Results 191 to 200 of about 93,339 (287)

Statins and Fibrates in Age-Related Macular Degeneration: A Contemporary Clinical Narrative Review (2020-2025). [PDF]

J Clin Med
Dmoch W, Sawicka J, Żelichowska N, Kępczyńska Z, Maciejewicz P, Kęcik D.   +5 more
europepmc   +1 more source

Applying Bayesian Multivariable Mendelian Randomisation to Prioritise Candidate Causal Traits From High‐Dimensional Data: Illustration From Estimation of the Effect of Maternal Metabolites on Offspring Birthweight

Genetic Epidemiology, Volume 50, Issue 6, September 2026.
ABSTRACT Mendelian randomisation (MR) is an approach to causal inference that uses genetic variants to infer whether or not a causal effect exists, unbiased by unobserved confounding. MR estimation usually considers the effect of a single exposure on an outcome; it has recently been extended to explore potential effects of multiple exposures using ...
Ciarrah‐Jane Barry, Verena Zuber, Deborah A. Lawlor, Maria Carolina Borges, Eleanor Sanderson, Chin Yang Shapland   +5 more
wiley   +1 more source

Novel Clinical Trial Designs for Intermediate Age-Related Macular Degeneration. [PDF]

Ophthalmol Sci
Berni A, Shen M, Liu J, Kastner JD, El-Mulki OS, Beqiri S, Herrera G, Trivizki O, Waheed NK, Usner DW, Levy B, O'Brien R, Gregori G, Rosenfeld PJ.   +13 more
europepmc   +1 more source

Lung Pericytes: Molecular Mechanisms, Signaling Pathways, and Roles in Pulmonary Diseases

Comprehensive Physiology, Volume 16, Issue 4, August 2026.
Central role of pericytes across major pulmonary diseases. Conceptual wheel diagram illustrating the central role of lung pericytes across diverse pulmonary disease states. A pericyte positioned at the center expresses canonical markers, including PDGFRβ, CD146, and NG2, and connects radially to five major disease contexts.
Stuti Agarwal, Anuradha Bankar, Vinicio A. de Jesus Perez   +2 more
wiley   +1 more source

Durability of Three Monthly Loading Doses with Faricimab in Treatment-Naïve Neovascular Age-Related Macular Degeneration. [PDF]

Ophthalmol Ther
Turan L, Bjerager J, Subhi Y, Klefter ON, Hajari JN, Schneider M.   +5 more
europepmc   +1 more source

Barriers to Ophthalmologic Care Reported by Family Caregivers of Users and Non‐Users With Intellectual Disabilities

Journal of Intellectual Disability Research, Volume 70, Issue 8, Page 845-857, August 2026.
ABSTRACT Background People with intellectual disabilities (IDs) are more likely to experience vision‐related impairments, yet they face many barriers to accessing eye care. Although previous studies have described these barriers, few have compared barriers reported by families who have and have not accessed ophthalmologic care, which may provide ...
Chiun‐Ho Hou, Yueh‐Ching Chou, Shu‐Fang Shih, Christy Pu   +3 more
wiley   +1 more source

Association Between PCSK9 Inhibitor Use and Risk of Age-Related Macular Degeneration. [PDF]

Transl Vis Sci Technol
Tsai CY, Weng CH, Tsai CY, Sheen YJ, Chen JP, Chen HM, Wang IJ, Chou CC.   +7 more
europepmc   +1 more source

Unravelling the Significance of Cystatin C and Bunina Bodies in Amyotrophic Lateral Sclerosis Pathogenesis

Neuropathology and Applied Neurobiology, Volume 52, Issue 4, August 2026.
ABSTRACT Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND), is a fatal neurodegenerative disease primarily affecting motor neurons. Two key protein inclusions found in lower motor neurons serve as neuropathological hallmarks of the disease in human tissue: the TDP43‐positive inclusion and the cystatin C‐positive Bunina body.
Sarah M. Granger, Rosemary A. Staniforth, Asbjorg Osk Snorradottir, Johnathan Cooper‐Knock, Kurt J. De Vos, J. Robin Highley   +5 more
wiley   +1 more source

Phosphorescent Iridium Hydrazinonicotinic Acid (HYNIC) Complexes That Bind to Prostate Specific Membrane Antigen: Potential Photodynamic Therapy of Prostate Cancer

Chemistry – A European Journal, Volume 32, Issue 25, 2 July 2026.
A phosphorescent iridium(III) complex has been prepared with a 6‐hydrazinonicotinic acid (HYNIC) ligand tethered to a lysine‐ureido‐glutamatic acid pharmacophore, which binds to an enzyme, called prostate‐specific membrane antigen (PSMA), which is overexpressed in prostate cancer.
La'El Kimchi, Emily R. McGowan, Katherine A. Morgan, Jonathan M. White, Trevor A. Smith, Stacey E. Rudd, Paul S. Donnelly   +6 more
wiley   +1 more source

Real-World Persistence with Anti-VEGF Therapy in Neovascular Age-related Macular Degeneration. [PDF]

Ophthalmol Ther
Elham A, Liu H, Li W, Zhao J, Yang X, Zeng C, Meng X.   +6 more
europepmc   +1 more source