Results 11 to 20 of about 130,955 (165)

Bioinformatic evaluation of L-arginine catabolic pathways in 24 cyanobacteria and transcriptional analysis of genes encoding enzymes of L-arginine catabolism in the cyanobacterium Synechocystis sp. PCC 6803 [PDF]

BMC Genomics, 2007
Background So far very limited knowledge exists on L-arginine catabolism in cyanobacteria, although six major L-arginine-degrading pathways have been described for prokaryotes.
Pistorius Elfriede K, Staiger Dorothee, Rückert Christian, Schriek Sarah, Michel Klaus-Peter   +4 more
doaj   +2 more sources

Arginase and Arginine Decarboxylase - Where Do the Putative Gate Keepers of Polyamine Synthesis Reside in Rat Brain? [PDF]

PLoS ONE, 2013
Polyamines are important regulators of basal cellular functions but also subserve highly specific tasks in the mammalian brain. With this respect, polyamines and the synthesizing and degrading enzymes are clearly differentially distributed in neurons ...
Daniela Peters, Jana Berger, Kristina Langnaese, Christian Derst, Vince I Madai, Michael Krauss, Klaus-Dieter Fischer, Rüdiger W Veh, Gregor Laube   +8 more
doaj   +2 more sources

Screening of Saccharomyces and Non-Saccharomyces Wine Yeasts for Their Decarboxylase Activity of Amino Acids

Foods, 2022
The type and quantity of precursor amino acids present in grape must that are used by wine yeasts affect the organoleptic and health properties of wine. The aim of this work was to conduct a preliminary screening among Saccharomyces and non-Saccharomyces
Gabriella Siesto, Maria Rosaria Corbo, Rocchina Pietrafesa, Milena Sinigaglia, Patrizia Romano, Antonio Bevilacqua   +5 more
doaj   +1 more source

Arginine- and Polyamine-Induced Lactic Acid Resistance in Neisseria gonorrhoeae. [PDF]

PLoS ONE, 2016
Microbe-derived lactic acid protects women from pathogens in their genital tract. The purpose of this study was to determine lactic acid susceptibility of Neisseria gonorrhoeae, and identify potential acid resistance mechanisms present in this pathogen ...
Zheng Gong, M Matt Tang, Xueliang Wu, Nancy Phillips, Dariusz Galkowski, Gary A Jarvis, Huizhou Fan   +6 more
doaj   +1 more source

Uric Acid Deteriorates Load-Free Cell Shortening of Cultured Adult Rat Ventricular Cardiomyocytes via Stimulation of Arginine Turnover

Biology, 2022
Hyperuricemia is a risk factor for heart disease. Cardiomyocytes produce uric acid via xanthine oxidase. The enzymatic reaction leads to oxidative stress in uric-acid-producing cells.
Martin Weber, Rolf Schreckenberg, Klaus-Dieter Schlüter   +2 more
doaj   +1 more source

A molecular mechanism for eflornithine resistance in African trypanosomes [PDF]

, 2010
Human African trypanosomiasis, endemic to sub-Saharan Africa, is invariably fatal if untreated. Its causative agent is the protozoan parasite Trypanosoma brucei.
Creek Darren, Watson David G., Burchmore, Richard J S, Barrett, M.P., Michael P. Barrett, Woods, DJ, Pui Ee Wong, Vincent, I.M., Darren Creek, Vincent, IM, Kamleh, M.A., Richard J S Burchmore, Wong, P.E., Kamleh, Mohammed A, Woods, Debra J, Creek, Darren, Richard J. S. Burchmore, Wong, PE, Vincent, Isabel M, Isabel M Vincent, Michael P Barrett, Isabel M. Vincent, Kamleh, MA, Watson, DG, Woods, D.J., Wong, Pui Ee, Woods Debra J., Mohammed A. Kamleh, David G. Watson, Barrett, Michael P, Creek, D., Barrett Michael P., Barrett, MP, Burchmore, R.J.S., Wong Pui Ee, David G Watson, Kamleh Mohammed A., Vincent Isabel M., Watson, David G, Burchmore, RJS, Creek, D, Watson, D.G., Debra J Woods, Debra J. Woods, Mohammed A Kamleh, Burchmore Richard J. S.   +45 more
core   +5 more sources

mRNA dynamics and alternative conformations adopted under low and high arginine concentrations control polyamine biosynthesis in Salmonella. [PDF]

PLoS Genetics, 2019
Putrescine belongs to the large group of polyamines, an essential class of metabolites that exists throughout all kingdoms of life. The Salmonella speF gene encodes an inducible ornithine decarboxylase that produces putrescine from ornithine.
Tamar Ben-Zvi, Alina Pushkarev, Hemda Seri, Maya Elgrably-Weiss, Kai Papenfort, Shoshy Altuvia   +5 more
doaj   +1 more source

Inhibition or promotion, the potential role of arginine metabolism in immunotherapy for colorectal cancer

All Life, 2023
Colorectal cancer (CRC) is the third most common cancer in the world, with increasing morbidity and mortality. The current diagnosis and treatment plan rely on early detection and comprehensive treatment based on surgery.
Chengyang Chen, Xia Jiang, Zengren Zhao
doaj   +1 more source

The Neighboring Subunit Is Engaged to Stabilize the Substrate in the Active Site of Plant Arginases

Frontiers in Plant Science, 2020
Arginine acts as a precursor of polyamines in plants in two known pathways, agmatine and ornithine routes. It is decarboxylated to agmatine by arginine decarboxylase, and then transformed to putrescine by the consecutive action of agmatine iminohydrolase
Bartosz Sekula
doaj   +1 more source

Serum levels of polyamine synthesis enzymes increase in diabetic patients with breast cancer

Endocrine Connections, 2017
In this study, it was aimed to investigate the relationship between diabetes and breast cancer and the detection of enzymes and ornithine levels in polyamine synthesis pathway in diabetes, breast cancer and diabetic breast cancer patients.
V Kenan Çelik, Sercan Kapancık,, Turgut Kaçan, Selen Baloglu Kaçan, Serkan Kapancık, Hasan Kılıçgün   +5 more
doaj   +1 more source