Results 121 to 130 of about 211,860 (282)
Molecular Mechanisms Underlying Accelerated Aging by Defects in the FGF23-Klotho System
The basic research of aging has been primarily focused on elucidating mechanisms of aging and longevity that are evolutionarily conserved from yeasts to primates.
Makoto Kuro-o
doaj +1 more source
Lithium plating mechanisms on 2D‐coated current collectors: PtTe2 coating enables rapid Li surface diffusivity, while PdTe2 and NiTe2 coatings shorten diffusion paths for Li adatoms. In addition, Li2Te, formed from PdTe2 and NiTe2 decomposition, reduces the critical nucleus size by lowering the interfacial energy between the electrolyte and deposited ...
Chae Yoon Im+4 more
wiley +1 more source
Lack of telomerase reduces cancer incidence and increases lifespan of zebrafish tp53 M214K mutants
Telomerase activity is restricted in humans and telomere attrition occurs in several tissues accompanying natural aging. Critically short telomeres trigger DNA damage responses and activate p53 which leads to apoptosis or replicative senescence.
Naz Şerifoğlu+2 more
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Premature ageing and glomerulonephritis [PDF]
Ian More+2 more
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Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi+4 more
wiley +1 more source
To determine whether transplanted amniotic membrane mesenchymal stem cells (AMSCs) ameliorated the premature senescent phenotype of Bmi-1-deficient mice, postnatal 2-day-old Bmi-1−/− mice were injected intraperitoneally with the second-passage AMSCs from
Chunfeng Xie+5 more
doaj +1 more source
Etiology and Management of Sexual Dysfunction [PDF]
Sexual dysfunction is the impairment or disruption of any of the three phases of normal sexual functioning, including loss of libido, impairment of physiological arousal and loss, delay or alteration of orgasm.
Bevinahalli Nanjegowda, Raveesh+5 more
core +2 more sources
Biology of premature ageing in survivors of cancer
Over 30 million cancer survivors exist worldwide. Survivors have an earlier onset and higher incidence of chronic comorbidities, including endocrinopathies, cardiac dysfunction, osteoporosis, pulmonary fibrosis, secondary cancers and frailty than the general population; however, the fundamental basis of these changes at the cellular level is unknown ...
Margaret C. Cupit-Link+8 more
openaire +3 more sources
Designing Moderately‐Solvating Electrolytes for High‐Performance Lithium–Sulfur Batteries
The design principle of moderately solvating electrolytes (MSEs) for lithium–sulfur batteries (LSBs) is demonstrated by using a multiple‐solvent system comprising of a highly‐solvating solvent, a weakly‐solvating solvent, and a non‐solvating solvent. The optimal MSE significantly improves the cycle life of LSBs by doubling that of similar cells with ...
David J. Kautz+22 more
wiley +1 more source
To inform rational therapeutics to alleviate many senescence-related diseases in terms of the pathogenic pathways, we investigated the protective mechanisms of TLH-3 against premature senescence in tert-butyl hydroperoxide (t-BHP)-induced human embryonic
Wen-Juan Pan+9 more
doaj