Results 111 to 120 of about 14,614 (302)
Challenges of overcoming ageism towards elderly people in healthcare context
Horyzonty Wychowania, 2018 RESEARCH OBJECTIVE: The purpose of the paper is to analyse the impact ageism may have on providing healthcare to elderly people. THE RESEARCH PROBLEM AND METHODS: The article investigates the consequences of ageism in medical settings, where the elderly
Iwona Nowakowska
doaj
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
HeliyonBackground: Although ageism has a strong relationship with attitudes toward dementia, no study has confirmed how person-centered care and compassion mediate the relationship between nursing students’ ageism and attitudes toward dementia. Objectives: This
HeeKyung Chang +2 more
doaj +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
, 2018 This paper focuses on research in the field of gerontology, specifically ageism and discrimination on the basis of one's ...
MaKenzie R. Johnson
core +2 more sources
Nurse Media: Journal of NursingBackground: Ageism negatively impacts older adults’ health, especially in long-term care facilities (LTCFs), where healthcare workers often hold unfavorable views of them. Understanding these perspectives is vital for combating ageism and improving LTCF
Dianis Wulan Sari +5 more
doaj +1 more source
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Understanding ageism in the workplace
An ageing society and workforce present both challenges and opportunities. The presence of multiple generations in the workplace can lead to age-related tensions, with some workers considered “too young” and others “too old”.
Esteves, C.S. +4 more
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