Results 191 to 200 of about 207,426 (323)

HAWK and HARRIER: Phase 3, Multicenter, Randomized, Double-Masked Trials of Brolucizumab for Neovascular Age-Related Macular Degeneration.

Ophthalmology (Rochester, Minn.), 2019
P. Dugel, A. Koh, Y. Ogura, G. Jaffe, U. Schmidt-Erfurth, David M. Brown, A. Gomes, J. Warburton, A. Weichselberger, F. Holz   +9 more
semanticscholar   +1 more source

Vascular disrupting agent for neovascular age related macular degeneration: a pilot study of the safety and efficacy of intravenous combretastatin a-4 phosphate [PDF]

, 2013
Mohamed Ibrahim, V. Diana, Yasir J. Sepah, Syed Mahmood Shah, Elizabeth Van Anden, Gulnar Hafiz, J. Kevin Donahue, Richard J. Rivers, Jai Balkissoon, James T. Handa, Peter A. Campochiaro, Quan Dong Nguyen   +11 more
openalex   +1 more source

Targeting ROCK1/YAP1 Axis Ameliorates Inflammation‐Induced Prostatic Hyperplasia via Stabilising SIRT1‐Dependent Mitochondrial Dynamics

Cell Proliferation, EarlyView.
Prostate‐specific YAP1 overexpression induces pathological BPH phenogenesis. Targeting ROCK1/YAP1 with fasudil and verteporfin alleviates inflammatory BPH lesions. YAP1 orchestrates mitochondrial dysfunction and oxidative stress via suppressing SIRT1 function.
Dongxu Lin, Pengyu Wei, Mengyang Zhang, Kang Li, Lina Li, Zhipeng Li, Changcheng Luo, Wenbo Kuang, Kai Cui, Zhong Chen   +9 more
wiley   +1 more source

Drug Delivery Technologies for the Treatment of Age-Related Macular Degeneration. [PDF]

Adv Sci (Weinh)
Rodriguez-Cruz JJ, Cutrufello J, Lam M, Nallaparaju S, Peppas NA.   +4 more
europepmc   +1 more source

Effects of photodynamic therapy on subfoveal blood flow in neovascular age-related macular degeneration patients [PDF]

, 2009
V. Vinh Moreau-Gaudry, Martial Geiser, J.P. Romanet, Ruxandra Hera, Julie Millet, Christophe Chiquet   +5 more
openalex   +1 more source

The fc fragment of IgMs binds C1q to activate the first step of the classical complement pathway, while inhibiting complement‐dependent cytotoxicity

The FEBS Journal, EarlyView.
Multimeric IgM‐fragment crystallizable region (Fc) fragments retain the ability to bind C1q and initiate the classical complement pathway, leading to C4 activation and deposition in vitro. However, the Fc cores can also inhibit complement‐dependent cytotoxicity by competing with surface‐bound antibodies for C1q engagement.
Andrea J. Pinto, Anne Chouquet, Isabelle Bally, Véronique Rossi, Nicole M. Thielens, Chantal Dumestre‐Pérard, Renate Kunert, Christine Gaboriaud, Wai Li Ling, Jean‐Baptiste Reiser   +9 more
wiley   +1 more source

Efficacy and Safety of Intravitreal Faricimab in Age-Related Macular Degeneration-A Review. [PDF]

J Clin Med
Chan CC, Liu PK, Cheng KC, Lai HC, Chang YC.   +4 more
europepmc   +1 more source

An international classification and grading system for age-related maculopathy and age-related macular degeneration

, 1995
A. Bird, N. Bressler, S. Bressler, I. Chisholm, G. Coscas, M. Davis, P. D. Jong, C. Klaver, B. Klein, R. Klein, P. B. Mitchell, J. Sarks, S. Sarks, G. Soubrane, H. Taylor, J. Vingerling   +15 more
semanticscholar   +1 more source

The association between neovascular age-related macular degeneration and regulatory T cells in peripheral blood

, 2015
Christopher Fugl Madelung, Mads Krüger Falk, Torben Lykke Sørensen   +2 more
openalex   +2 more sources

A Realist Evaluation of the Implementation and Use of Patient‐Reported Outcomes in Four Value‐Based Healthcare Programmes

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To investigate what works when using Patient‐Reported Outcome Measures (PROMs), for whom, in what contexts, and why in four Value‐Based Healthcare (VBHC) programmes. Design Realist evaluation. Methods Evaluation of Heart Failure, Parkinson's Disease, Epilepsy and Cataract surgery programmes using data from a scoping review, documentary ...
Mayara S. Bianchim, Ellie Crane, Leah McLaughlin, Carys Stringer, Gareth Roberts, Adele Cahill, Jane Noyes   +6 more
wiley   +1 more source