Results 111 to 120 of about 62,023 (261)

Biomarkers of lung congestion and injury in acute heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 781-789, April 2025.
Abstract Acute heart failure (AHF) classification and management are primarily based on lung congestion and/or hypoperfusion. The quantification of the vascular and tissue lung damage is not standard practice though biomarkers of lung injury may play a relevant role in this context.
Marco Guazzi, Gabriele Novello, Francesca Bursi, Anna Caretti, Noemi Furlotti, Ross Arena, Paola Argiento, Julio Núñez, Antoni Bayes‐Genis, Marco Metra   +9 more
wiley   +1 more source

Tracheal wash culture is not associated with bronchial infection, remodelling or inflammation in horses with asthma

Equine Veterinary Journal, EarlyView.
Abstract Background Antimicrobials are commonly prescribed for the treatment of equine asthma, despite limited evidence supporting their use. Tracheal wash (TW) bacterial culture results are known to influence antimicrobial prescription decisions. Objectives To determine whether a positive TW bacterial culture in horses with asthma is associated with ...
Laurence Leduc, Guillaume St‐Jean, Jean‐Pierre Lavoie   +2 more
wiley   +1 more source

Resveratrol Ameliorates Allergic Rhinitis by Activating SIRT1 to Disrupt the Mitochondrial ROS‐Inflammation Vicious Cycle

Flavour and Fragrance Journal, EarlyView.
This study demonstrates that resveratrol alleviates allergic rhinitis by activating SIRT1, thereby disrupting the mitochondrial ROS‐inflammatory cycle, improving mitochondrial function, promoting anti‐inflammatory M2 macrophage polarisation, and reducing epithelial oxidative damage.
Xinyu Zhou, Yi Yue, Wenwen Qi, Wenqing Zhu, Xinran Liu, Rongcui Sui, Xuanchen Zhou   +6 more
wiley   +1 more source

Syncing Health Timing: Exploring the Interplay of Circadian Rhythms, Obesity, and Cardiovascular Diseases

Food Safety and Health, EarlyView.
Circadian rhythm disruption impairs metabolic regulation, appetite control, and vascular function, promoting obesity and cardiovascular diseases. Evidence highlights a bidirectional relationship where metabolic disorders further disturb circadian timing.
Ghizal Fatima, István Dalmadi, Anna Jánosi, Krisztina Takács, Eszter Halmy   +4 more
wiley   +1 more source

Cigarette Smoke Exposure Attenuates T2R‐Mediated Apoptosis in Head and Neck Squamous Cell Carcinoma

Head &Neck, EarlyView.
ABSTRACT Background Tobacco use is associated with worse outcomes in head and neck squamous cell carcinoma (HNSCC). Bitter taste receptor (T2R) activation induces apoptosis via calcium‐dependent signaling, and higher T2R expression correlates with increased survival in HNSCC.
Kyle Polen, Sarah Sywanycz, Gavin Turner, Brianna L. Hill, Lily Huang, Zoey A. Miller, Casey Hanna, Lovely Raghav, Devraj Basu, Robert J. Lee, Ryan M. Carey   +10 more
wiley   +1 more source

Zinc deficiency as a codeterminant for airway epithelial barrier dysfunction in an ex vivo model of COPD

International Journal of COPD, 2017
Eugene Roscioli,1,2 Hubertus PA Jersmann,1,2 Susan Lester,2,3 Arash Badiei,1,2 Andrew Fon,1,2 Peter Zalewski,2,4 Sandra Hodge1,2 1Department of Thoracic Medicine, Royal Adelaide Hospital, 2Department of Medicine, The University of Adelaide, Adelaide ...
Roscioli E, Jersmann HPA, Lester S, Badiei A, Fon A, Zalewski P, Hodge S   +6 more
doaj  

Gene signatures characterizing driver mutations in lung squamous carcinoma are predictive of the progression of pre‐cancer lesions

International Journal of Cancer, EarlyView.
What's New? Lung squamous cell carcinoma (LUSC) is more aggressive than lung adenocarcinoma, and is most often diagnosed at an advanced stage. Here, the authors evaluated gene expression data from LUSC tumors and came up with gene signatures for 34 genetic abnormalities whose expression changes throughout different precancerous stages. Several of these
Yupei Lin, Venugopalareddy Mekala, Jianrong Li, Xiang Wang, Muhammad Aminu, Jia Wu, Jianjun Zhang, Robert Taylor Ripley, Christopher I. Amos, Chao Cheng   +9 more
wiley   +1 more source

Airway epithelium and asthma

, 2020
Asthma is a respiratory chronic inflammatory disease with well-established symptoms, but the pathophysiological mechanisms remain largely unexplored. In this thesis, we aim to analyse and clarify responses of asthmatic airway epithelial cells.In chapter 2, we showed that bronchial epithelium from mild asthma patients in response to in vivo RV16 ...
openaire   +2 more sources

Maternal and infant gut microbiome

iMeta, EarlyView.
The maternal–infant continuum involves critical windows of host–microbiota co‐adaptation. Preconception, maternal and paternal microbiomes modulate immunity and reproduction. During pregnancy, a gut–placenta axis emerges, where microbial metabolites influence fetal growth or contribute to complications like gestational diabetes mellitus (GDM ...
Huidi Wang, Felicia Tin, Hui Chen, Fuxin Jiao, Min Wu, Shanshan Sun, Lisha Lin, Die Li, Huimin Zheng, Zhenxin Niu, Mengyao Lan, Bahtiyar Yilmaz, Johan G. Eriksson, Mengjia Wang, Andrew Macpherson, Jose C. Clemente, Jia Xu, Ri‐hua Xie, Xiaojiao Zheng, Tao Zhou, Jinfeng Wang, Wei Shen, Bing Huang, Xia Chen, Hai Li, Yan He   +25 more
wiley   +1 more source

Exposure to micro‐ and nano‐plastics: From human internal burden to systems‐level health‐risk interpretation

iMeta, EarlyView.
Micro‐ and nano‐plastics (MNPs) can enter the human body through inhalation, ingestion, contact with consumer products, and iatrogenic routes. The clinical relevance of MNP exposure should be interpreted at three levels: barrier interaction, cellular stress, and system‐level disruption, with key mechanisms including oxidative stress, mitochondrial ...
Chen Tu, Jie Yang, Jingyi Liao, Rongkui Hu, Yudong Feng, Di Wu, Yankai Xia, Dan Wang, Jinrong Tang, Xianzheng Yuan, Dong Zhu, Jing Wei, Li Xu, Mingkai Xu, Xuetao Guo, Jian Zhao, Qiqing Chen, Zhenming Zhang, Lianzhen Li, Yini Ma, Xiaoxu Jiang, Kai Zhang, Cheng Peng, Mengyao Li, Ning Shen, Willie J. G. M. Peijnenburg, Matthias C. Rillig, Jason C. White, Yongming Luo, Ningwei Zhao   +29 more
wiley   +1 more source