Results 11 to 20 of about 67,377 (251)

Engineering Airway Epithelium [PDF]

Journal of Biomedicine and Biotechnology, 2012
Airway epithelium is constantly presented with injurious signals, yet under healthy circumstances, the epithelium maintains its innate immune barrier and mucociliary elevator function. This suggests that airway epithelium has regenerative potential (I. R. Telford and C. F. Bridgman, 1990).
John P. Soleas, Ana Paz, Paula Marcus, Alison McGuigan, Thomas K. Waddell   +4 more
core   +6 more sources

Apoptosis and the Airway Epithelium [PDF]

Journal of Allergy, 2011
The airway epithelium functions as a barrier and front line of host defense in the lung. Apoptosis or programmed cell death can be elicited in the epithelium as a response to viral infection, exposure to allergen or to environmental toxins, or to drugs.
Steven R. White
openaire   +3 more sources

Function of the airway epithelium in asthma. [PDF]

Journal of biological regulators and homeostatic agents, 2012
Asthma is traditionally defined as a chronic disease characterized by bronchial hyper-responsiveness and lung inflammation. The airway inflammation and remodelling together likely explain the clinical manifestations of asthma. The mechanisms by which the external environmental cues, together with the complex genetic actions, propagate the inflammatory ...
LEONARDI, SALVATORE, Vitaliti G, Marseglia GL, Caimmi D, Lionetti E, Miraglia del Giudice M, Salpietro C, Spicuzza L, Ciprandi G, La Rosa M.   +9 more
core   +10 more sources

Plasticity in the airway epithelium

American Journal of Physiology-Lung Cellular and Molecular Physiology, 1990
Normal cell turnover as well as the response to injury require cell proliferation and differentiation. The airway epithelium maintains these processes throughout adult life. Controlled homeostatically, cell proliferation and differentiation usually restore, as an end point, the pseudostratified architecture of the normal mucociliary epithelium.
C, Basbaum, B, Jany
openaire   +3 more sources

Innate Immune Responses of the Airway Epithelium

Molecules and Cells, 2010
Barrier epithelia, especially airway epithelial cells, are persistently exposed to micro-organisms and environmental factors. To protect the host from these microbial challenges, many immune strategies have evolved. The airway epithelium participates in the critical innate immune response through the secretion of immune effectors such as mucin ...
Ji-Hwan, Ryu, Chang-Hoon, Kim, Joo-Heon, Yoon   +2 more
openaire   +4 more sources

[Regeneration of injured airway epithelium].

Annales pharmaceutiques francaises, 2006
The airway surface epithelium is frequently injured by microorganisms and viruses due to its permanent contact with the external medium. Following injury, the epithelium is able to repair itself and regenerate through several mechanisms including spreading and migration of basal cells, cell proliferation and differentiation.
Puchelle, Edith, Le Simple, Pierre, Hajj, Rodolphe, Coraux, Christelle   +3 more
core   +4 more sources

Influence of Hypoxia on the Airway Epithelium. [PDF]

Physiol Res
The necessity of oxygen for metabolic processes means that hypoxia can lead to serious cell and tissue damage. On the other hand, in some situations, hypoxia occurs under physiological conditions and serves as an important regulation factor. The airway epithelium is specific in that it gains oxygen not only from the blood supply but also directly from ...
Procházková K, Uhlík J.
europepmc   +3 more sources

Taste Receptors: The Gatekeepers of the Airway Epithelium [PDF]

Cells, 2021
Taste receptors are well known for their role in the sensation of taste. Surprisingly, the expression and involvement of taste receptors in chemosensory processes outside the tongue have been recently identified in many organs including the airways. Currently, a clear understanding of the airway-specific function of these receptors and the endogenous ...
Martens, Katleen, Steelant, Brecht, Bullens, Dominique M.A.   +2 more
openaire   +5 more sources

Human airway xenograft models of epithelial cell regeneration [PDF]

, 2000
Regeneration and restoration of the airway epithelium after mechanical, viral or bacterial injury have a determinant role in the evolution of numerous respiratory diseases such as chronic bronchitis, asthma and cystic fibrosis.
Puchelle Edith, Puchelle, Edith, Peault Bruno, Edith Puchelle, Bruno Peault, Peault, Bruno   +5 more
core   +1 more source

Urinary CC16 after challenge with dry air hyperpnoea and mannitol in recreational summer athletes [PDF]

, 2013
Airway epithelial injury is regarded as a key contributing factor to the pathogenesis of exercise-induced bronchoconstriction (EIB) in athletes. The concentration of the pneumoprotein club cell (Clara cell) CC16 in urine has been found to be a non ...
Pascale Kippelen, Leena Ali, Ali, Leena, Anderson, Sandra D., Bjermer, Leif, Tufvesson, E, Bjermer, L, Tufvesson, Ellen, Ali, L, Kippelen, P, Kippelen, Pascale, Leif Bjermer, Sandra D. Anderson, Anderson, SD, Ellen Tufvesson   +14 more
core   +1 more source