Results 21 to 30 of about 123,499 (307)

Medicines and vaccines for the world's poorest: Is there any prospect for public-private cooperation? [PDF]

open access: yes, 2005
This paper reviews the current status of the global pharmaceutical industry and its research and development focus in the context of the health care needs of the developing world.
Pathania, Vikram, Scheffler, Richard M
core   +3 more sources

Roadblocks to translational challenges on viral pathogenesis. [PDF]

open access: yes, 2013
Distinct roadblocks prevent translating basic findings in viral pathogenesis into therapies and implementing potential solutions in the clinic. An ongoing partnership between the Volkswagen Foundation and Nature Medicine resulted in an interactive ...
Deeks, Steven   +4 more
core   +1 more source

Child privacy rights: A ‘Cinderella’ issue in HIV-prevention research

open access: yesSouthern African Journal of HIV Medicine, 2013
Legal debates regarding child participation in HIV research have tended to focus on issues of informed consent. However, much less attention has been given to privacy; accordingly, we classify this as a ‘Cinderella issue’ that has been excluded from ‘the
Ann Elaine Strode, Catherine Slack
doaj   +1 more source

Biochemical prevention and treatment of viral infections – A new paradigm in medicine for infectious diseases [PDF]

open access: yes, 2004
For two centuries, vaccination has been the dominating approach to develop prophylaxis against viral infections through immunological prevention. However, vaccines are not always possible to make, are ineffective for many viral infections, and also carry
Fang, Fang, Le Calvez, Hervé, Yu, Mang
core   +3 more sources

Sex, lies and disclosures: Researchers and the reporting of under-age sex

open access: yesSouthern African Journal of HIV Medicine, 2009
Children are a vulnerable group and require legal protection due to their youth and inexperience. Resultantly, various provisions in the law ensure the care and protection of children through mechanisms such as the mandatory reporting of abuse.
Ann Strode, Catherine Slack
doaj   +1 more source

Antibody-dependent cellular cytotoxicity response to SARS-CoV-2 in COVID-19 patients

open access: yesSignal Transduction and Targeted Therapy, 2021
Antibody-dependent cellular cytotoxicity (ADCC) responses to viral infection are a form of antibody regulated immune responses mediated through the Fc fragment. Whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) triggered ADCC responses
Yuanling Yu   +25 more
doaj   +1 more source

Promotion of access to essential medicines for Non-Communicable Diseases: Practical implications of the UN Political Declaration [PDF]

open access: yes, 2013
Access to medicines and vaccines to prevent and treat non-communicable diseases (NCDs) is unacceptably low worldwide. In the 2011 UN political declaration on the prevention and control of NCDs, heads of government made several commitments related to ...
Abdraimova   +60 more
core   +3 more sources

Development of a neutralization assay and bioluminescent imaging mouse model for Dehong virus (DEHV) using a pseudovirus system

open access: yesMicrobiology Spectrum
Dehong virus (DEHV) is an emerging filamentous virus of considerable interest. However, research involving DEHV remains limited, and no suitable models exist to investigate its pathogenicity or transmission.
Xuelian Wu   +13 more
doaj   +1 more source

Health in the sustainable development goals: ready for a paradigm shift? [PDF]

open access: yes, 2015
The Millennium Development Goals (MDGs) galvanized attention, resources and accountability on a small number of health concerns of low- and middle-income countries with unprecedented results.
Buse, K, Hawkes, S
core   +1 more source

Ten emerging SARS-CoV-2 spike variants exhibit variable infectivity, animal tropism, and antibody neutralization

open access: yesCommunications Biology, 2021
Li Zhang, Zhimin Cui, and Qianqian Li et al. compare the infectivity, host tropism, and antigenicity of 10 SARS-CoV-2 variants using a VSV-based pseudovirus system. Their results suggest that variants carrying E484K display the most significant reduction
Li Zhang   +16 more
doaj   +1 more source

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