Results 1 to 10 of about 7,411 (204)
Development of a Pseudomonas aeruginosa Agmatine Biosensor
Biosensors, 2014 Agmatine, decarboxylated arginine, is an important intermediary in polyamine production for many prokaryotes, but serves higher functions in eukaryotes such as nitric oxide inhibition and roles in neurotransmission.
Adam Gilbertsen, Bryan Williams
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The arginine decarboxylase pathways of host and pathogen interact to impact inflammatory pathways in the lung. [PDF]
PLoS ONE, 2014 The arginine decarboxylase pathway, which converts arginine to agmatine, is present in both humans and most bacterial pathogens. In humans agmatine is a neurotransmitter with affinities towards α2-adrenoreceptors, serotonin receptors, and may inhibit ...
Nick B Paulson +8 more
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THE EFFECT OF AGMATINE ON SPIKE-AND-WAVE DISCHARGES IN A GENETIC MODEL OF ABSENCE EPILEPSY
İstanbul Tıp Fakültesi Dergisi, 2022 Objective: Studies on the actions of exogenous agmatine in experimental models have shown its anti-convulsant effects. However, there are no findings regarding the influence of agmatine on absence epilepsy.
Özlem Akman +4 more
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Acid-sensing ion channel 3 is required for agmatine-induced histamine-independent itch in mice
Frontiers in Molecular Neuroscience, 2023 IntroductionItch is a common symptom of many skin and systemic diseases. Identifying novel endogenous itch mediators and the downstream signaling pathways involved will contribute to the development of new strategies for the treatment of chronic itch. In
Guo-Kun Zhou +11 more
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Psychiatry and Clinical Psychopharmacology, 2021 Objective: Agmatine, the decarboxylation product of arginine produced by arginine decarboxylase, is a novel neurotransmitter and exists in the mammalian brain.
Muge Sirvanci-Yalabik +3 more
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Agmatine Reduces Lipopolysaccharide-Mediated Oxidant Response via Activating PI3K/Akt Pathway and Up-Regulating Nrf2 and HO-1 Expression in Macrophages. [PDF]
PLoS ONE, 2016 Macrophages are key responders of inflammation and are closely related with oxidative stress. Activated macrophages can enhance oxygen depletion, which causes an overproduction of reactive oxygen species (ROS) and leads to further excessive inflammatory ...
Jianshen Chai +11 more
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Frontiers in Pharmacology, 2021 Background: Epilepsy is a common neurological disease, and neuroinflammation is one of the main contributors to epileptogenesis. Pyroptosis is a type of pro-inflammatory cell death that is related to epilepsy.
Xueying Li +8 more
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Beni-Suef University Journal of Basic and Applied Sciences, 2021 Background Drug withdrawal syndrome occurs due to abrupt cessation of an addictive substance. Dependence to diazepam can be manifested by withdrawal syndrome which may include symptoms such as irritability, psychosis, sleep disturbance, seizures, mood ...
Hira Rafi, Hamna Rafiq, Muhammad Farhan
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EFFECTS OF AGMATINE ON ACOUSTIC STARTLE REFLEX AND AUDITORY SYSTEM IN RATS
Malang Neurology Journal, 2021 Background: A polyamine, agmatine, has been proposed as a new neurotransmitter in the brain. Objective: The aim of this study was to evaluate the effects of acute and chronic agmatine treatment on the rat auditory system.
Özlem Saatci +2 more
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Transcriptome profiling of Lactococcus lactis subsp. cremoris CECT 8666 in response to agmatine
Genomics Data, 2016 The dairy strain Lactococcus lactis subsp. cremoris CECT 8666 (formerly GE2-14) synthesizes the biogenic amine putrescine from agmatine via the agmatine deiminase (AGDI) pathway [1]. The AGDI cluster of L.
Beatriz del Rio +7 more
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