Results 31 to 40 of about 474,048 (356)
Background Our objective was to explore what people receiving and providing care consider to be ‘good’ in-home care for people living with dementia. Methods We conducted 36 in-depth interviews and two focus groups with key stakeholders in Australia in ...
Anita M. Y. Goh +20 more
doaj +1 more source
Background Patient-reported outcome measures (PROMs) provide a measure of self-perceived health status or health-related quality of life. They have been used to support provider-patient decisions, healthcare delivery, and value-based healthcare models. A
David A Snowdon +6 more
doaj +1 more source
Over the last decade, the African turquoise killifish, Nothobranchius furzeri, has emerged as an important model system for the study of vertebrate biology and ageing.
Luca Dolfi +3 more
doaj +1 more source
The impact of E-cigarette vaping and vapour constituents on bone health
Background In contrast to cigarettes, electronic cigarette use (E-cigarettes) has grown substantially over the last decade. This is due to their promotion as both a safer alternative to cigarettes and as an aide to stop smoking.
Thomas Nicholson +3 more
doaj +1 more source
ABSTRACT Background Pediatric patients with extracranial solid tumors (ST) receiving chemotherapy are at an increased risk for Pneumocystis jirovecii pneumonia (PJP). However, evidence guiding prophylaxis practices in this population is limited. A PJP‐related fatality at our institution highlighted inconsistent prescribing approaches and concerns about
Kriti Kumar +8 more
wiley +1 more source
Dynamic lipidome alterations associated with human health, disease and ageing
Lipids can be of endogenous or exogenous origin and affect diverse biological functions, including cell membrane maintenance, energy management and cellular signalling.
Daniel Hornburg +16 more
semanticscholar +1 more source
Sickle Cell Disease Is an Inherent Risk for Asthma in a Sibling Comparison Study
ABSTRACT Introduction Sickle cell disease (SCD) and asthma share a complex relationship. Although estimates vary, asthma prevalence in children with SCD is believed to be comparable to or higher than the general population. Determining whether SCD confers an increased risk for asthma remains challenging due to overlapping symptoms and the ...
Suhei C. Zuleta De Bernardis +9 more
wiley +1 more source
ABSTRACT Background While Wilms tumor (WT) typically has a favorable prognosis, relapsed cases—especially those with high‐risk histology—remain therapeutically challenging after intensive frontline therapy. The combination of vincristine and irinotecan has demonstrated activity in pediatric solid tumors, and pazopanib, a multi‐targeted tyrosine kinase ...
Maria Debora De Pasquale +6 more
wiley +1 more source
Mondo complexes regulate TFEB via TOR inhibition to promote longevity in response to gonadal signals
Removal of the C. elegans germline substantially increases organismal lifespan. Here, Nakamura et al. show that the transcription factors MML-1 and MXL-2 coordinate this process in that they reduce TOR signalling and increase autophagy by regulating ...
Shuhei Nakamura +9 more
doaj +1 more source
Building Face Ageing Model Using Face Synthesis
Advancements in face synthesis technology have enabled innovative methods for modeling facial aging. This research paper focuses primarily on creating a robust face aging model using deep learning and Generative Adversarial Networks (GANs), trained on a ...
Shraddha Mishra +2 more
semanticscholar +1 more source

