Results 31 to 40 of about 903,463 (268)
AKT activation controls cell survival in response to HDAC6 inhibition. [PDF]
HDAC6 is emerging as an important therapeutic target for cancer. We investigated mechanisms responsible for survival of tumor cells treated with a HDAC6 inhibitor.
Aboagye, EO +3 more
core +1 more source
This study aims to predict the causal relationships between management leadership, total quality management practices, and quality performance. Data is collected from a survey through the distribution of questionnaires.
Kurniawan Tjakrawala, Nurainun Bangun
doaj +1 more source
Combined Treatment with MEK and mTOR Inhibitors is Effective in In Vitro and In Vivo Models of Hepatocellular Carcinoma. [PDF]
Background: Hepatocellular carcinoma (HCC) is the most common primary liver cancer histotype, characterized by high biological aggressiveness and scarce treatment options.
Calvisi, Diego F +14 more
core +1 more source
Programmed death ligand 1 (PD-L1) is overexpressed in the most aggressive breast cancer subtype, triple-negative breast cancer (TNBC), assisting the eradication of antitumor immunity, and thereby enhancing the survival of the tumor.
Prachya Kongtawelert +4 more
doaj +1 more source
Introduction: The purpose of this study was to analyze the expression status, reciprocal interplay, and prognostic significance of AKT1 and hypoxia-inducible factor 1 alpha (HIF-1α) in AKT/mechanistic target of the rapamycin pathway and to enable them to
Ritesh Satardey +3 more
doaj +1 more source
PERBANDINGAN EARLY WARNING SYSTEMS (EWS) UNTUK MEMPREDIKSI KEBANGKRUTAN BANK UMUM DI INDONESIA
This research is testing the capability of several forewarning system models to predict bank bankruptcy. We apply these models on Indonesian commercial bank data during the period of 1994/ 1995 - 1999/2000.
Liza Angelina, SE, Msi, Akt
doaj +1 more source
Phosphorylation by Akt within the ST loop of AMPK-α1 down-regulates its activation in tumour cells [PDF]
The insulin/IGF-1 (insulin-like growth factor 1)-activated protein kinase Akt (also known as protein kinase B) phosphorylates Ser(487) in the ‘ST loop’ (serine/threonine-rich loop) within the C-terminal domain of AMPK-α1 (AMP-activated protein kinase-α1),
Chen +53 more
core +4 more sources
Chern Classes and Compatible Power Operations in Inertial K-theory
Let [X/G] be a smooth Deligne-Mumford quotient stack. In a previous paper the authors constructed a class of exotic products called inertial products on K(I[X/G]), the Grothendieck group of vector bundles on the inertia stack I[X/G].
Edidin, Dan +2 more
core +1 more source
Despite many advantages may be oered including architectural expertise in the design and delivery of industrial buildings and power plants, in recent times it has generally been excluded from this process, probably because of the lack of cleoles for ...
Hanif Kara +2 more
doaj +1 more source
Akt-dependent Pp2a activity is required for epidermal barrier formation during late embryonic development [PDF]
Acquisition of epidermal barrier function occurs late in mouse gestation. Several days before birth a wave of barrier acquisition sweeps across murine fetal skin, converging on dorsal and ventral midlines.
Byrne, C +3 more
core +2 more sources

