Results 221 to 230 of about 60,557 (265)
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Airway epithelium and bronchial reactivity
Canadian Journal of Physiology and Pharmacology, 1987Damage to or dysfunction of respiratory epithelial cells may contribute to the etiology of bronchial hyperreactivity in asthma and airway infection. In the vascular system, endogenous neurohumoral mediators can cause either relaxation or contraction of the smooth muscle of the blood vessel wall because they cause the release of relaxing or contracting
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In vivo restitution of airway epithelium
Cell & Tissue Research, 1995Epithelial shedding occurs in health and, extensively, in inflammatory airway diseases. This study describes deepithelialisation, reepithelialisation and associated events in guinea-pig trachea after shedding-like epithelial denudation in vivo. Mechanical deepithelialisation of an 800-microns wide tracheal zone was carried out using an orotracheal ...
J S, Erjefält +3 more
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The airway epithelium in childhood asthma
Journal of Allergy and Clinical Immunology, 2012There has been a focus for more than 40 years on the bronchial epithelium as an important structure in initiating the physiologic and clinical abnormalities of asthma. This makes sense because the bronchial epithelium is the initial barrier met by all inhaled irritants, toxins, or allergens, and the bronchial epithelium’s response to these noxious ...
O'Byrne, Paul M, Pedersen, Søren
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Non-neuronal cholinergic airway epithelium biology
Current Opinion in Pharmacology, 2014Acetylcholine, a major regulator of airway function, is not solely produced by neurons but also by a variety of non-neurons cells including various airway epithelial cells utilizing a molecular machinery of acetylcholine synthesis and release that differs from that of neurons.
Wolfgang, Kummer +1 more
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Water permeability in human airway epithelium
Pflügers Archiv - European Journal of Physiology, 2005Osmotic water permeability (P(f)) was studied in spheroid-shaped human airway epithelia explants derived from nasal polyps by the use of a new improved tissue collection and isolation procedure. The fluid-filled spheroids were lined with a single cell layer with the ciliated apical cell membrane facing the outside.
Pedersen, Peter Steen +4 more
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Creatine Activates Airway Epithelium in Asthma
International Journal of Sports Medicine, 2010Airway epithelium plays important roles in the pathophysiology of asthma. Creatine supplementation (Cr) was shown to increase asthma features in a murine model of allergic asthma; however, the role of the airway epithelium in this inflammatory response is not known.
Ferreira, Sérgio César +8 more
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Cell Jamming in the Airway Epithelium
Annals of the American Thoracic Society, 2016Hallmarks of asthma include chronic airway inflammation, progressive airway remodeling, and airway hyperresponsiveness. The initiation and perpetuation of these processes are attributable at least in part to critical events within the airway epithelium, but the underlying mechanisms remain poorly understood.
Jin-Ah, Park, Jeffrey J, Fredberg
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1992
Ciliated cells and goblet cells are the cells most exposed to external noxae, and thus more subject to damage. In chronic bronchitic disease and in other pulmonary diseases in which there is abnormal mucus production, the goblet cells appear swollen and increased in number, while cilia are often nonuniformly glued to each other by mucus.
P. C. Braga, L. Allegra, G. Piatti
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Ciliated cells and goblet cells are the cells most exposed to external noxae, and thus more subject to damage. In chronic bronchitic disease and in other pulmonary diseases in which there is abnormal mucus production, the goblet cells appear swollen and increased in number, while cilia are often nonuniformly glued to each other by mucus.
P. C. Braga, L. Allegra, G. Piatti
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Azithromycin ameliorates airway remodeling via inhibiting airway epithelium apoptosis
Life Sciences, 2017Azithromycin can benefit treating allergic airway inflammation and remodeling. In the present study, we hypothesized that azithromycin alleviated airway epithelium injury through inhibiting airway epithelium apoptosis via down regulation of caspase-3 and Bax/Bcl2 ratio in vivo and in vitro.Ovalbumin induced rat asthma model and TGF-β1-induced BEAS-2B ...
Yuanqi, Liu +4 more
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[Regeneration of injured airway epithelium].
Annales pharmaceutiques francaises, 2006The airway surface epithelium is frequently injured by microorganisms and viruses due to its permanent contact with the external medium. Following injury, the epithelium is able to repair itself and regenerate through several mechanisms including spreading and migration of basal cells, cell proliferation and differentiation.
Puchelle, Edith +3 more
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