Results 161 to 170 of about 397,469 (244)

Inflammatory Shift in Chronic Rhinosinusitis Amidst Guangzhou's Urbanization (2000–2018)

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) exhibits temporal and geographic diversity in pathological endotypes with progressive eosinophilic infiltration, while the underlying causes remain unclear. Current pathological endotypes determination relies on mean cell count per high‐power field, requiring accuracy optimization.
Ning Kang, Man‐Hou Chao, Xin Luo, Feng‐Wen Shan, Zi‐Xuan Hua, Ze‐Zhi Guo, Hua‐Mei Yan, He Zhang, Tong Wu, Min Zhou, Rui Zheng, Shuo Wu, Xue‐Kun Huang, Zhao‐Hui Shi, Ya‐Na Zhang, Ji Yang, Qin‐Tai Yang   +16 more
wiley   +1 more source

Polydatin Relieves Airway Remodeling by Inhibiting P2X7R-NLRP3-Mediated Excessive Autophagy in Asthma. [PDF]

Immun Inflamm Dis
Li G, Li L, Wang Z, Piao Y, Song Y, Li L, Xu C, Li X, Yan G.   +8 more
europepmc   +1 more source

Safety, Efficacy, and Mechanism of Action of Budesonide in Rhinitis and Rhinosinusitis: A Systematic Review

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Budesonide is a corticosteroid with unique pharmacokinetic and pharmacodynamic properties that has been a frontline treatment for patients with allergic rhinitis (AR) and chronic rhinosinusitis (CRS) since the 1990s. As research on budesonide continues to produce new insights, our aim was to synthesize recent investigations and ...
David W. Kennedy, Lei Cheng, De‐Yun Wang   +2 more
wiley   +1 more source

TGF‑β1 in obstructive sleep apnea: linking intermittent hypoxia, upper‑airway remodeling, and systemic comorbidities. [PDF]

Sleep Breath
Yuan S, Yan R, Li W, Hua M.
europepmc   +1 more source

The Global Airways Unit: A Multidisciplinary Strategy for Early Diagnosis and Comorbidity Detection

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic respiratory diseases impose a large global burden of morbidity, mortality, and cost. The concept of a global airway has become increasingly supported by epidemiologic, mechanistic, and clinical evidence. However, clinical care often remains fragmented between ear, nose, and throat (ENT), allergy, and pulmonology.
Diego M. Conti, Eduardo J. Correa, Alfonso Del Cuvillo, José D. Abdullatif, Francisco J. Alvarez‐Gutiérrez, Remedios Cárdenas Contreras, Stefan Cimbollek, Rocío Corrales Millán, Ana Gómez‐Bastero Fernández, Daniel Pérez‐Chada, Francisco Pérez‐Grimaldi, Alberto E. Rabino, Maria A. Romero‐Falcón, Marcela Soria, José Gregorio Soto‐Campos, Rosario B. Spuches, Juan Maza‐Solano   +16 more
wiley   +1 more source

Correction: Macrophage migration inhibitory factor exacerbates asthmatic airway remodeling via dynamin-related protein 1-mediated autophagy activation. [PDF]

Respir Res
Liu J, Chen Y, Chen H, Wang Y, Li D, Zhang Q, Chai L, Qiu Y, Zhang J, Shen N, Wang Q, Wang J, Li M.   +12 more
europepmc   +1 more source

Where Eastern Medicine Meets Western Medicine: A World Review of the Management of Chronic Cough

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Purpose To summarize current Western and Eastern approaches to the evaluation and management of chronic cough, with particular emphasis on etiology‐directed therapy, cough hypersensitivity, behavioral interventions, neuromodulators, procedural treatments, and traditional remedies.
Thomas Zheng Jie Teng, Zhi Xuan Koh, Justin Yi Shen Lim, Kavimalar Ravi, Jin Wayne Kyler Ong, Christina Hui Lee Ng   +5 more
wiley   +1 more source

STING‑regulated Ca²⁺-TGF‑β axis drives airway remodeling and lung function decline in asthma: a multi‑omics mechanistic study. [PDF]

Biol Direct
Zhu Z, Xiao Q, Cai R, Qi E, Gong X, Tang J, Li X, Feng J.   +7 more
europepmc   +1 more source

Cardiovascular Plasticity and Adaptation of High‐Altitude Birds and Mammals

Integrative Zoology, EarlyView.
This schematic depicts the cardiovascular adaptations of mammals and birds to high‐altitude hypoxia. It highlights key phenotypic changes in oxygen transport and cardiac responses, driven by molecular mechanisms including transcriptional regulation and genetic modifications.
Huishang She, Yanhua Qu
wiley   +1 more source

Dual role of IL-17A in COPD: amplifier of inflammatory cascades and mediator of airway remodeling and alveolar destruction. [PDF]

Front Immunol
Zhang L, Gu Y, Deng R, Ouyang Y.
europepmc   +1 more source