Results 201 to 210 of about 134,167 (281)

Protective Effects of Bone Mineral Density on Age-Related Macular Degeneration: A Mendelian Randomization Study. [PDF]

Int J Endocrinol
Sun Y, Huang J, Zhang Z, Chen Z, Li Z, Wu F, Wang Z, Wu T, Yi G, Meng F, Wu S.   +10 more
europepmc   +1 more source

Bridging the Social Gap Through ‘Conscious Caring’: A Constructivist Grounded Theory of the Art of Caring for Older Adults With Dual Sensory Impairment

Journal of Advanced Nursing, Volume 82, Issue 6, Page 6386-6400, June 2026.
ABSTRACT Aim The aim of this study was to develop a conceptual understanding of the role of caring for older adults with combined vision and hearing impairment (DSI). Background Dual sensory impairment (DSI) impacts both listening and speechreading communication, function and social participation, meaning that older adults often require support and ...
Moira E. Dunsmore, Julie Schneider, Heather Mckenzie, James A. Gillespie   +3 more
wiley   +1 more source

Deep learning in geographic atrophy: rethinking age-related macular degeneration progression and treatment. [PDF]

Ann Transl Med
Shiromani S, Chhablani J.
europepmc   +1 more source

Dual Knockout Models of the Spatially and Functionally Conserved rgra and rgrb Zebrafish Genes Reveal the Requirement of RGR for the Integrity of Cone‐Mediated Photopic Vision, the Photopic Visual Cycle and Bruch's Membrane Morphology

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
This study investigates the role of the vision gene RGR using novel dual knockout zebrafish models. The loss of rgra and rgrb results in zebrafish larvae having reduced visual function and altered retinoid profiles under light but not dark conditions. The OKR phenotype is enhanced under higher light intensities.
Grace Ruddin, Tess McCann, Joanna J. Kaylor, Michelle M. Fox, John D. Fehilly, Rebecca Ward, Adam Faulkner, Ailís L. Moran, Kieran Wynne, Roxana A. Radu, Michael G. Monaghan, Stephen D. Thorpe, Gabriel H. Travis, Breandán N. Kennedy   +13 more
wiley   +1 more source

Role of B Vitamins in Preventing the Development and Progression of Age-Related Macular Degeneration. [PDF]

Ophthalmol Ther
Poteet J, Koetting C, Vakharia PS.
europepmc   +1 more source

Dopamine D2 Receptor Agonists as Modulators of VEGF‐A‐Driven Angiogenesis: Mechanisms, Clinical Evidence, and Translational Opportunities

The FASEB Journal, Volume 40, Issue 9, 15 May 2026.
Interplay between VEGF‐A‐driven angiogenesis and DRD2‐mediated inhibition. Tumor‐derived VEGF‐A activates VEGFR2 on endothelial cells, triggering proangiogenic signaling pathways that promote abnormal vessel growth and vascular leakage. VEGF‐A also induces DRD2 expression, establishing a feedback mechanism.
Venu Akkanapally, Aman Kumar, Inemai Ezhil, Manas Ranjan Sahu, Xue‐Feng Bai, Kamal S. Pohar, Sujit Basu   +6 more
wiley   +1 more source

The gut-retina axis in age-related macular degeneration: immune crosstalk and metabolite production. [PDF]

Exp Biol Med (Maywood)
Zhou B, Parekh Z, Phung C, Rodriguez SH, Skondra D.   +4 more
europepmc   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, Volume 16, Issue 5, Page 857-869, May 2026.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Pharmacotherapy for Age-Related Macular Degeneration

Journal of Ophthalmic & Vision Research, 2008
Hamid Ahmadieh
doaj  

Drusen-specific dark adaptation profiles in intermediate age-related macular degeneration. [PDF]

Int J Retina Vitreous
Forte P, Ferro Desideri L, Nassisi M, Milanesi F, Feo A, Bagnasco I, Iglesia SM, Forte G, Scandella D, Roccatagliata F, Fontana V, Eandi CM, Iester M, Jolly JK, Zinkernagel MS, Viola F, Nicolò M.   +16 more
europepmc   +1 more source