Results 21 to 30 of about 7,411 (204)
Inhibition of agmatine transport in liver mitochondria by new charge-deficient agmatine analogues
Biochemical Society Transactions, 2007 The charge of the agmatine analogues AO-Agm [N-(3-aminooxypropyl)guanidine], GAPA [N-(3-aminopropoxy)guanidine] and NGPG [N-(3-guanidinopropoxy)guanidine] is deficient as compared with that of agmatine and they are thus able to inhibit agmatine transport in liver mitochondria.
GRILLO MA +7 more
openaire +5 more sources
Agmatine and agmatine analogs in the treatment of epilepsy, seizure, and electroconvulsive disorders [PDF]
, 2010 Pharmaceutical preparations containing of agmatine, congeners, analogs or derivatives thereof for use in preventing or treating epilepsy, seizures and other electroconvulsive disorders are provided.
CROOKS PETER A +2 more
core +3 more sources
Agmatine: A novel endogenous vasodilator substance
Life Sciences, 1995 The purpose of the study was to investigate the effects of agmatine, an endogenous clonidine-displacing substance (CDS), on systemic hemodynamics in the anesthetized rat. Bolus intravenous (i.v.) injections of agmatine decreased systemic arterial pressure (SAP) and systemic vascular resistance in a dose-dependent manner.
Y, Gao +6 more
openaire +3 more sources
Effect of agmatine on electrically and chemically induced seizures in mice
, 2021 Agmatine, an amine and organic cation, is formed by the decarboxylation of L-arginine by arginine decarboxylase. It binds to alpha(2)-adrenergic and imidazoline receptors.
Berkman, K +4 more
core +2 more sources
Agmatine: A potential Neurotherapeutic Agent [PDF]
, 2021 Agmatine, a natural polyamine disregarded almost for over 100 years, was discovered in year 1910. Almost after a decade, several researches on Agmatine indicated its modulatory action at multiple molecular targets such as, nitric oxide synthesis ...
Umekar, Milind +5 more
core +1 more source
Agmatine protects mitochondria in LPS-stimulated microglia
, 2021 Mitochondria play a key role in energy metabolism and regulate some of the principal cellular processes such as the production of ATP and reactive oxygen species, as well as a regulation of apoptotic cell death.
Božić, Iva +9 more
core +5 more sources
Agmatine Signaling: Odds and Threads [PDF]
Cardiovascular Drug Reviews, 2004 ABSTRACTAgmatine is a metabolite of L‐arginine. It is formed by the decarboxylation of L‐arginine via arginine decarboxylase in bacteria, plants and mammals. It is becoming clear that it has multiple physiological functions as a potential transmitter. Agmatine binds to α2‐adrenoceptors and to imidazoline binding sites.
Reinhard, Berkels +3 more
openaire +2 more sources
Guanidino acid hydrolysis by the human enzyme annotated as agmatinase
Scientific Reports, 2022 Guanidino acids such as taurocyamine, guanidinobutyrate, guanidinopropionate, and guanidinoacetate have been detected in humans. However, except for guanidionacetate, which is a precursor of creatine, their metabolism and potential functions remain ...
Malte Sinn +6 more
doaj +1 more source
The effect of agmatine on trichothecene type B and zearalenone production in Fusarium graminearum, F. culmorum and F. poae [PDF]
PeerJ, 2016 Agmatine and other putrescines are known for being strong inducers of deoxynivalenol (DON) production in Fusarium graminearum. Other important species produce DON and/or other trichothecene type B toxins (3 acetylated DON, 15 acetylated DON, Fusarenon-X,
Matias Pasquali +3 more
doaj +2 more sources
Structure and Biosynthesis of Mangotoxin Produced by the Plant Pathogen Pseudomonas syringae
Angewandte Chemie, EarlyView.The structure of mangotoxin remained elusive for over two decades. Here, mangotoxin was isolated from the native producer, Pseudomonas syringae pv. syringae, and was determined to be an alkyne‐containing dipeptide. Mangotoxin inhibited the growth of multidrug‐resistant human pathogen Klebsiella pneumoniae.
Alexis H. Murray +4 more
wiley +2 more sources