Nanoscopic Mapping of the Extracellular Space in Amyloid Plaque‐rich Cortex
The extracellular space and diffusion around amyloid plaques are examined using shadow imaging and single‐particle tracking. Increased diffusivity is found near plaques, extracellular matrix alterations, and plaque core penetrability that varies with amyloid phenotype.
Juan Estaún‐Panzano +11 more
wiley +1 more source
Real-World Data of Light Chain (AL) Amyloidosis: Prognostic Indices and Treatment Patterns. [PDF]
Mitrovic M +11 more
europepmc +1 more source
Presenting features, treatment patterns and predictors of outcomes in AL amyloidosis at a tertirary care cancer centre [PDF]
Aditya Nair +22 more
openalex +1 more source
Abstract INTRODUCTION In Alzheimer's disease (AD), females have higher prevalence and faster progression, but sex‐specific molecular findings in AD are limited. METHODS We comprehensively examined 6162 proteins in cerebrospinal fluid (CSF) from 2496 participants to identify sex‐specific proteomic alteration by CSF amyloid beta (Aβ)42 and phosphorylated
Anh N. Do +17 more
wiley +1 more source
Kinetics of hematologic response in AL amyloidosis: Insights from clinical and cytogenetic subgroup analysis in the daratumumab era. [PDF]
Bazarbachi AH +20 more
europepmc +1 more source
Kidney Carbuncle in a Patient with Primary Systemic Al-Amyloidosis and Nephortic Syndrome
Amina M. Alieva +6 more
openalex +2 more sources
Defining patient‐centered amyloid PET thresholds for the onset of tauopathy in Alzheimer's disease
Abstract INTRODUCTION Amyloid‐induced tauopathy drives clinical decline in Alzheimer's disease (AD). Because age and sex shape tau trajectories, defining patient‐centered amyloid thresholds for tauopathy onset could facilitate pre‐tauopathy AD identification and aid treatment decisions and prognosis.
Zeyu Zhu +21 more
wiley +1 more source
Frequency-adjusted daratumumab-based regimen versus bortezomib/dexamethasone in newly diagnosed AL amyloidosis: a matched-cohort study. [PDF]
Zheng W +6 more
europepmc +1 more source
Rotational Mechanics of the Left Ventricle in AL Amyloidosis
Maria Cristina Porciani +8 more
openalex +2 more sources
Multi‐omic expression of the VEGF family relates to Alzheimer's disease across diverse populations
Abstract INTRODUCTION The vascular endothelial growth factor (VEGF) signaling family plays a role in neurodegenerative diseases, including Alzheimer's disease (AD). Previous work has shown widespread effects of the members FLT1, FLT4, and VEGFB on AD outcomes. However, these analyses have focused within the non‐Hispanic White (NHW) population.
Julia B. Libby +23 more
wiley +1 more source

