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How does cigarette smoking affect airway remodeling in asthmatics?
Tobacco Induced Diseases, 2023 Asthma is a prevalent chronic airway inflammatory disease involving multiple cells, and the prolonged course of the disease can cause airway remodeling, resulting in irreversible or partial irreversible airflow limitation and persistent airway ...
Huihui Lin, Hequan Li
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Airway remodeling heterogeneity in asthma and its relationship to disease outcomes
Frontiers in Physiology, 2023 Asthma affects an estimated 262 million people worldwide and caused over 461,000 deaths in 2019. The disease is characterized by chronic airway inflammation, reversible bronchoconstriction, and airway remodeling.
Aileen Hsieh +5 more
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Research progress on miRNA in airway remodeling [PDF]
Xin yixue, 2022 Airway remodeling refers to the structural and functional changes of airway tissues caused by repeated chronic inflammatory stimulation injury and incomplete repair.
Qiu Chenhui, Chen Ye
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Central role of cellular senescence in TSLP-induced airway remodeling in asthma. [PDF]
PLoS ONE, 2013 BACKGROUND:Airway remodeling is a repair process that occurs after injury resulting in increased airway hyper-responsiveness in asthma. Thymic stromal lymphopoietin (TSLP), a vital cytokine, plays a critical role in orchestrating, perpetuating and ...
Jinxiang Wu +8 more
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Frontiers in Genetics, 2020 Atherosclerosis is the pathological basis of cardiovascular disease. Obstructive sleep apnea (OSA) aggravates atherosclerosis, and chronic intermittent hypoxia (CIH) as a prominent feature of OSA plays an important role during the process of ...
Jing Zhang +31 more
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Canadian Respiratory Journal, 2023 Objective. Dysregulation of epithelial-mesenchymal transition (EMT) in the airway epithelium is associated with airway remodeling and the progression of pulmonary fibrosis.
Hongjuan He +6 more
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Role of Th17 Cytokines in Airway Remodeling in Asthma and Therapy Perspectives
Frontiers in Allergy, 2022 Airway remodeling is a frequent pathological feature of severe asthma leading to permanent airway obstruction in up to 50% of cases and to respiratory disability.
Victor Margelidon-Cozzolino +4 more
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Children, 2022 Anti-inflammatory therapy, centered on inhaled steroids, suppresses airway inflammation in asthma, reduces asthma mortality and hospitalization rates, and achieves clinical remission in many pediatric patients.
Mitsuru Tsuge +2 more
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Frontiers in Pharmacology, 2021 Background: Endothelial barrier dysfunction plays a key role in atherosclerosis progression. The primary pathology of obstructive sleep apnea-hypopnea syndrome is chronic intermittent hypoxia (IH), which induces reactive oxygen species (ROS ...
Linyi Li +32 more
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