Strategies for AIDS vaccines [PDF]
Journal of Antimicrobial Chemotherapy, 1996 In the global AIDS epidemic, over half of all infections have occurred in people less than 25 years old resulting in profound social, economic and demographic consequences. Current estimates indicate that the present 15 million HIV infections will increase to over 30 million by the end of the millennium.
E J, Stott, G C, Schild
openaire +2 more sources
Immunogens and Antigen Processing: Report from a Global HIV Vaccine Enterprise Working Group [PDF]
, 2010 The Global HIV Vaccine Enterprise convened a meeting of a Working Group in July 2009 to discuss recent progress in rational design of the components of an HIV vaccine, such as inserts, vectors and adjuvants,and in understanding antigen processing and ...
John Mascola +3 more
core +3 more sources
Factors Associated with Immunization Opinion Leadership among Men Who Have Sex with Men in Los Angeles, California [PDF]
, 2018 We sought to identify the characteristics of men who have sex with men (MSM) who are opinion leaders on immunization issues and to identify potential opportunities to leverage their influence for vaccine promotion within MSM communities.
Bednarczyk, Robert +9 more
core +3 more sources
Functional comparison of SARS-CoV-2 with closely related pangolin and bat coronaviruses
Cell Discovery, 2021 The origin and intermediate host for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is yet to be determined. Coronaviruses found to be closely related to SARS-CoV-2 include RaTG13 derived from bat and two clusters (PCoV-GD and PCoV-GX) of ...
Jianhui Nie +23 more
doaj +1 more source
Clofazimine: A Promising Inhibitor of Rabies Virus
Frontiers in Pharmacology, 2021 With an almost 100% mortality rate, rabies virus (RABV) infection is a global concern. Limited post-exposure prophylaxis and lack of an effective treatment necessitate novel antiviral therapies against RABV.
Jiajing Wu +16 more
doaj +1 more source
The comparative value of feline virology research: can findings from the feline lentiviral vaccine be translated to humans? [PDF]
, 2017 Feline immunodeficiency virus (FIV) is a lentivirus of domestic cats that shares several similarities with its human counterpart, human immunodeficiency virus (HIV).
Beczkowski, Paweł M. +5 more
core +1 more source
Vaccine innovation, translational research and the management of knowledge accumulation [PDF]
, 2012 What does it take to translate research into socially beneficial technologies like vaccines? Current policy that focuses on expanding research or strengthening incentives overlooks how the supply and demand of innovation is mediated by problem-solving ...
Andre +86 more
core +2 more sources
Preclinical Assessment of HIV Vaccines and Microbicides by Repeated Low-Dose Virus Challenges [PDF]
, 2005 BACKGROUND: Trials in macaque models play an essential role in the evaluation of biomedical interventions that aim to prevent HIV infection, such as vaccines, microbicides, and systemic chemoprophylaxis.
Feinberg, Mark B +3 more
core +5 more sources
Analysis of the evolution, infectivity and antigenicity of circulating rabies virus strains
Emerging Microbes and Infections, 2022 Rabies virus has existed for thousands of years and is circulating in many species. In the present study, a total of 2896 rabies viruses isolated worldwide were phylogenetically classified into ten clusters based on the G gene sequence, and these ...
Meina Cai +12 more
doaj +1 more source
Envelope Determinants of Equine Lentiviral Vaccine Protection [PDF]
, 2013 Lentiviral envelope (Env) antigenic variation and associated immune evasion present major obstacles to vaccine development. The concept that Env is a critical determinant for vaccine efficacy is well accepted, however defined correlates of protection ...
A Kumar +76 more
core +3 more sources