Results 151 to 160 of about 365,854 (289)
Type 2 Cytokines in the Pathogenesis of Sustained Airway Dysfunction and Airway Remodeling in Mice
, 2015 The mechanisms underlying airway hyperresponsiveness remain unclear, although airway inflammation and remodeling likely play important roles. We have observed sustained airway hyperreactivity and airway remodeling occurring in mice after chronic ...
Inman, Mark +7 more
core
Inflammatory Shift in Chronic Rhinosinusitis Amidst Guangzhou's Urbanization (2000–2018)
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Background Chronic rhinosinusitis (CRS) exhibits temporal and geographic diversity in pathological endotypes with progressive eosinophilic infiltration, while the underlying causes remain unclear. Current pathological endotypes determination relies on mean cell count per high‐power field, requiring accuracy optimization.
Ning Kang +16 more
wiley +1 more source
Targeting Airway Remodeling in Severe Asthma: Is There a Window of Opportunity for Biologic Therapy Predicting Effects Using Causal Artificial Intelligence? [PDF]
AllergyGangemi S +3 more
europepmc +1 more source
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Objective Budesonide is a corticosteroid with unique pharmacokinetic and pharmacodynamic properties that has been a frontline treatment for patients with allergic rhinitis (AR) and chronic rhinosinusitis (CRS) since the 1990s. As research on budesonide continues to produce new insights, our aim was to synthesize recent investigations and ...
David W. Kennedy +2 more
wiley +1 more source
Integrated airway epithelial signaling networks linking allergen-driven inflammation to airway remodeling in asthma. [PDF]
Front ImmunolPark SY.
europepmc +1 more source
An in vitro airway wall model of remodeling
Recent studies have shown that mechanical forces on airway epithelial cells can induce upregulation of genes involved in airway remodeling in diseases such as asthma.
Swartz, M. A., Choe, M. M., Sporn, P. H.
core +1 more source
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by inflammatory heterogeneity, epithelial hyperplasia, and tissue remodeling, with spatial pathology critical for deciphering pathological mechanisms and guiding clinical practice.
Zi‐Xuan Hua +12 more
wiley +1 more source
Jinshui Liujun Decoction attenuates cigarette smoke-induced small airway remodeling via the TGF-β/Smad2/CFTR Axis. [PDF]
J Physiol SciLiu Y, Xie W, Zhou Q, Ouyang G.
europepmc +1 more source
The Global Airways Unit: A Multidisciplinary Strategy for Early Diagnosis and Comorbidity Detection
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Background Chronic respiratory diseases impose a large global burden of morbidity, mortality, and cost. The concept of a global airway has become increasingly supported by epidemiologic, mechanistic, and clinical evidence. However, clinical care often remains fragmented between ear, nose, and throat (ENT), allergy, and pulmonology.
Diego M. Conti +16 more
wiley +1 more source