Results 61 to 70 of about 7,411 (204)

Learning and memory in agmatine-treated rats [PDF]

open access: yesPharmacology Biochemistry and Behavior, 2002
Agmatine, a noncompetitive N-methyl-D-aspartate (NMDA) antagonist, was examined for its role in water maze place learning, contextual and auditory-cued (discrete) fear learning and conditioned taste aversion learning, when administered systemically.
B E, McKay   +4 more
openaire   +2 more sources

Sputum agmatine measurements.

open access: yes, 2014
(A) Distribution of agmatine concentration in 197 human sputum samples as measured by UPLC-MS/MS. (B) Sputum agmatine values during illness. Medians, 1st and 3rd quartiles and range within 1.5 times the quartiles shown by thick bars, boxes and whiskers ...
Nick B. Paulson (650497)   +8 more
core   +1 more source

Agmatine for Pain Management in Dogs With Coxofemoral Joint Osteoarthritis: A Pilot Study

open access: yesFrontiers in Veterinary Science, 2018
Background: Pain from coxofemoral joint (CFJ) osteoarthritis (OA) characteristic of canine hip dysplasia (CHD) afflicts many dogs. Intervertebral disc (IVD) degeneration is a common CFJ OA comorbidity.
Takashi Taguchi   +6 more
doaj   +1 more source

Neuroprotective Role of E3 Ubiquitin Ligase TRIM2 in Parkinson's Disease: Attenuation of Oxidative Stress and Apoptosis via Promoting ELAVL1 Ubiquitination

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
The E3 ubiquitin ligase TRIM2 confers neuroprotection against 6‐OHDA‐induced oxidative stress and apoptosis. It exerts this function by binding to ELAVL1 and promoting its degradation via the ubiquitin‐proteasome pathway. Thus, our study reveals the TRIM2‐ELAVL1 axis as a key regulatory mechanism for neuronal survival under 6‐OHDA‐stimulated toxic ...
Wei Liang   +4 more
wiley   +1 more source

Neuroprotective Role of Agmatine in Neurological Diseases [PDF]

open access: yesCurrent Neuropharmacology, 2018
Neurological diseases have always been one of the leading cause of mobility and mortality world-widely. However, it is still lacking efficient agents. Agmatine, an endogenous polyamine, exerts its diverse biological characteristics and therapeutic potential in varied aspects.This review would focus on the neuroprotective actions of agmatine and its ...
Xu, Weilin   +4 more
openaire   +2 more sources

Agmatina, um candidato à adjuvante da farmacoterapia da depressão: estudos in vitro e in vivo [PDF]

open access: yes, 2014
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-graduação em Bioquímica, Florianópolis, 2014A agmatina é um neuromodulador, cuja atividade antidepressiva tem sido mostrada tanto em ensaios pré ...
Freitas, Andiara Espíndola de
core  

A review on agmatine as a novel neurotransmitterneuromodulator

open access: yesJournal of Marmara University Institute of Health Sciences, 2013
Agmatine, an endogenous amine, which is formed by decarboxylation of L-arginine, a semi essential amino acid, by arginine decarboxylase (ADC) and degraded by agmatinase can be defined as a putative neurotransmitter/neuromodulator. Agmatine is widely distributed in the body except from brain. Agmatine binds to alpha-adrenergic and imidazoline receptors,
GÜMRÜ, Salih   +2 more
openaire   +2 more sources

Deep Understanding of Vaginal Microbiota in HPV‐Related Diseases From a Multi‐Omics Perspective

open access: yesVIEW Medicine, Volume 1, Issue 1, August 2026.
Current understanding of the vaginal microbiota and roles of critical vaginal bacteria, including Lactobacillus and anaerobic pathogens, in human papillomavirus (HPV) infection and HPV‐related diseases from a multi‐omics perspective. ABSTRACT There is a large number of microorganisms in the human body, which are inseparable from human health.
Jianxujie Zheng   +3 more
wiley   +1 more source

Agmatine, by Improving Neuroplasticity Markers and Inducing Nrf2, Prevents Corticosterone-Induced Depressive-Like Behavior in Mice

open access: yes, 2015
Agmatine, an endogenous neuromodulator, is a potential candidate to constitute an adjuvant/monotherapy for the management of depression. A recent study by our group demonstrated that agmatine induces Nrf2 and protects against corticosterone effects in a ...
García Lopez, Manuela   +2 more
core   +1 more source

The Fungal Pathogen Fusarium graminearum Can Hydrolyse Tryptamine‐Derived Hydroxy‐Cinnamic Acid Amide Defence Compounds, and Generates Highly Increased Auxin Levels in Wheat via Copper Amine‐Oxidases

open access: yesMolecular Plant Pathology, Volume 27, Issue 8, August 2026.
Fusarium graminearum can cleave tryptamine‐derived hydroxycinnamic acid amides and convert the released tryptamine into auxin, suppressing plant defence responses; aoxΔ7—septuple knockout of copper amine oxidases blocks auxin formation. ABSTRACT The important cereal pathogen Fusarium graminearum is not only able to produce trichothecene toxins, like ...
Thomas Svoboda   +12 more
wiley   +1 more source

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