Results 31 to 40 of about 207,426 (323)

Detection of early age-related macular degeneration using novel functional parameters of the focal cone electroretinogram [PDF]

, 2014
The focal cone electroretinogram is a sensitive marker for macular disease, but have we unlocked its full potential? Typically assessment of waveform parameters is subjective and focuses on a small number of locations (e.g. the a-wave).
A Bird, A Fulton, A Vincent, AA Paupoo, AE Mentzer, Alison Mary Binns, AM Binns, Ashley Wood, B Falsini, B Falsini, B Lei, BJ Fowler, C Bunce, C Friedburg, C Gerth, C Westall, DC Hood, DC Hood, H Asi, H Nishihara, H Terasaki, J Ambati, J Bland, J Sunness, JA Hanley, JF Remulla, JK Chylack LT Wolfe, K Neelam, KE Mortlock, M Bach, M Gur, M Piccardi, M Sandberg, M Sandberg, ME Breton, N Peachey, N Wali, P Lachapelle, P Walter, R Granit, R Shiells, RA Bush, RE Hogg, Thomas Margrain, TY Wong, Y Miyake, Zsolt Ablonczy   +46 more
core   +15 more sources

Age-Related Macular Degeneration: Classification and Pathogenesis

Türk Oftalmoloji Dergisi, 2014
Age-related macular degeneration (AMD) was first described in 1885 by Otto Haab as a disease in patients above 50 years of age with progressive retinal pigment epithelial and atrophic degenerations of the macula reducing the central visual acuity.
İmren Akkoyun
doaj   +1 more source

RETINAL ANGIOMATOUS PROLIFERATION: A Quantitative Analysis of the Fundoscopic Features of the Fellow Eye [PDF]

, 2015
PURPOSE: To quantitatively analyze and compare the fundoscopic features between fellow eyes of retinal angiomatous proliferation and typical exudative age-related macular degeneration and to identify possible predictors of neovascularization. METHODS:
Costa, MA, da Luz Cachulo, M, Figueira, MJ, Laíns, I, Marques, JP, Pires, I, Silva, R   +6 more
core   +1 more source

Intravitreal aflibercept in neovascular age-related macular degeneration previously treated with ranibizumab

International Journal of Ophthalmology, 2017
AIM: To report the change in visual acuity and central macular thickness (CMT) following treatment with intravitreal aflibercept injections in patients with neovascular age-related macular degeneration (nAMD) with suboptimum response to ranibizumab ...
Rachel Hui Fen Lim, Bhaskar Gupta, Peter Simcock   +2 more
doaj   +1 more source

Plasma 25-Hydroxyvitamin-D (25-OHD) levels and late-stage age-related macular degeneration (AMD): Assessing the correlation

JKKI (Jurnal Kedokteran dan Kesehatan Indonesia), 2022
Background: Age-related Macular Degeneration (AMD) is a degenerative disease caused by multiple factors, including inflammation. This condition may lead to irreversible macular damage.
Supanji Supanji, Dewi Fathin Romdhoniyyah, Ayudha Bahana Ilham Perdamaian, Anindita Dianratri, Muhammad Bayu Sasongko, Angela Nurini Agni, Tri Wahyu Widayanti, Firman Setya Wardhana, Dian Caturini Sulistyaningrum, Mohammad Eko Prayogo, Masashi Kawaichi, Chio Oka   +11 more
doaj   +1 more source

Primary prevention of age related macular degeneration. [PDF]

, 2007
Current evidence does not support a protective role for dietary antioxidant ...
Evans, Jennifer
core   +2 more sources

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

Nature Genetics, 2015
Advanced age-related macular degeneration (AMD) is the leading cause of blindness in the elderly, with limited therapeutic options. Here we report on a study of >12 million variants, including 163,714 directly genotyped, mostly rare, protein-altering ...
F. Grassmann, Shritoma Sengupta
semanticscholar   +1 more source

Pachychoroid neovasculopathy and age-related macular degeneration. [PDF]

, 2015
Pachychoroid neovasculopathy is a recently proposed clinical entity of choroidal neovascularization (CNV). As it often masquerades as neovascular age-related macular degeneration (AMD), it is currently controversial whether pachychoroid neovasculopathy ...
Akagi-Kurashige, Yumiko, Miyake, Masahiro, Nakanishi, Hideo, Oishi, Akio, Ooto, Sotaro, Takahashi, Ayako, Tamura, Hiroshi, Tsujikawa, Akitaka, Ueda-Arakawa, Naoko, Yamashiro, Kenji, Yoshikawa, Munemitsu, Yoshimura, Nagahisa   +11 more
core   +1 more source

The role of oxidative stress and antioxidants in the pathogenesis of age-related macular degeneration

Clinics, 2011
OBJECTIVE: To investigate the role of oxidant/antioxidant status and protein oxidation in the development of age-related macular degeneration. METHOD: The activities of serum superoxide dismutase and glutathione peroxidase and the levels of serum ...
Zuhal Yildirim, Nil Irem Ucgun, Filiz Yildirim   +2 more
doaj   +1 more source

Beyond the Complement Cascade: Insights into Systemic Immunosenescence and Inflammaging in Age-Related Macular Degeneration and Current Barriers to Treatment

Cells, 2023
Landmark genetic studies have revealed the effect of complement biology and its regulation on the pathogenesis of age-related macular degeneration (AMD).
Adnan H. Khan, Itay Chowers, Andrew J. Lotery   +2 more
doaj   +1 more source