Results 91 to 100 of about 375,726 (199)

Poly(I:C)‐Activated Nasal Fibroblasts Promote Eosinophil Recruitment in CRSwNP

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by persistent mucosal inflammation and eosinophilic infiltration. Although epithelial and immune cells have been widely studied, the role of nasal fibroblasts in innate immune activation and eosinophil recruitment remains unclear.
Chaewon Shin, An‐Gi Kim, Byeong Min Yu, Woo‐Keun Kwon, Min‐Ho Hwang, Joo‐Hoo Park   +5 more
wiley   +1 more source

Olfactory Function in Cystic Fibrosis: Outcome Measures, Olfactory Dysfunction Prevalence and the Impact of Management—A Systematic Review and Meta‐Analysis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Olfactory dysfunction (OD) is an increasingly recognized but under‐investigated comorbidity of cystic fibrosis (CF). Its prevalence, assessment methods, and response to CF‐directed treatment, including highly effective modulator therapy (HEMT) remains incompletely characterized.
Luca Cox, Kofi Cox, Katherine Whitcroft, Susanne Weise, Sonal Kansra, Eishaan Bhargava   +5 more
wiley   +1 more source

Airway epithelial cells and asthma: from barrier disruption to alarmin-driven inflammation and remodeling

Cell Division
Asthma is a highly heterogeneous chronic inflammatory airway disease whose pathophysiology is determined by a combination of genetic, environmental, and immune factors.
Xiwen Xu, Bowen Zhang
doaj   +1 more source

Assessing the Mucosal Inflammatory Endotype of Obesity in Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) is a heterogeneous inflammatory syndrome of the paranasal sinuses that is defined phenotypically as either with nasal polyps (CRSwNP) or without nasal polyps (CRSsNP). More recently, inflammatory markers have been used to cluster patients into putative endotypes that are presumed to have a common ...
Jeffanie W. Gayoso, Li‐Ching Huang, Quanhu Sheng, Daniel Lofgren, Ping Li, Katherine Cahill, Mason Krysinski, Rakesh K. Chandra, Justin H. Turner, Naweed Chowdhury   +9 more
wiley   +1 more source

{alpha}7 nicotinic acetylcholine receptor regulates airway epithelium differentiation by controlling basal cell proliferation.

, 2009
International audienceAirway epithelial basal cells are known to be critical for regenerating injured epithelium and maintaining tissue homeostasis.
Polette, Myriam, C., Birembaut, Philippe, L., Cloëz-Tayarani, Isabelle, Christine Terryn, Jean-Marie Tournier, Maouche, Kamel, Zahm, Jean-Marie, Terryn, Christine, Jean-Pierre Changeux, Jean-Marie Zahm, Changeux, Jean-Pierre, Kamel Maouche, Coraux, Christelle, Isabelle Cloëz-Tayarani, Burlet, Henriette, Medjber, Kahina, Henriette Burlet, Thomas Jolly, Tournier, Jean-Marie, Christelle Coraux, Jolly, Thomas, Myriam Polette, Kahina Medjber, Philippe Birembaut   +23 more
core   +1 more source

Airway Epithelial Dysfunction in Asthma: Relevant to Epidermal Growth Factor Receptors and Airway Epithelial Cells

, 2020
Airway epithelium plays an important role as the first barrier from external pathogens, including bacteria, viruses, chemical substances, and allergic components.
Kaho Akimoto, Hideki Inoue, Akihiko Tanaka, Tetsuya Homma, Hironori Sagara   +4 more
core   +1 more source

Innervation of the tubarial glands: A hypothesis‐driven anatomical review

The Anatomical Record, EarlyView.
Abstract The tubarial glands have been described as a macroscopic bilateral glandular complex in the posterolateral nasopharynx near the torus tubarius and the pharyngeal opening of the Eustachian tube. Since their recognition on prostate‐specific membrane antigen‐based imaging, their anatomical classification has remained debated, with converging ...
Mugurel Constantin Rusu, Ivan Varga, Răzvan Costin Tudose   +2 more
wiley   +1 more source

[Regeneration of injured airway epithelium]

, 2006
The airway surface epithelium is frequently injured by microorganisms and viruses due to its permanent contact with the external medium. Following injury, the epithelium is able to repair itself and regenerate through several mechanisms including ...
Coraux, Christelle, Le Simple, Pierre, Puchelle, Edith, Hajj, Rodolphe   +3 more
core   +3 more sources

Computational fluid dynamics simulations of airflow through the nasal passages of rhinolophoid bats

The Anatomical Record, EarlyView.
Abstract The nasal passages of bats that emit their echolocation call through their nostrils have adapted for sound emission as well as standard respiratory and olfactory functions. Rhinolophids, hipposiderids and rhinonycterids all use a high duty cycle (HDC) echolocation strategy.
Carley Goodwin, Jason M. Bourke, Daisuke Koyabu, Kyle N. Armstrong, Vuong T. Tu, Thongchai Ngamprasertwong, Thanakul Wannaprasert, Laura A. B. Wilson   +7 more
wiley   +1 more source

Paranasal recesses and rostral airspace volume covary with echolocation call frequency in emballonurid bats

The Anatomical Record, EarlyView.
Abstract The mammalian rostrum has multiple functions including serving as the upper jaw, supporting olfactory sensory structures, conditioning inspired air, and—for some mammals—transmitting sound. Several groups of bats independently evolved bony inflations on the dorsolateral surfaces of their rostra.
Abigail A. Curtis, Nancy B. Simmons, Timothy D. Smith, Thomas P. Eiting, Sharlene E. Santana   +4 more
wiley   +1 more source