Results 71 to 80 of about 365,854 (289)
Journal of International Medical Research, 2022 Omalizumab is used for the treatment of persistent severe allergic asthma in adults and children. However, some patients remain symptomatic even after omalizumab treatment. In bronchial asthma, chronic inflammation of the bronchial wall causes thickening
Mitsuru Tsuge +3 more
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A new series on airway remodelling [PDF]
European Respiratory Journal, 2007 In today's respiratory research, airway remodelling is probably one the best examples of an area for which the level of excitement easily matches the level of confusion on its definition and implication. This seeming contradiction may, however, not be worrying at all in science. In fact, it is likely to be a powerful driving force of creative research,
Boulet, L.-P., Sterk, P. J.
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Review of the Molecular and Developmental Basis of Myhre Syndrome, Bench Research
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.ABSTRACT Myhre syndrome (MS) is a connective‐tissue disorder within the acromelic dysplasia spectrum. It is characterized by congenital craniofacial, skeletal, cutaneous anomalies, respiratory, cardiovascular along with intellectual disability, deafness, and progressive fibrosis.
Camille Viaut, Valerie Cormier‐Daire
wiley +1 more source
Human Vaccines & Immunotherapeutics, 2017 Bacillus Calmette-Guerin (BCG) is a potent agent for the prevention of tuberculosis. Current studies have regarded BCG as an immunomodulator. However, there is little information on whether it can be used to inhibit airway inflammation and airway ...
Xinrui Tian +7 more
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CTGF upregulation correlates with MMP-9 level in airway remodeling in a murine model of asthma
, 2016 Introduction : Connective tissue growth factor (CTGF) mediates hypertrophy, proliferation, and extracellular matrix synthesis. Matrix metalloproteinase (MMP) plays a role in airway extracellular matrix remodeling.
Bor-Luen Chiang +3 more
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Posthumously Diagnosed Myhre Syndrome Presenting With Pleural Remodeling and Endometrial Cancer
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.ABSTRACT Myhre syndrome (OMIM 139210) is a genetic condition defined by neurodevelopmental disability, characteristic facial features, and multisystem proliferative fibrosis. While various types of lung disease have been reported, pleural remodeling leading to restrictive lung disease has not yet been described.
Jeanette Saffir +6 more
wiley +1 more source
Mechanisms altering airway smooth muscle cell Ca(2+) homeostasis in two asthma models [PDF]
, 2008 Background: Asthma is characterized by airway remodeling, altered mucus production and airway smooth muscle cell (ASMC) contraction causing extensive airway narrowing. In particular, alterations of ASMC contractility seem to be of crucial importance. The
Kellner, Julia +6 more
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Inhibition of Orai-STIM coupling alleviates experimentally-induced airways remodeling changes
Revista Alergia México, 2018 Background: In asthma, airway remodeling changes contribute to thickening of airway walls and, consequently, lead to poor clinical outcomes among asthmatic patients.
Martina Sutovska, Sona Franova
doaj
Pathological airway remodelling in inflammation [PDF]
The Clinical Respiratory Journal, 2010 AbstractIntroduction: Airway remodelling refers to a wide pattern of patophysiological mechanisms involving smooth muscle cell hyperplasia, increase of activated fibroblasts and myofibroblasts with deposition of extracellular matrix. In asthma, it includes alterations of the epithelial cell layer with goblet cell hyperplasia, thickening of basement ...
Gunilla, Westergren-Thorsson +6 more
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International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Introduction Temperature‐controlled radiofrequency (TCRF), septoplasty (ST) with turbinate reduction, and functional rhinoplasty (FR) are treatment options for nasal airway obstruction (NAO) and nasal valve dysfunction (NVD), but no direct comparison of these procedures has been performed. Methods This prospective, open‐label, non‐inferiority (
Greg Davis +13 more
wiley +1 more source