Inflammatory Shift in Chronic Rhinosinusitis Amidst Guangzhou's Urbanization (2000–2018)
ABSTRACT Background Chronic rhinosinusitis (CRS) exhibits temporal and geographic diversity in pathological endotypes with progressive eosinophilic infiltration, while the underlying causes remain unclear. Current pathological endotypes determination relies on mean cell count per high‐power field, requiring accuracy optimization.
Ning Kang +16 more
wiley +1 more source
LAMC2 Drives Airway Remodeling in COPD via EMT Regulation Through the AKT Pathway. [PDF]
Wang Z +7 more
europepmc +1 more source
Asthma: a disease remodeling the airways [PDF]
J, Bousquet +6 more
openaire +2 more sources
Phenotyping Preeclampsia Using Unsupervised Machine Learning: A Prospective Cohort Study
ABSTRACT Objective To explore clinically meaningful phenotypes of preeclampsia using unsupervised machine learning. Design Prospective cohort study. Setting BCNatal, a tertiary maternal‐foetal medicine centre (Barcelona, Spain). Population A total of 482 pregnant women diagnosed with preeclampsia between August 2013 and April 2024.
Ohad Houri +18 more
wiley +1 more source
Osteopontin deficiency protects against airway remodeling and hyperresponsiveness in chronic asthma
Rationale: Osteopontin (OPN) is a cytokine that is upregulated in epithelial cells and macrophages in the lungs of mice during chronic allergen challenge and airway remodeling and also in lungs of patients with asthma. However, it remains unclear whether
Xanthou, G. +5 more
core
Electroacupuncture modulates gut-lung microbiota and lung EMT to attenuate airway remodeling in COPD. [PDF]
Chen D +5 more
europepmc +1 more source
Early Intervention With Biologics for Asthma Remission: Promising or Premature?
Respirology, EarlyView.
Santi Nolasco +2 more
wiley +1 more source
Cardiovascular Plasticity and Adaptation of High‐Altitude Birds and Mammals
This schematic depicts the cardiovascular adaptations of mammals and birds to high‐altitude hypoxia. It highlights key phenotypic changes in oxygen transport and cardiac responses, driven by molecular mechanisms including transcriptional regulation and genetic modifications.
Huishang She, Yanhua Qu
wiley +1 more source
Cuproptosis of bronchial epithelial cells triggers airway remodeling in chronic asthma. [PDF]
Wang M +5 more
europepmc +1 more source
Sequence of Immunological Events During IgE‐Mediated Allergic Reactions to Food
ABSTRACT Food allergies (FA) represent a significant global health burden. Upon allergen re‐exposure, allergic patients exhibit a sequence of symptoms that vary in terms of affected organ systems, severity, time of onset and allergen reactivity thresholds.
N. A. Nagy +7 more
wiley +1 more source

