Results 131 to 140 of about 375,726 (199)

Air Pollution Quinones Impair Intestinal Barrier Integrity and Endoplasmic Reticulum in Differentiated Caco‐2 Cells

Journal of Applied Toxicology, EarlyView.
ABSTRACT Particulate matter (PM) is a major global health threat, linked to millions of deaths annually. Beyond inhalation, PM components reach the gastrointestinal tract through the mucociliary escalator or contaminated food and water. Among PM's organic fraction, redox‐active quinones such as 1,2‐naphthoquinone (NQ) and 9,10‐phenanthrenequinone (PQ ...
Franco Cervellati, Giulia Trinchera, Alice Casoni, Alessandra Pecorelli, Mascia Benedusi, Maria Chiara Pietrogrande, Giuseppe Valacchi   +6 more
wiley   +1 more source

High‐Content Screening Comparison of 1R6F Cigarette Smoke Extract and Selected Heated Tobacco and Electronic Vapour Product Aerosol Extracts in Endothelial and Bronchial Epithelial Cell Models

Journal of Applied Toxicology, EarlyView.
ABSTRACT Cigarettes induce oxidative stress and DNA damage, processes that contribute to cardiovascular and pulmonary disease. High content screening (HCS) is an increasingly valuable tool for comparative toxicology because it enables simultaneous quantification of multiple mechanistic endpoints at single‐cell resolution. In this study, HCS was used to
Edgar Trelles Sticken, Konstantinos Papikinos, Fiona Chapman, Roman Wieczorek, Sarah Jean Pour, Torge Evenburg, Sandra Otte, Tiandan Wu, Liam Simms, Matthew Stevenson   +9 more
wiley   +1 more source

Zinc deficiency as a codeterminant for airway epithelial barrier dysfunction in an ex vivo model of COPD

International Journal of COPD, 2017
Eugene Roscioli,1,2 Hubertus PA Jersmann,1,2 Susan Lester,2,3 Arash Badiei,1,2 Andrew Fon,1,2 Peter Zalewski,2,4 Sandra Hodge1,2 1Department of Thoracic Medicine, Royal Adelaide Hospital, 2Department of Medicine, The University of Adelaide, Adelaide ...
Roscioli E, Jersmann HPA, Lester S, Badiei A, Fon A, Zalewski P, Hodge S   +6 more
doaj  

Ultrasonic Image Characteristics of Palatine Tonsils in Healthy Children and Analysis of Factors Influencing Image Quality

Journal of Clinical Ultrasound, Volume 53, Issue 3, Page 436-444, March/April 2025.
The ultrasound detection rate of the palatine tonsils in children was good. There are characteristic ultrasonic image manifestations. Tonsil ultrasound image quality is affected by individual and local factors. ABSTRACT Objective To explore the ultrasonic image characteristics of palatine tonsils in healthy children and the factors affecting image ...
Ying Cao, Lei Sun, XiaoPeng Li, Qi Zhang, Yue Gao, Hua Wang   +5 more
wiley   +1 more source

Trans‐Cervical Ultrasound Imaging of the Adult Palatine Tonsils

Journal of Medical Radiation Sciences, EarlyView.
Ultrasound imaging of the adult palatine tonsils using a trans‐cervical approach can be used to assess the tonsillar region for intratonsillar and peritonsillar abscesses. An understanding of the sonographic anatomy, technique and tonsillar pathology is required to perform and interpret imaging and inform patient management.
Michelle Fenech, Tristan Reddan
wiley   +1 more source

A preterm neonate with infantile liver failure syndrome 1 due to leucyl‐tRNA synthetase 1 gene (LARS1) mutations with a histopathologic phenotype of neonatal hemochromatosis

JPGN Reports, EarlyView.
Abstract We report a case of a premature, growth‐restricted female infant with feeding intolerance and coagulopathy, treated initially for sepsis, who progressed to neonatal acute liver failure and end‐stage hepatic encephalopathy after a prolonged hospitalization with extensive diagnostic evaluation, and was found by autopsy to have histopathologic ...
Adrienne Bruder, Naomi Laventhal, Raja Rabah, Jacqueline Meadow   +3 more
wiley   +1 more source

Clinical and Demographic Predictors of In‐Hospital Mortality in Adult SJS/TEN Hospitalizations: A National Inpatient Sample Analysis 2017–2022

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Stevens−Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe mucocutaneous reactions associated with significant morbidity and mortality. Published studies have identified a limited number of variables predictive of death, but their description of acute complications is sparse.
Damilola Oladinni, Neil Manadan, Ehizogie Edigin   +2 more
wiley   +1 more source

Mechanism of RNA‐Binding Protein ELAVL1 in Promoting Th2 Cell Differentiation Through Stabilizing CPA3 mRNA in Allergic Rhinitis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study aimed to elucidate the role of the RNA‐binding protein embryonic lethality abnormal vision‐like protein 1 (ELAVL1) in the pathogenesis of allergic rhinitis (AR), specifically by investigating its potential to promote T helper 2 (Th2) cell differentiation by regulating the stability of carboxypeptidase A3 (CPA3) mRNA.
Meng‐Ya Liu, Hong‐Bing Yao, Cheng Chen   +2 more
wiley   +1 more source

Triptolide Suppresses Tongue Squamous Cell Carcinoma Progression via PI3K–AKT Pathway Inhibition: An Integrative Network Pharmacology and Experimental Validation Study

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Tongue squamous cell carcinoma, the most aggressive subtype of oral squamous cell carcinoma, which is associated with high mortality, frequent recurrence, and early lymph‐node metastasis. Triptolide, a bioactive diterpenoid from Tripterygium wilfordii, exhibits broad anticancer activity.
Shan‐Shan Wang, Hong‐Cheng Wei, Lin Jiang, Yi‐Sen Shao   +3 more
wiley   +1 more source

Superior Labial Artery Flap for Septal Perforation Repair: The Boxer's Flap

The Laryngoscope, EarlyView.
The nasal floor flap, or Boxer's flap, is an anteriorly pedicled, superior labial artery–based mucosal flap that provides excellent closure rates in septal perforation repair when traditional septal flaps are not feasible. The schematic shows: (A) preoperative perforation, (B) nasal floor flap elevation (with the pedicle maintained at the inferior ...
Nicholas J. Campion, Zhanna Mokoyan, Viktoriya Stepanova, Isam Alobid, Richard J. Harvey, Yury Rusetsky   +5 more
wiley   +1 more source