Integrated pro-resolving mechanisms: a new dimension for optimizing anti-inflammatory therapy in asthma - a review of impaired inflammation resolution in airway remodeling. [PDF]
Zhang B +5 more
europepmc +1 more source
Pharmacological Gq targeting prevents asthmatic airway remodeling. [PDF]
Dietrich JM +7 more
europepmc +1 more source
GLCCI1 alleviates airway remodeling in asthmatic mice by inhibiting ZEB1-mediated epithelial-mesenchymal transition. [PDF]
Yang Q, Wang W, Zhu G, Xun H, Xun Q.
europepmc +1 more source
Long Non‐Coding RNA, Like NEAT1 and MALAT1, in Asthma: Mechanisms and Therapeutic Potential
Long non‐coding RNA, like NEAT1 and MALAT1, is emerging as a regulator of asthma‐related inflammation, airway remodelling, viral responses and cell death pathways, and are promising targets for future therapeutics. ABSTRACT Asthma affects millions worldwide. Long non‐coding RNA (lncRNA) are emerging as important factors in the pathophysiology of asthma
Ashlyn Poole +4 more
wiley +1 more source
Mesenchymal stem cell-derived exosomes: a new hope for improving asthma airway remodeling. [PDF]
Suo R +6 more
europepmc +1 more source
Smad7 ameliorate small airway remodeling in COPD by modulating epithelial-mesenchymal transition. [PDF]
Liu X, Sun S, He S, Xie L.
europepmc +1 more source
Distinct long-term effects on lung function and airway remodeling in ovalbumin and house dust mite mouse models of experimental asthma. [PDF]
Markus MA, Albers J, Alves F, Dullin C.
europepmc +1 more source
Human iPSC‐Derived Vascularised Lung Organoids for Modelling COPD and Pulmonary Hypertension
Vascularised lung organoids (vLOs) that faithfully mimic human lung tissue architecture and disease pathology are critical for advancing pulmonary research but remain challenging to generate. Here, we developed a robust self‐organisation protocol to produce vLOs with cellular heterogeneity and functional vasculature. The engineered blood vessels within
Simin Jiang +14 more
wiley +1 more source
Summary Pneumolabyrinth, which is the presence of gas within the labyrinth of the inner ear, can be associated with severe peripheral vestibular signs. This report describes a case of pneumolabyrinth in a horse that presented with vestibular ataxia. An 8‐year‐old Quarter Horse mare that presented with cranial nerve VII deficits underwent a standing ...
C. A. Jamieson +5 more
wiley +1 more source

