TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk
The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam +10 more
wiley +1 more source
Dietary aflatoxin exposure and impaired growth in young children from Benin and Togo: cross sectional study [PDF]
Fetal and early childhood environment, including the nutritional status of the pregnant mother and the infant, are considered critical for growth and risk of disease in later life.
Cardwell, K +6 more
core +3 more sources
Background. Mycotoxins are biologically active secondary metabolites produced by fungal species in the genera Aspergillus, Penicillium, and Fusarium and grow in a variety of foods including cereals, grains, nuts, oil seeds, fruits, vegetables, cocoa ...
Joseph Gaizi, Saphan Muzoora
doaj +1 more source
Aflatoxins in Food and Feed: An Overview on Prevalence, Detection and Control Strategies
Aflatoxins produced by the Aspergillus species are highly toxic, carcinogenic, and cause severe contamination to food sources, leading to serious health consequences.
Dipendra K. Mahato +6 more
doaj +1 more source
Quantitative Analysis of Total Aflatoxins in Dairy Cattle Feed Using a Competitive Lateral Flow Immunoassay: A Regional Study in Tigray, Ethiopia. [PDF]
Quantitative analysis of total aflatoxins in dairy cattle feed across five urban centres in Tigray, Ethiopia, revealed that 22.4% of samples exceeded national limits and 29.1% surpassed EU thresholds. Higher contamination levels were associated with roughage‐based feed, poor storage conditions and the presence of toxigenic Aspergillus flavus and A ...
Zeweld SW, Welearegay MA, Tarekegn EK.
europepmc +2 more sources
Differentiation between Aspergillus flavus and Aspergillus parasiticus from Pure Culture and Aflatoxin-Contaminated Grapes Using PCR-RFLP Analysis of aflR-aflJ Intergenic Spacer [PDF]
Aflatoxins (AFs) represent the most important single mycotoxin-related food safety problem in developed and developing countries as they have adverse effects on human and animal health. They are produced mainly by Aspergillus flavus and A.
Atoui, Ali +5 more
core +2 more sources
Mycotoxin exposure assessments in a multi-center European validation study by 24-hour dietary recall and biological fluid sampling [PDF]
The European Food Consumption Validation (EFCOVAL) project includes 600 men and women from Belgium, the Czech Republic, France, the Netherlands, and Norway, who had given serum and 24-hour urine samples, and completed 24-hour dietary recall (24-HDR ...
Abbeddou, Souheila +11 more
core +1 more source
A suitable method for routine analysis of aflatoxins M1, M2, B1, B2, G1, G2 in peanut by ultra-high performance liquid chromatography-tandem mass spectrometry was developed and validated.
André Victor Sartori +5 more
doaj +7 more sources
Foreword: mycotoxins in a changing world [PDF]
This special issue arose because of the changes in the global landscape in relation to the impact and implications of our changing climate on food security and quality, consumer habits, trade and economics, regulations and scientific thinking.
Battilani, Paola +2 more
core +1 more source
The Occurrence of Aflatoxins in Date Palm (Phoenix dactylifera L.) Worldwide
Due to global warming, the risk of aflatoxins exposure through the consumption of contaminated food has increased. Aflatoxins pose serious health hazards to humans’ and animals’ health because of their carcinogenic, mutagenic, and teratogenic properties ...
Merfat Abdulrahman Almaghrabi
doaj +1 more source

