Arginine Decarboxylase Is Essential for Pneumococcal Stress Responses [PDF]
Pathogens, 2021 Polyamines such as putrescine, cadaverine, and spermidine are small cationic molecules that play significant roles in cellular processes, including bacterial stress responses and host–pathogen interactions.
Moses Ayoola +2 more
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Hydroxylamine Analogue of Agmatine: Magic Bullet for Arginine Decarboxylase [PDF]
Biomolecules, 2020 The biogenic polyamines, spermine, spermidine (Spd) and putrescine (Put) are present at micro-millimolar concentrations in eukaryotic and prokaryotic cells (many prokaryotes have no spermine), participating in the regulation of cellular proliferation and
Mervi Hyvönen +2 more
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Structural and biochemical characterisation of the Providencia stuartii arginine decarboxylase shows distinct polymerisation and regulation [PDF]
Communications Biology, 2022 Jessop et. al. investigate the expression, activity, structure and supramolecular assembly of the arginine decarboxylase from Providencia stuartii, compare its polymers with those formed by the Escherichia coli lysine decarboxylase, and analyse the ...
Matthew Jessop +10 more
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Simultaneous Silencing of Two Arginine Decarboxylase Genes Alters Development in Arabidopsis [PDF]
Frontiers in Plant Science, 2016 Polyamines (PAs) are small aliphatic polycations that are found ubiquitously in all organisms. In plants, PAs are involved in diverse biological processes such as growth, development, and stress responses.
Diana Sánchez-Rangel +2 more
exaly +4 more sources
Arginine Is a Novel Drug Target for Arginine Decarboxylase in Human Colorectal Cancer Cells [PDF]
International Journal of Molecular Sciences, 2023 Colorectal cancer (CRC) has been proven to be highly reliant on arginine availability. Limiting arginine-rich foods or treating patients with arginine-depleting enzymes arginine deiminase (ADI) or arginase can suppress colon cancer. However, arginase and
Lee Man Yuen +2 more
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High-level production of the agmatine in engineered Corynebacterium crenatum with the inhibition-releasing arginine decarboxylase [PDF]
Microbial Cell Factories, 2022 Background Agmatine is a member of biogenic amines and is an important medicine which is widely used to regulate body balance and neuroprotective effects.
Fengyu Yang +5 more
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Characterization of an Arginine Decarboxylase from Streptococcus pneumoniae by Ultrahigh-Performance Liquid Chromatography–Tandem Mass Spectrometry [PDF]
BiomoleculesPolyamines are polycations derived from amino acids that play an important role in proliferation and growth in almost all living cells. In Streptococcus pneumoniae (the pneumococcus), modulation of polyamine metabolism not only plays an important ...
Jung Hwa Lee +4 more
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SP_0916 Is an Arginine Decarboxylase That Catalyzes the Synthesis of Agmatine, Which Is Critical for Capsule Biosynthesis in Streptococcus pneumoniae [PDF]
Frontiers in Microbiology, 2020 The global burden of invasive pneumococcal diseases, including pneumonia and sepsis, caused by Streptococcus pneumoniae, a Gram-positive bacterial pathogen, remains a major global health risk.
Moses B. Ayoola +9 more
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Functional roles of ornithine decarboxylase and arginine decarboxylase during the peri-implantation period of pregnancy in sheep [PDF]
Journal of Animal Science and Biotechnology, 2018 Background Polyamines stimulate DNA transcription and mRNA translation for protein synthesis in trophectoderm cells, as well as proliferation and migration of cells; therefore, they are essential for development and survival of conceptuses (embryo/fetus ...
Yasser Y. Lenis +8 more
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Rationally Engineering pH Adaptation of Acid‐Induced Arginine Decarboxylase from Escherichia coli to Alkaline Environments to Efficiently Biosynthesize Putrescine [PDF]
Advanced ScienceAcid‐induced arginine decarboxylase AdiA is a typical homo‐oligomeric protein biosynthesizing alkaline nylon monomer putrescine. However, upon loss of the AdiA decamer oligomeric state at neutral and alkaline conditions the activity also diminishes ...
Li Wang +4 more
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