Results 131 to 140 of about 162,572 (266)

GDNF-RET signaling drives pulmonary neuroendocrine cell hyperplasia and allergic airway inflammation. [PDF]

FEBS Lett
Kawano T, Ike E, Okada S, Takahashi T.
europepmc   +1 more source

RORγt‐APCs: The New Masters of Oral Tolerance

Barrier Immunity, EarlyView.
ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley   +1 more source

Synergistic interactions of melatonin and glucocorticoids in alleviating allergic airway inflammation. [PDF]

Front Med (Lausanne)
Zhang Z, Wang J, Ma T, Zhang X, Chen G, Wang B.   +5 more
europepmc   +1 more source

Novel Organelle‐Based Intracellular Immunity With Mechanistic and Therapeutic Implications

Barrier Immunity, EarlyView.
A conceptual framework illustrating how PAMPs/DAMPs initiate barrier, innate, adaptive, and intracellular immune responses, with organelle‐based intracellular immunity serving as a central integrator linking metabolism, inflammatory signaling, and therapeutic interventions to restore immune homeostasis.
Keman Xu, Shih‐Yu Hung, Fatma Saaoud, Ying Shao, Yifan Lu, Juanjuan Liu, Bo Yuan, Haiyan Xiang, Hong Wang, Xiaofeng Yang   +9 more
wiley   +1 more source

Loss of POGLUT2/3‐mediated O‐glucosylation produces lung and aortic phenotypes reminiscent of fibrillin1 mutants

Developmental Dynamics, EarlyView.
Abstract Background Fibrillins provide a scaffold for elastic fiber formation, which enables lung recoil and aortic compliance. Abnormal fibrillin microfibrils, as in Marfan syndrome, lead to enlarged alveoli, vascular stiffening, and aneurysms. Our earlier studies suggested that fibrillin function depends on O‐glucosylation of its epidermal growth ...
Sanjiv Neupane, Angelina Almiroudis, Kaitlyn E. Donnelly, Robert S. Haltiwanger, Bernadette C. Holdener   +4 more
wiley   +1 more source

KAT8 drives M2 macrophage polarization to exacerbate allergic airway inflammation. [PDF]

iScience
Lai X, Li H, Zhao Z, Zhong Y, Su G, Huang J, Xiang Y, Huang R, Quan J, Feng Z, Fang Z, Li S, Huang T, Xiong Z, Lei Y, Zhang W, Duan J, Gao X, Lai T.   +18 more
europepmc   +1 more source

Human Metapneumovirus and Its Association With Otorhinolaryngological Manifestations: A Systematic Review With Descriptive Synthesis

Eye &ENT Research, EarlyView.
ABSTRACT Human metapneumovirus (HMPV) is a respiratory virus that predominantly affects the pediatric population. Its role as an infective agent in ear, nose, and throat (ENT) diseases is not yet well understood. To systematically review the available literature on the association between HMPV and ENT manifestations, following PRISMA guidelines, a ...
Ali Gohar, Muhammad Husnain Ahmad, Hamza Zaheer, Fizza Inam, Moeez Ahmad Saeed, Nimra Mehmood, Abdul Rehman Shahid Khan, Alishbah Saeed, Hanzala Zahid, Yashika Gupta, Muhammad Bilal Akram, Habban Ghani, Muhammad Ahmad Farooq   +12 more
wiley   +1 more source

Helper T cells and chemokines in elderly asthma - Mechanisms of airway inflammation and remodeling: A review. [PDF]

Biomol Biomed
Wu Y.
europepmc   +1 more source

Biomarkers of lung congestion and injury in acute heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 781-789, April 2025.
Abstract Acute heart failure (AHF) classification and management are primarily based on lung congestion and/or hypoperfusion. The quantification of the vascular and tissue lung damage is not standard practice though biomarkers of lung injury may play a relevant role in this context.
Marco Guazzi, Gabriele Novello, Francesca Bursi, Anna Caretti, Noemi Furlotti, Ross Arena, Paola Argiento, Julio Núñez, Antoni Bayes‐Genis, Marco Metra   +9 more
wiley   +1 more source

Ginkgolide B Alleviates Airway Inflammation in Hyperoxia Lung Injury. [PDF]

Immun Inflamm Dis
Wang X, Chen M, Lv Y, Qi Y, Huang D, Wang S.   +5 more
europepmc   +1 more source