Results 201 to 210 of about 365,854 (289)

Metabolic remodelling in anthracycline cardiotoxicity: mechanisms and therapeutic insights

British Journal of Pharmacology, EarlyView.
Cardiac metabolic remodelling in anthracycline‐induced cardiomyopathy and metabolically oriented cardioprotective strategies. Schematic representation of substrate utilization, mitochondrial bioenergetic function and metabolic flexibility in the healthy heart, in anthracycline‐induced cardiomyopathy and under potential cardioprotective interventions ...
Giulia Guerra, Francesco Niro, Marco Mergiotti, Giovanni Gavatorta, Emilio Hirsch, Alessandra Ghigo   +5 more
wiley   +1 more source

Circulating Cell-Free RNA Reflects Immune-Associated and Airway Remodeling Signatures in Equine Asthma. [PDF]

J Immunol Res
Zhang B, Agdour H, Riihimäki M, Hansen S, Raine A.   +4 more
europepmc   +1 more source

IL-36 participated in airway remodeling in chronic asthma model by inducing epithelial-mesenchymal transition process. [PDF]

Eur J Med Res
Zhang M, Cen J, Gan W, Feng K, Yang H, Zou X, Li H, Zhang T.   +7 more
europepmc   +1 more source

Tezepelumab in severe asthma: chest computed tomography assessment of airway remodeling and clinical remission. [PDF]

Front Pharmacol
Lupia C, Battaglia C, Pastore D, Lee Y, Piazzetta GL, Chiarella E, Lobello N, Sireno G, Pullano A, Crimi C, Vatrella A, Manti F, Arcuri PP, Laganà D, Pelaia G, Pelaia C.   +15 more
europepmc   +1 more source

Emerging Paediatric Uses of Dupilumab Beyond Approvals

Clinical &Experimental Allergy, EarlyView.
Dupilumab, through IL‐4Rα blockade, shows promising efficacy beyond approved indications in paediatric diseases driven by T2 inflammation. Emerging evidence—mainly from small studies—supports improvements in disease severity and quality of life, highlighting its potential as a targeted, steroid‐sparing therapy while underscoring the need for ...
Simone Foti Randazzese, Anna Calamita, Diletta D'Angelo, Alessia Marseglia, Esther Mesa Lombardero, Sara Pedersoli, Micol Tedeschi, Mara De Amici, Sara Manti, Valeria Brazzelli, Amelia Licari, Gian Luigi Marseglia   +11 more
wiley   +1 more source

Integrated pro-resolving mechanisms: a new dimension for optimizing anti-inflammatory therapy in asthma - a review of impaired inflammation resolution in airway remodeling. [PDF]

Front Immunol
Zhang B, Xu Y, Song G, Sun M, Yu S, Ren M.   +5 more
europepmc   +1 more source

GLCCI1 alleviates airway remodeling in asthmatic mice by inhibiting ZEB1-mediated epithelial-mesenchymal transition. [PDF]

Respir Res
Yang Q, Wang W, Zhu G, Xun H, Xun Q.
europepmc   +1 more source

Revisiting Platelet‐Activating Factor in Asthma: An Exploratory Metabolomics Analysis of PAF C‐18:1 and Type 2 Inflammation

Allergy, EarlyView.
Noeul Kang, Young Jin Pyung, Deog Kyeom Kim, Cheol‐Heui Yun, Hyun Woo Lee   +4 more
wiley   +1 more source

Long Non‐Coding RNA, Like NEAT1 and MALAT1, in Asthma: Mechanisms and Therapeutic Potential

Clinical &Experimental Allergy, EarlyView.
Long non‐coding RNA, like NEAT1 and MALAT1, is emerging as a regulator of asthma‐related inflammation, airway remodelling, viral responses and cell death pathways, and are promising targets for future therapeutics. ABSTRACT Asthma affects millions worldwide. Long non‐coding RNA (lncRNA) are emerging as important factors in the pathophysiology of asthma
Ashlyn Poole, Ingrid Laing, Ryan Mead‐Hunter, Peter Le Souef, Guicheng Zhang   +4 more
wiley   +1 more source

Distinct long-term effects on lung function and airway remodeling in ovalbumin and house dust mite mouse models of experimental asthma. [PDF]

Sci Rep
Markus MA, Albers J, Alves F, Dullin C.
europepmc   +1 more source