Results 71 to 80 of about 32,988 (232)

N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential

iNew Medicine, EarlyView.
ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen, Ru Ya, Ziling Zhang, Siyue Dong, Seol Hee Park, Wonhyo Seo, Yong He   +6 more
wiley   +1 more source

Immunomodulatory and Cytotoxic Properties of Enniatin B1 in Porcine Alveolar Macrophages

Journal of Applied Toxicology, EarlyView.
ABSTRACT This study investigates the immunomodulatory effects of Enniatin B1 (ENNB1), an emerging mycotoxin, on porcine alveolar macrophages (PAMs), a species‐specific model relevant to human innate immunity. PAMs were exposed to increasing ENNB1 concentrations (0.5–6 μM) over 6, 24, and 48 h.
Sara Frazzini, Francesca Caloni, Paola Fossati, Giancarlo Ruffo, Luciana Rossi   +4 more
wiley   +1 more source

Occurrence of total aflatoxins (B1, B2, G1, G2) in commercial peanut and peanut butter from the Saudi market in the period from 2015 to 2020

Toxicology Reports
Nut products are susceptible to contamination with mycotoxin, especially aflatoxins, which results of mold growth during harvest or storage. This study aimed to evaluate the occurrence of aflatoxins in peanut products from the Saudi market.
Abdullah Al tamim, Rawan Alharbi, Zeyad Aldosari, Yaser Almasoud, Abdullah A. Al Sayari, Mohammed A. Almutairi, Abdullah M. Alowaifeer, Hibah Alharbi   +7 more
doaj   +1 more source

Beyond Tradition: An Integrated Toxicological, Ecological, and Public Health Perspective on Aristolochic Acids

Journal of Applied Toxicology, EarlyView.
ABSTRACT Aristolochia species have long been used in traditional medicine for their presumed anti‐inflammatory, analgesic and antimicrobial properties. However, extensive toxicological and epidemiological evidence now demonstrates that these plants contain aristolochic acids (AAs) I and II, highly potent nephrotoxic, genotoxic, and carcinogenic ...
Victor Ventura de Souza, Lara Rodrigues De Andrade, Tatiana da Silva Souza   +2 more
wiley   +1 more source

The Occurrence of Aflatoxins in Nuts and Dry Nuts Packed in Four Different Plastic Packaging from the Romanian Market

Microorganisms, 2020
Mycotoxins are secondary metabolites produced by various fungi. A very important category of mycotoxins are aflatoxins, considered to be the most dangerous in humans.
Adrian Maximilian Macri, Ioana Pop, Daniel Simeanu, Diana Toma, Ion Sandu, Liliana Lacramioara Pavel, Olimpia Smaranda Mintas   +6 more
doaj   +1 more source

Assessment of dried blood spots for multi-mycotoxin biomarker analysis in pigs and broiler chickens [PDF]

, 2019
Dried blood spots (DBSs), a micro-sampling technique whereby a drop of blood is collected on filter paper has multiple advantages over conventional blood sampling regarding the sampling itself, as well as transportation and storage.
Croubels, Siska, De Baere, Siegrid, Devreese, Mathias, Gougoulias, Christos, Lauwers, Marianne, Letor, Ben, Romera Sierra, Eva Maria, Sevastiyanova, Milena   +7 more
core   +1 more source

Nutrient composition and heavy metal accumulation in water hyacinth [Eichhornia crassipes (Mart.) Solms] and water lettuce (Pistia stratiotes L.) from the Dande River, Nepal: Implications for use as alternative feed resources

JSFA reports, EarlyView.
Abstract Background The proliferation of invasive aquatic macrophytes poses a significant ecological challenge globally, while many tropical regions face chronic shortages of affordable livestock feed. This study addresses this dual problem by assessing two invasive species, water hyacinth (Eichhornia crassipes) and water lettuce (Pistia stratiotes ...
Anish Balchhaudi, Aanchal Shrestha, Akash Adhikari, Sujan Adhikari, Abhishek Adhikari, Rabin Acharya   +5 more
wiley   +1 more source

Determination of Aflatoxins B1 and B2 in Powdered Milk Using Modified Liquid Chromatography Method [PDF]

Journal of Kerman University of Medical Sciences, 2014
Background & Aims: In this study, using a liquid-liquid microextraction method for pre-concentration trace amounts of aflatoxins, the amount of Aflatoxins B1 and B2 in powdered milk was determined.
A Amini, D Afzali-Grooh, M Chamsaz
doaj  

Recent Advances in Aflatoxins Detection Based on Nanomaterials

Nanomaterials, 2020
Aflatoxins are the secondary metabolites of Aspergillus flavus and Aspergillus parasiticus and are highly toxic and carcinogenic, teratogenic and mutagenic. Ingestion of crops and food contaminated by aflatoxins causes extremely serious harm to human and
Chunlei Yan, Qi Wang, Qingli Yang, Wei Wu   +3 more
doaj   +1 more source

Resíduos de aflatoxina B1 em fígado de codornas japonesas (Coturnix japonica) expostas a alimentos contaminados e à corticosterona exógena [PDF]

, 2013
The combined effect of aflatoxin B1 (AFB1 ) exposition and stress induced by corticosterone (CORT) upon the residual aflatoxin levels in livers of Japanese quail was examined.
Chiacchiera, Stella Maris, Dalcero, Ana Maria, Magnoli, Alejandra Paola, Marin, Raul Hector, Rosa, Carlos Alberto da Rocha   +4 more
core   +1 more source