Results 131 to 140 of about 12,122 (173)

Time and Media-Dependent Modulation of Sperm Capacitation in Red-Rumped Agouti (Dasyprocta leporina Linnaeus, 1758). [PDF]

open access: yesMol Reprod Dev
de Oliveira LRM   +9 more
europepmc   +1 more source

Agouti-related protein in the hypothalamic paraventricular nucleus: effect on feeding

Peptides, 2000
Agouti-related protein (Agrp) is an endogenous melanocortin-4 receptor antagonist implicated in the regulation of food intake. Effects of Agrp on feeding under varying conditions were investigated. Agrp (10 to 100 pmol) was injected into the hypothalamic paraventricular nucleus of satiated (a.m. and p.m.
Michelle Wirth
exaly   +3 more sources

Peptoid mimics of agouti related protein

Bioorganic & Medicinal Chemistry Letters, 2003
The Agouti Related Protein (AGRP) is an endogenous antagonist of melanocortin-3 and -4 receptors, each of which plays a key role in body weight homeostasis. We designed a peptoid trimer based on AGRP 111-113 in which a single chiral atom is used to partially restrain the backbone structure. Peptoid 5 displaced both radiolabeled Nle4-alpha-MSH (IC(50)=3.
Darren A, Thompson   +6 more
openaire   +2 more sources

Agouti‐Related Protein: Appetite or Reward?

Annals of the New York Academy of Sciences, 2003
Abstract:Agouti‐related protein (AgRP) is an orexigenic peptide that acts as an antagonist of the melanocortin‐3 and ‐4 receptors in the hypothalamus. Studies suggest that the melanocortin and opioid systems interact in the control of ingestive behavior. Also, AgRP has been shown to especially increase intake of a palatable diet.
Pawel K, Olszewski   +4 more
openaire   +2 more sources

Role of Agouti-related protein in adrenal steroidogenesis

Molecular and Cellular Endocrinology, 2007
The levels of Agouti-related protein (AgRP) mRNA in the adrenal are second only to those in the hypothalamus, raising questions regarding its target binding sites and its specific role in adrenal steroidogenesis. We and others demonstrated the presence of a population of melanocortin receptor-4 (MC4R) positively coupled to steroidogenesis in adrenal ...
Mabrouka, Doghman   +4 more
openaire   +2 more sources

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