Staphylococcus aureus enterotoxin B regulates prostaglandin E-2 synthesis, growth, and migration in nasal tissue fibroblasts [PDF]
, 2008 Background. Superantigens and eicosanoids are important amplifiers and regulators of inflammation in airway diseases. We therefore studied the possible influence of Staphylococcus aureus enterotoxin B ( SEB) on the cyclooxygenase ( COX) pathway and basic
Bachert, Claus +4 more
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Frontiers in Microbiology, 2021 BackgroundThe dysbiosis of respiratory microbiota plays an important role in asthma development. However, there is limited information on the changes in the respiratory microbiota and how these affect the host during the progression from acute allergic ...
Jun Zheng +5 more
doaj +1 more source
Integrating evidence for managing asthma in patients who smoke [PDF]
, 2014 Peer reviewedPublisher ...
Bjermer, Leif +3 more
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Metalloproteinases and their Inhibitors under the Course of Immunostimulation by CPG-ODN and Specific Antigen Inhalation in Equine Asthma [PDF]
, 2019 Objectives. Inhalation of immunostimulatory bacterial DNA segments (cytosine-phosphate-guanosine-oligodeoxynucleotides, CpG-ODN) normalizes clinical and cytologic parameters in severe equine asthma.
Barton, Ann Kristin +5 more
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Analysis of Differentially Expressed MicroRNAs in OVA-induced Airway Remodeling Model Mice
Iranian Journal of Allergy, Asthma and Immunology, 2022 MicroRNAs (miRNAs) can participate in airway remodeling by regulating immune molecule expression. Here, we aimed to identify the differential miRNAs involved in airway remodeling. Airway remodeling was induced by ovalbumin in female BALB/C mice.
Chang Xu +6 more
doaj +1 more source
Spatial and temporal changes in extracellular elastin and laminin distribution during lung alveolar development [PDF]
, 2018 Lung alveolarization requires precise coordination of cell growth with extracellular matrix (ECM) synthesis and deposition. The role of extracellular matrices in alveogenesis is not fully understood, because prior knowledge is largely extrapolated from ...
Chen, Hui +9 more
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Pathobiology of Airway Remodeling in Asthma: The Emerging Role of Integrins
Journal of Asthma and Allergy, 2022 Chitra Joseph, Amanda L Tatler Centre for Respiratory Research, National Institute for Health Research Biomedical Research Centre, School of Medicine, University of Nottingham, Nottingham, UKCorrespondence: Amanda L Tatler, Centre for Respiratory ...
Joseph C, Tatler AL
doaj
Aldose reductase inhibition prevents allergic airway remodeling through PI3K/AKT/GSK3β pathway in mice. [PDF]
PLoS ONE, 2013 Long-term and unresolved airway inflammation and airway remodeling, characteristic features of chronic asthma, if not treated could lead to permanent structural changes in the airways.
Umesh C S Yadav +7 more
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Tensin1 expression and function in chronic obstructive pulmonary disease [PDF]
, 2019 open access articleChronic obstructive pulmonary disease (COPD) constitutes a major cause of morbidity and mortality. Genome wide association studies have shown significant associations between airflow obstruction or COPD with a non-synonymous SNP in ...
Amrani, Y. +7 more
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Asthma remodeling: The pathogenic role of matrix metalloproteinase-9
Egyptian Journal of Chest Disease and Tuberculosis, 2014 Background: Asthma is an airway inflammatory disease with functional and structural changes, leading to bronchial hyperresponsiveness and airflow obstruction.
Amgad A. Farhat +5 more
doaj +1 more source