Structure and mechanism of acetolactate decarboxylase [PDF]
, 2013 Acetolactate decarboxylase catalyzes the conversion of both enantiomers of acetolactate to the (R)-enantiomer of acetoin, via a mechanism that has been shown to involve a prior rearrangement of the non-natural (R)-enantiomer substrate to the natural (S ...
Victoria A. Marlow +9 more
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Arginine Metabolism and Its Potential in Treatment of Colorectal Cancer
Frontiers in Cell and Developmental Biology, 2021 Colorectal cancer is the leading cause of death from cancer globally. The current treatment protocol still heavily relies on early detection and surgery.
Tao Du, Junyi Han
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Screening and Production of Fungal Arginine Degrading Enzymes and Testing Their Effects in Auxotrophic Cancers [PDF]
International Journal of Medical ArtsThe aim of the work: Finding and evaluating fungal arginine-degrading enzymes from various Egyptian soil habitats as anticancer mediators against auxotrophic cancer cells was the goal.
Mohammed Kassab
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L-arginine deprivation impairs Leishmania major-specific T-cell responses. [PDF]
, 2009 The amino acid L-arginine plays a crucial role in the regulation of immune responses. We have recently shown that uncontrolled replication of Leishmania parasites at the site of pathology correlates with high levels of arginase activity in nonhealing ...
Markus Munder +7 more
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Development of a Pseudomonas aeruginosa Agmatine Biosensor
Biosensors, 2014 Agmatine, decarboxylated arginine, is an important intermediary in polyamine production for many prokaryotes, but serves higher functions in eukaryotes such as nitric oxide inhibition and roles in neurotransmission.
Adam Gilbertsen, Bryan Williams
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Plasma arginine vasopressin concentrations in epileptics under monotherapy [PDF]
, 1983 Plasma arginine vasopressin concentrations were determined by radio-immunoassay in 112 adult epileptics who were taking carbamazepine, phenytoin, primidone, or sodium valproate in long-term monotherapy, and in 19 controls.
Rascher, W. +5 more
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Partial cloning and characterization of an arginine decarboxylase in the kidney [PDF]
, 1995 Partial cloning and characterization of an arginine decarboxylase in the kidney. Using homology-based polymerase chain reaction (PCR) amplification, we demonstrate the presence of arginine decarboxylase mRNA in tissues involved in arginine metabolism ...
Klahr, Saulo +3 more
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Differential impact of L-arginine deprivation on the activation and effector functions of T cells and macrophages. [PDF]
, 2008 The metabolism of the amino acid L-arginine is emerging as a crucial mechanism for the regulation of immune responses. Here, we characterized the impact of L-arginine deprivation on T cell and macrophage (MPhi) effector functions: We show that whereas L ...
Corset, C +20 more
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Cysteine Thioaldehydes: Photolytic Generation, Reactivity, and Biological Implications
Angewandte Chemie, EarlyView.Photolysis of cysteine phenacylsulfides bearing non‐conjugating electron‐withdrawing substituents leads to high conversions into cysteine thioaldehydes through a Norrish type‐II pathway. This methodology enabled the study of the aqueous reactivity of these important biosynthetic intermediates, which, depending on peptide sequence, pH and buffer ...
Ardra Karthika +9 more
wiley +2 more sources
Pyruvoyl dependent arginine decarboxylases from Chlamydiae and Crenarchaea [PDF]
, 2008 textArginine decarboxylase is a key enzyme involved in the polyamine pathway of organisms. Pyruvoyl-dependent arginine decarboxylases are expressed in the form of proenzymes that self-cleave to form N-terminal [beta] and C-terminal [alpha] subunits ...
Giles, Teresa Neelima
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