the respiratory tract is therefore of interest in an evaluation of potential occupational risk. The pharmacokinetic
Coulombe, Roger A., Jr., Huie, J. M., Ball, R. W., Sharma, R. P., Wilson, D. W.   +4 more
openaire   +3 more sources