Results 61 to 70 of about 7,411 (204)
Learning and memory in agmatine-treated rats [PDF]
Agmatine, a noncompetitive N-methyl-D-aspartate (NMDA) antagonist, was examined for its role in water maze place learning, contextual and auditory-cued (discrete) fear learning and conditioned taste aversion learning, when administered systemically.
B E, McKay +4 more
openaire +2 more sources
(A) Distribution of agmatine concentration in 197 human sputum samples as measured by UPLC-MS/MS. (B) Sputum agmatine values during illness. Medians, 1st and 3rd quartiles and range within 1.5 times the quartiles shown by thick bars, boxes and whiskers ...
Nick B. Paulson (650497) +8 more
core +1 more source
Agmatine for Pain Management in Dogs With Coxofemoral Joint Osteoarthritis: A Pilot Study
Background: Pain from coxofemoral joint (CFJ) osteoarthritis (OA) characteristic of canine hip dysplasia (CHD) afflicts many dogs. Intervertebral disc (IVD) degeneration is a common CFJ OA comorbidity.
Takashi Taguchi +6 more
doaj +1 more source
The E3 ubiquitin ligase TRIM2 confers neuroprotection against 6‐OHDA‐induced oxidative stress and apoptosis. It exerts this function by binding to ELAVL1 and promoting its degradation via the ubiquitin‐proteasome pathway. Thus, our study reveals the TRIM2‐ELAVL1 axis as a key regulatory mechanism for neuronal survival under 6‐OHDA‐stimulated toxic ...
Wei Liang +4 more
wiley +1 more source
Neuroprotective Role of Agmatine in Neurological Diseases [PDF]
Neurological diseases have always been one of the leading cause of mobility and mortality world-widely. However, it is still lacking efficient agents. Agmatine, an endogenous polyamine, exerts its diverse biological characteristics and therapeutic potential in varied aspects.This review would focus on the neuroprotective actions of agmatine and its ...
Xu, Weilin +4 more
openaire +2 more sources
Agmatina, um candidato à adjuvante da farmacoterapia da depressão: estudos in vitro e in vivo [PDF]
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-graduação em Bioquímica, Florianópolis, 2014A agmatina é um neuromodulador, cuja atividade antidepressiva tem sido mostrada tanto em ensaios pré ...
Freitas, Andiara Espíndola de
core
A review on agmatine as a novel neurotransmitterneuromodulator
Agmatine, an endogenous amine, which is formed by decarboxylation of L-arginine, a semi essential amino acid, by arginine decarboxylase (ADC) and degraded by agmatinase can be defined as a putative neurotransmitter/neuromodulator. Agmatine is widely distributed in the body except from brain. Agmatine binds to alpha-adrenergic and imidazoline receptors,
GÜMRÜ, Salih +2 more
openaire +2 more sources
Deep Understanding of Vaginal Microbiota in HPV‐Related Diseases From a Multi‐Omics Perspective
Current understanding of the vaginal microbiota and roles of critical vaginal bacteria, including Lactobacillus and anaerobic pathogens, in human papillomavirus (HPV) infection and HPV‐related diseases from a multi‐omics perspective. ABSTRACT There is a large number of microorganisms in the human body, which are inseparable from human health.
Jianxujie Zheng +3 more
wiley +1 more source
Agmatine, an endogenous neuromodulator, is a potential candidate to constitute an adjuvant/monotherapy for the management of depression. A recent study by our group demonstrated that agmatine induces Nrf2 and protects against corticosterone effects in a ...
García Lopez, Manuela +2 more
core +1 more source
Fusarium graminearum can cleave tryptamine‐derived hydroxycinnamic acid amides and convert the released tryptamine into auxin, suppressing plant defence responses; aoxΔ7—septuple knockout of copper amine oxidases blocks auxin formation. ABSTRACT The important cereal pathogen Fusarium graminearum is not only able to produce trichothecene toxins, like ...
Thomas Svoboda +12 more
wiley +1 more source

