Micro-Computed Tomography Based Whole Block Imaging of Asthma-Associated Airway Remodeling With Mycobacterium avium-Induced Cavity Formation: 3-Dimensional Nondestructive Analysis. [PDF]
Tsukamoto T +10 more
europepmc +1 more source
Tissue Resident Memory Cells: Friend or Foe?
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude +2 more
wiley +1 more source
IL-5 signaling in asthmatic derived fibroblasts exacerbates airway remodeling through ECM dysregulation and apoptosis resistance. [PDF]
Abujabal R +10 more
europepmc +1 more source
Immune endotypes in tuberculosis: Keys to decoding disease complexity
Abstract Tuberculosis (TB) remains a major global health challenge, with multi‐drug antibiotic regimens as the current standard of care. While effective at killing Mycobacterium tuberculosis, these treatments do not resolve persistent inflammation, prevent lung damage, or reverse immune dysregulation that contribute to poor outcomes and disease ...
Shamila D. Alipoor +4 more
wiley +1 more source
Emerging Concepts in Cytokine Regulation of Airway Remodeling in Asthma. [PDF]
Latayan J, Akkenapally SV, Madala SK.
europepmc +1 more source
Epigenetic Regulation in the Pathogenesis of Periodontitis
The aim of this narrative literature review was to identify epigenetic marks associated with periodontitis and to place them in a biological context. The literature was reviewed based on pre‐defined criteria. Cell type specific chromatin and mRNA modifications were included.
Henrik Dommisch +3 more
wiley +1 more source
Circular RNA FCHO2 promotes airway remodeling in COPD via regulating nuclear translocation of PTBP1 to repress the splicing of GRN pre-mRNA. [PDF]
Liu Y +11 more
europepmc +1 more source
Myxomatous mitral valve disease, an acquired valvular degeneration, is the most common cardiac disorder in dogs, affecting approximately 10% of dogs in primary care veterinary practice. Dogs with myxomatous mitral valve disease frequently require anaesthesia for routine procedures.
I. Levinzon +3 more
wiley +1 more source
Type 2 gene expression signature in severe asthma associates with more advanced airway remodeling. [PDF]
Jakiela B +12 more
europepmc +1 more source

