Results 71 to 80 of about 375,726 (199)

Airway epithelium in lung transplantation: a potential actor for post-transplant complications?

European Respiratory Review
Lung transplantation, a critical intervention for end-stage lung diseases, is frequently challenged by post-transplant complications. Indeed, primary graft dysfunction, anastomotic complications, infections and acute and chronic rejections pose ...
Jules Milesi, Delphine Gras, Pascal Chanez, Benjamin Coiffard   +3 more
doaj   +1 more source

Plasticity in the airway epithelium

, 1990
Normal cell turnover as well as the response to injury require cell proliferation and differentiation. The airway epithelium maintains these processes throughout adult life.
B. Jany, C. Basbaum
core   +1 more source

A Robust Bio‐Supportive Hydrogel Patch for Full‐Thickness Repair of Gastroesophageal Defects

Advanced Science, EarlyView.
Gastroesophageal defect repair remains a formidable clinical challenge plagued by high leakage and life‐threatening complications. We develop a double‐disc, highly crystalline PVA‐based RBS hydrogel patch featuring suture‐free sealing, robust acid/enzyme resistance and mechanical durability.
Xingqi Song, Zhewei Shuai, Weiyan Sun, Liang Chen, Yiwei Shen, Jiateng Hu, Yuanqi Ma, Jie Luo, Meilin Huang, Yan Luo, Yunlang She, Guangdong Zhou, Chang Chen, Dong Lei   +13 more
wiley   +1 more source

How early life respiratory viral infections impact airway epithelial development and may lead to asthma

Frontiers in Pediatrics
Childhood asthma is a common chronic disease of the airways that results from host and environment interactions. Most risk factor studies of asthma point to the first year of life as a susceptibility window of mucosal exposure that directly impacts the ...
Sergejs Berdnikovs, Dawn C. Newcomb, Tina V. Hartert, Tina V. Hartert   +3 more
doaj   +1 more source

Innate immune responses of the airway epithelium.

, 2010
Barrier epithelia, especially airway epithelial cells, are persistently exposed to micro-organisms and environmental factors. To protect the host from these microbial challenges, many immune strategies have evolved.
윤주헌, 김창훈, 유지환
core   +1 more source

Curvature‐Directed Elongation and Chiral Tilting Drive Asymmetric Tissue Patterning

Advanced Science, EarlyView.
Curvature and cell handedness together break tissue symmetry. On convex and concave surfaces, cells elongate along opposite geometric axes and tilt in a consistent chirality‐driven direction, yielding opposite alignment patterns from the same cells. Reversing intrinsic cell chirality reverses both.
Liyao Xu, Frank Daniel Peters, Haokang Zhang, Madison Stiefbold, Thangam Ramar, Aditya Agarwal, Leo Q. Wan   +6 more
wiley   +1 more source

Regeneration of a well-differentiated human airway surface epithelium by spheroid and lentivirus vector-transduced airway cells.

, 2004
BACKGROUND: Following injury to the airway epithelium, rapid regeneration of a functional epithelium is necessary in order to restore the epithelial barrier integrity.
Coraux, Christelle, Castillon, Nicolas, Delenda, Christophe, Avril-Delplanque, Aurélie, Danos, Olivier, Puchelle, Edith, Péault, Bruno   +6 more
core   +1 more source

ACAT1‐Mediated SP1‐K694 Lactylation Promotes M1 Macrophage Polarization via TREM1 Transcription in COPD

Advanced Science, EarlyView.
Upon cigarette smoke exposure(CSE), LDHA expression is increased in lung macrophages, promoting the conversion of pyruvate to lactate and elevating the lactylation level of SP1 at the K694 site. This, in turn, enhances SP1 enrichment at the TREM1 promoter, increases TREM1 expression, promoted M1 macrophage polarization, and triggers the secretion of ...
Ling Lin, Ping Zhang, Qing Song, Tao Li, Yuqin Zeng, Ping Chen   +5 more
wiley   +1 more source

A translational view of airway epithelial dysfunction in COPD

European Respiratory Review
COPD is a heterogeneous, progressive inflammatory airway disease, with patients presenting with a wide variety of symptoms, comorbid conditions and underlying pathophysiology.
Christopher E. Brightling, Mona Bafadhel, MeiLan K. Han, Jean-Francois Papon, Klaus F. Rabe, Paola Rogliani, Dave Singh   +6 more
doaj   +1 more source

Role of Homeobox A1 in Airway Epithelial Generation from Human Airway Basal Cells

Cells
Airway basal cells from chronic obstructive pulmonary disease patients show a reduction in HOXA1 expression and generate an abnormal airway epithelium.
Mohsen Tabasi, Nathaniel Chen, Umadevi Sajjan   +2 more
doaj   +1 more source