Results 91 to 100 of about 397,469 (244)
Airway remodeling in asthma: new insights
, 2003 Asthma is increasing in prevalence worldwide as a result of factors associated with a Western lifestyle. The prevalence and chronic nature of the disease represent significant economic burdens.
Powell, Robert M. +4 more
core +1 more source
The contribution of L-selectin to airway hyperresponsiveness in chronic allergic airways disease
Journal of Asthma and Allergy, 2010 Simon G Royce, Melissa Lee, Mimi L K TangDepartment of Allergy and Immunology, Murdoch Children’s Research Institute, The Royal Children’s Hospital, Parkville, Victoria 3052, AustraliaAbstract: L-selectin is a cell adhesion molecule ...
Simon G Royce +2 more
doaj
Type 2 Cytokines in the Pathogenesis of Sustained Airway Dysfunction and Airway Remodeling in Mice
, 2015 The mechanisms underlying airway hyperresponsiveness remain unclear, although airway inflammation and remodeling likely play important roles. We have observed sustained airway hyperreactivity and airway remodeling occurring in mice after chronic ...
Inman, Mark +7 more
core
Immune induction of airway remodeling
, 2019 Airway remodeling is accepted to be a determining component within the natural history of asthma. It is a phenomenon characterized by changes in the airways structures that marches in parallel with and can be influenced by airway inflammation, floating ...
Riccio A. M., Guida G., Guida, G.
core +1 more source
Three‐dimensional geometric morphometric analysis of diaphragmatic dome motion in COPD patients
The Anatomical Record, EarlyView.Abstract Diaphragmatic dysfunction is a hallmark of chronic obstructive pulmonary disease (COPD), especially in emphysema, where hyperinflation alters diaphragm geometry and impairs inspiratory mechanics. However, quantitative three‐dimensional (3D) assessments of diaphragmatic dome shape and motion across COPD phenotypes are limited.
José M. López‐Rey +5 more
wiley +1 more source
PLoS ONE, 2014 The liver-X-receptors have shown anti-inflammatory ability in several animal models of respiratory disease. Our purpose is to investigate the effect of LXR ligand in allergen-induced airway remodeling in mice.
Ying Shi +5 more
doaj +1 more source
, 2012 Airway diseases such as chronic rhinosinusitis, asthma, and chronic obstructive pulmonary disorder are characterized by inflammation and remodeling. Among inflammatory and extracellular matrix regulatory cytokines, transforming growth factor-beta (TGF ...
Hu, GH +8 more
core +1 more source
The Anatomical Record, EarlyView.Abstract Sequence variations in fibroblast growth factor receptor 2 (FGFR2) are associated with craniosynostosis syndromes, disrupting craniofacial development, yet early mandibular alterations remain poorly characterized. This study examined Meckel's cartilage (MC) and mandibular morphology in mouse models of Apert (Fgfr2+/P253R) and Crouzon ...
Fred R. Foster +7 more
wiley +1 more source
Arthritis &Rheumatology, EarlyView.Objective Rheumatoid arthritis (RA) often involves extra‐articular complications, including interstitial lung disease (ILD) and/or pulmonary nodules. Transcriptomic profiling of lung tissue provides the opportunity to directly assess cell‐specific gene expression and corresponding pathway activation in different types of rheumatoid lung disease ...
Tracy Tabib +8 more
wiley +1 more source
Arthritis &Rheumatology, EarlyView.Objective Tissue‐specific biomarkers that are reliable and associated with clinical manifestations of idiopathic inflammatory myopathy (IIM) are lacking. The blood circulation in individuals serves as a central conduit, allowing communication between tissues and facilitating clearance and recycling of tissue‐derived proteins.
Yue‐Bei Luo +23 more
wiley +1 more source