Results 151 to 160 of about 62,023 (261)

Toxicity Differences Between Microplastics and Nanoplastics in Organs: From Molecular Mechanisms to Potential Therapeutic Strategies

Med Research, EarlyView.
This review systematically compares the size‐dependent toxicity of microplastics and nanoplastics in the intestine, liver, kidney, lung, and brain. Particle size determines bioavailability, barrier penetration, and injury mechanisms. Because of their small size and high surface reactivity, NPs readily cross the intestinal epithelium and blood–brain ...
Yixian Cheng, Junjie Chen, Rui Fu, Jiawei Zhang, Jianguang Jia, Wei Wang, Zheng Zhang, Peng Zhang, Haosong Chen, Huake Cao, Gang Li, Weiwei Sheng, Ting Li, Bo Chen, Guodong Cao   +14 more
wiley   +1 more source

Untargeted Metabolomics of Human Airway Epithelium Reveals Neuroactive Signatures Linked to Pulmonary Neuroendocrine Cell Enrichment and Allergen Exposure. [PDF]

Metabolites
Mann-Nüttel R, Diya A, Forsythe P.
europepmc   +1 more source

Redefining CHI3L1: Therapeutic Opportunities at the Crossroads of Immune Suppression and Disease Progression

Medicinal Research Reviews, EarlyView.
ABSTRACT Chitinase‐3‐like‐1 (CHI3L1, also known as YKL‐40) has been recognized as a biomarker of inflammation and tissue remodeling and has now emerged as a pseudoenzymatic immune checkpoint. Recent structural, immunological, and translational studies redefine it as an active regulator of immune suppression rather than a passive disease marker. Despite
Kirti Upmanyu, Saurabh Upadhyay, Moustafa T. Gabr   +2 more
wiley   +1 more source

Innate epithelial and functional differences in airway epithelium of children with acute wheeze. [PDF]

Front Cell Dev Biol
Looi K, Iosifidis T, Harrison S, Stick SM, LeSouef P, Laing IA, Kicic A.   +6 more
europepmc   +1 more source

Feasibility and SNR Performance of Hyperpolarized 129Xe Gas Exchange Imaging Using a Balanced SSFP Sequence

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To develop a balanced SSFP (bSSFP) sequence for pulmonary 129Xe dissolved‐phase imaging based on a previously described double‐echo sequence facilitating separation into red blood cell and membrane signals, to test its feasibility and compare its SNR performance and imaging results to an analogous FLASH sequence.
Agilo L. Kern, Marcel Gutberlet, Jens M. Hohlfeld, Frank Wacker, Jens Vogel‐Claussen   +4 more
wiley   +1 more source

Next Decade Research in Asthma: Broad Omics-Based Exploration Versus Targeted Airway Epithelium Studies. [PDF]

J Clin Med
Picado C, Garcia de la Fuente A, Arismendi E, Roca-Ferrer J.   +3 more
europepmc   +1 more source

Myasthenia Gravis and Thymoma

Muscle &Nerve, EarlyView.
ABSTRACT Thymoma is the most common tumor of the anterior mediastinum. Approximately 20%–30% of patients with a thymoma develop myasthenia gravis (MG), and an additional one third may possess positive acetylcholine receptor (AChR) antibodies without MG.
Benjamin Claytor, Lukas Delasos, Daniel P. Raymond, Erik Seroogy, Jason Lempel, Yuebing Li   +5 more
wiley   +1 more source

Mitochondrial targeting by measles virus nucleoprotein modulates viral spread in human airway epithelium. [PDF]

PLoS Pathog
Durnell-Bettis LA, Clark SE, Hippee CE, Liu A, Kaufman JW, Winecke SR, Yadav K, Singh BK, Cattaneo R, Sinn PL.   +9 more
europepmc   +1 more source

Congenital Intraoral Synechiae: A Scoping Review of Airway, Feeding, and Surgical Management

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To map the existing literature on congenital intraoral synechiae and summarize reported anatomic patterns, clinical presentation, associated anomalies/syndromes, and outcomes to inform standardized diagnostic and therapeutic approaches. Data Sources PubMed, CINAHL, Embase, Web of Science, and Google Scholar were searched from January
Jason Bernier, Mathieu Bergeron
wiley   +1 more source

Host transcriptomic analysis reveals a defective intracellular environment that limits SARS-CoV-2 replication in CFTR-deficient airway epithelium. [PDF]

Front Cell Infect Microbiol
Lagni A, Lotti V, Cecchetto R, Tonon E, Diani E, Palmisano A, Piccaluga PP, Calgaro M, Vitulo N, Sorio C, Gibellini D.   +10 more
europepmc   +1 more source