Results 221 to 230 of about 93,339 (287)
Repeatability of SpotChecks contrast sensitivity test in macular disease
ABSTRACT Purpose SpotChecks is an accessible contrast sensitivity test with good repeatability in healthy adults. This study compared its intra‐visit repeatability with the near Pelli–Robson test in adults with macular disease. Methods One eye from 29 adults with macular disease (mean age 71 ± 13 years) underwent high‐contrast logMAR acuity and two ...
Katlyn B. Sprague +4 more
wiley +1 more source
TREM2 in age-related macular degeneration: a microglia-centered perspective in the retinal myeloid landscape. [PDF]
Zhu S, Yang T, Sheng L, Shi L.
europepmc +1 more source
Integrated Population Pharmacokinetic Analysis of Intravitreal Aflibercept Drug Products
ABSTRACT Neovascular age‐related macular degeneration (nAMD) and diabetic macular edema (DME) can cause substantial vision loss. The 2‐mg drug product of aflibercept (AFL‐2)—an anti‐vascular endothelial growth factor agent—has established efficacy and safety in both diseases.
Sébastien Bihorel +10 more
wiley +1 more source
Two-Year Real-World Outcomes of Faricimab in Treatment-Resistant Neovascular Age-Related Macular Degeneration. [PDF]
Ahmed E +3 more
europepmc +1 more source
This study evaluates the clinical efficacy of Nd:YAG laser membranotomy in dogs with fibrin membrane‐induced pupillary block (FMPB). Targeted application of the Nd:YAG laser safely disrupts the obstructive pupillary membrane, thereby restoring normal aqueous humour outflow and effectively resolving secondary intraocular pressure (IOP) elevation without
Haerin Yoon +6 more
wiley +1 more source
The Role of Kynurenine and 5-Hydroxytryptophan in Modulating Microbiota and Their Implications in Exudative Age-Related Macular Degeneration. [PDF]
Vilkeviciute-Petraite A +7 more
europepmc +1 more source
This study maps age‐aligned cochlear and vestibular decline in SAMP8 mice, linking functional impairment with synaptic vulnerability, mitochondrial ultrastructural injury, and autophagy/mitophagy–lysosome transcriptional remodeling. The findings provide an integrated framework for understanding shared inner‐ear aging trajectories.
Jingyi Xie +14 more
wiley +1 more source
Machine-learning for age-related macular degeneration using multimodal fundus data. [PDF]
Li M +6 more
europepmc +1 more source
Is IL-10 a Good Target to Inhibit Choroidal Neovascularisation in Age-Related Macular Disease?
Sue Lightman +3 more
core +1 more source

