Results 51 to 60 of about 3,400,486 (392)

Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity. [PDF]

, 1996
Reversible airway hyperreactivity underlies the pathophysiology of asthma, yet the precise mediators of the response remain unclear. Human studies have correlated aberrant activation of T helper (Th) 2-like effector systems in the airways with disease. A
Corry, DB, Erle, DJ, Folkesson, HG, Locksley, RM, Matthay, MA, Warnock, ML, Wiener-Kronish, JP   +6 more
core  

Metformin reduces airway glucose permeability and hyperglycaemia-induced Staphylococcus aureus load independently of effects on blood glucose [PDF]

, 2013
Background Diabetes is a risk factor for respiratory infection, and hyperglycaemia is associated with increased glucose in airway surface liquid and risk of Staphylococcus aureus infection.
Ali, Bae, Baker, Baker, Barker, Bartlett, Brennan, Bubeck Wardenburg, Coyne, Dasenbrook, Deborah L Baines, Emma H Baker, Forrest, Garnett, Garnett, Garnett, Gwenan M Knight, Hallows, Hundal, James P Garnett, Jodi A Lindsay, John S Tregoning, Kalsi, Kalsi, Kapetanovic, Kennedy, Kupeli, Merlo, Myerburg, O'Neill, Peng, Pezzulo, Philips, Philips, Phillips, Radwan, Sakar, Saumon, Shore, Simren Gill, Sonam Naik, Sum, Tamer, Walker, Wood, Wu, Zhang, Zhang   +47 more
core   +1 more source

A new method for measuring airway resistance in man using a body plethysmograph: values in normal subjects and in patients with respiratory disease.

Journal of Clinical Investigation, 1956
Satisfactory methods, utilizing measurements of transthoracic or transpulmonary pressure and airflow, are now available for determining "nonelastic" pulmonary resistance.
A. Dubois, S. Botelho, J. H. Comroe
semanticscholar   +1 more source

Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery

Advanced Functional Materials, EarlyView.
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer, Min Jiang, Adrian Kromer, Anny Nguyen, Müge Molbay, Simone Pinto Carneiro, David Jürgens, Gerald Burgstaller, Bastian Popper, Benjamin Winkeljann, Olivia Monika Merkel   +10 more
wiley   +1 more source

α-Bisabolol alleviates diesel exhaust particle-induced lung injury and mitochondrial dysfunction by regulating inflammatory, oxidative stress, and apoptotic biomarkers through the c-Jun N-terminal kinase signaling pathway

Frontiers in Pharmacology
IntroductionExposure to particulate matter ≤2.5 μm in diameter (PM2.5) is associated with adverse respiratory outcomes, including alterations to lung morphology and function.
Sumaya Beegam, Nur Elena Zaaba, Ozaz Elzaki, Abderrahim Nemmar   +3 more
doaj   +1 more source

The effect on respiratory mechanics when using a Jackson surgical table in the prone position during spinal surgery [PDF]

Korean Journal of Anesthesiology, 2010
BackgroundRespiratory dynamics may be monitored and evaluated indirectly by measuring the peak inspiratory pressure and plateau pressure. In this study, the respiratory dynamics of patients undergoing spinal surgery using a Jackson surgical table were ...
Yoontae Nam, Ann Misun Yoon, Yoon Hee Kim, Seok Hwa Yoon   +3 more
doaj   +1 more source

Nonhuman Primate Models of Respiratory Disease: Past, Present, and Future. [PDF]

, 2017
The respiratory system consists of an integrated network of organs and structures that primarily function for gas exchange. In mammals, oxygen and carbon dioxide are transmitted through a complex respiratory tract, consisting of the nasal passages ...
Miller, Lisa, Pinkerton, Kent, Royer, Christopher, Schelegle, Edward   +3 more
core   +1 more source

Airways resistance and specific conductance for the diagnosis of obstructive airways diseases [PDF]

Respiratory Research, 2015
Airway resistance (RAW) and specific airway conductance (sGAW) are measures that reflect the patency of airways. Little is known of the variability of these measures between different lung diseases. This study investigated the contribution of RAW and sGAW to a diagnosis of obstructive airways disease and their role in differentiating asthma from COPD ...
Topalovic, Marko, Derom, Eric, Osadnik, Christian R., Troosters, Thierry, Decramer, Marc, Janssens, Wim, Belgian Pulmonary Function Study Investigators, Collard, Philippe, Liistro, Giuseppe, Mwenge, Gimbada Benny, Pieters, Thierry, Pilette, Charles, Pirson, Françoise, Delaunois, Luc, Marchand, Eric, Vandenplas, Olivier, Rodenstein, Daniel   +16 more
openaire   +4 more sources

Long-term Exposure to PM10 and NO2 in Association with Lung Volume and Airway Resistance in the MAAS Birth Cohort

Environmental Health Perspectives, 2013
Background: Findings from previous studies on the effects of air pollution exposure on lung function during childhood have been inconsistent. A common limitation has been the quality of exposure data used, and few studies have modeled exposure ...
Anna Mölter, R. Agius, F. de Vocht, S. Lindley, W. Gerrard, L. Lowe, D. Belgrave, A. Custovic, A. Simpson   +8 more
semanticscholar   +1 more source

An Optoelectrically Switched, Dual‐Mode Neuromorphic Sensor for Transient and Accumulative Gas Detection

Advanced Functional Materials, EarlyView.
A transistor‐type carbon nanotube gas sensor with dual‐mode detection capability has been proposed. By simply adjusting the gate voltage and UV illumination, this sensor enables both real‐time detection and accumulation‐based sensing of toxic gases within a single device, providing a compact and adaptable platform for environmental monitoring ...
Jaewon Shin, Young‐Woo Jang, Seung‐Han Kang, Jeong‐Wan Jo, Jong Wook Shin, Yong‐Hoon Kim, Sung Kyu Park, Sung Woon Cho   +7 more
wiley   +1 more source