Results 191 to 200 of about 155,399 (295)

Nanoengineered photosensitizers for photodynamic priming to overcome P‐glycoprotein‐mediated multidrug resistance

Photochemistry and Photobiology, EarlyView.
Verteporfin's subcellular localization governs its ability to deplete ATP. LysoPC‐conjugated VP accumulates in lysosomes and spares mitochondria, while liposomal and NanoVP formulations target mitochondria, where light activation triggers membrane depolarization and ATP depletion, overcoming resistance seen with free‐form VP. Abstract P‐glycoprotein (P‐
Idrisa Rahman, Anju Meda, Kaitlyn A. Moore, Payal Srivastava, Anika Dasgupta, Andaleeb Sajid, Suresh V. Ambudkar, Huang‐Chiao Huang   +7 more
wiley   +1 more source

Atypical presentation of macular serpiginous choroiditis masquerading as age related macular degeneration. [PDF]

Am J Ophthalmol Case Rep
Faghihi S, Eshkoly-Lior T, Feo A, Sarraf D.   +3 more
europepmc   +1 more source

Techniques for subretinal injections in animals

Veterinary Ophthalmology, Volume 28, Issue 2, Page 506-518, March 2025.
Abstract Subretinal injections are not commonly performed during clinical treatment of animals but are frequently used in laboratory animal models to assess therapeutic efficacy and safety of gene and cell therapy products. Veterinary ophthalmologists are often employed to perform the injections in the laboratory animal setting, due to knowledge of ...
Ryan F. Boyd, Simon M. Petersen‐Jones
wiley   +1 more source

Gene Therapy for Wet Age-Related Macular Degeneration. [PDF]

Bioengineering (Basel)
Barthelemy N, Sridhar J, Sengillo JD.
europepmc   +1 more source

An eye on long‐duration spaceflight: Controversies, countermeasures and challenges

Experimental Physiology, EarlyView.
Abstract Space flight‐associated neuroocular syndrome (SANS) is a consequence of long‐duration space flight and is detected in two‐thirds of astronauts. In‐flight, this can cause a change in the refraction of the eyes, requiring graded hypermetropic ‘superfocus adjustable’ glasses, optic nerve head oedema and choroidal folds.
Vincent Wing Sum Ng, Susan Patricia Mollan   +1 more
wiley   +1 more source

Drug Delivery Technologies for the Treatment of Age-Related Macular Degeneration. [PDF]

Adv Sci (Weinh)
Rodriguez-Cruz JJ, Cutrufello J, Lam M, Nallaparaju S, Peppas NA.   +4 more
europepmc   +1 more source

Reduced Vessel Density of the Choriocapillaris during Anti-Vascular Endothelial Growth Factor Therapy for Neovascular Age-Related Macular Degeneration

, 2019
Taiichi Hikichi, Mitsuko Agarie
openalex   +1 more source

Frequency responses of human magnetophosphene perception thresholds during dark adaptation point to rod modulation

Experimental Physiology, EarlyView.
Abstract Magnetophosphenes are flickering lights perceived when an extremely low frequency magnetic field generates a sufficiently strong electric field in the head. Understanding how phosphenes are produced is crucial, as they form the basis for international safety standards and guidelines for both workers and the general population.
Nicolas Bouisset, Andres Carvallo, Sebastien Villard, Ilkka Laakso, Alexandre Legros   +4 more
wiley   +1 more source

Targeted Fluorescence Imaging of Bevacizumab-800CW in Patients with Neovascular Age-Related Macular Degeneration. [PDF]

J Nucl Med
Schmidt I, Volkmer P, Müskens RPHM, van der Waaij AM, van Dam GM, Huiskamp EA, Nagengast WB.   +6 more
europepmc   +1 more source

Relevance of Complement Factor H–Related 1 (CFHR1) Genotypes in Age-Related Macular Degeneration

, 2012
Rubén Martínez-Barricarte, Sergio Recalde, Patricia Fernández‐Robredo, Isabel Millán, Leticia Olavarrieta, Antonio Viñuela, Julián Pérez‐Pérez, Alfredo García‐Layana, Santiago Rodrı́guez de Córdoba   +8 more
openalex   +2 more sources