Results 151 to 160 of about 17,175,483 (375)
A case report of hereditary apolipoprotein A-I amyloidosis associated with a novel APOA1 mutation and variable phenotype [PDF]
, 2016 Apolipoprotein A-I (apo A-I) amyloidosis is a non-AL, non-AA, and non-transthyretin type of amyloidosis associated with mutations in the APOA1 gene inherited in an autosomal dominant fashion. It is a form of systemic amyloidosis, but at presentation, can
Birn, H +6 more
core +1 more source
AL amyloidosis: advances in diagnostics and treatment.
Nephrology, Dialysis and Transplantation, 2018 AL amyloidosis (light chain; previously also called primary amyloidosis) is a systemic disease characterized by an amyloid deposition process affecting many organs, and which still has unsatisfactory survival of patients.
R. Ryšavá
semanticscholar +1 more source
ESC Heart Failure, EarlyView.This systematic review identified 24 clinical trials of medical device and surgical interventions for HFpEF, with 16 demonstrating at least safety and feasibility, but little evidence of long‐term benefit. Phenotype‐based responses suggest that certain interventions may benefit specific HFpEF subgroups, yet most trials suffered from heterogeneous ...
Kurdo Araz +5 more
wiley +1 more source
Dose-Intensive Melphalan With Blood Stem-Cell Support for the Treatment of AL (Amyloid Light-Chain) Amyloidosis: Survival and Responses in 25 Patients [PDF]
, 1998 Raymond L. Comenzo +13 more
openalex +1 more source
ESC Heart Failure, EarlyView.Abstract In the 2021 European Society of Cardiology (ESC) heart failure (HF) guidelines, sodium–glucose cotransporter 2 (SGLT2) inhibitors were recommended for the prevention of HF in patients with type 2 diabetes mellitus (T2DM) and for the treatment of HF with reduced ejection fraction (HFrEF).
Marco Metra +25 more
wiley +1 more source
Bilateral Chronic Subdural Nontraumatic Hematoma in a Woman Affected by AL Amyloidosis
Journal of Neurological Surgery Reports, 2015 Chronic subdural hematoma (CSDH) is a condition frequently seen in neurosurgical practice, especially among the elderly. It is often preceded by head injury, even a trivial trauma. Light chain (AL) amyloidosis is a disorder involving extracellular tissue
M. Luongo, M. Grassi, U. Godano
doaj +1 more source
ESC Heart Failure, EarlyView.Abstract Aims Renal impairment frequently coexists with heart failure (HF) and is associated with increased risk of poor clinical outcomes. This highlights the urgent need for therapies targeting both cardiac and renal dysfunction. AZD3427, a long‐acting recombinant fusion protein and relaxin analogue that selectively activates the relaxin family ...
Marcin Ufnal +9 more
wiley +1 more source
Structural relationship of κ-type light chains with AL amyloidosis: multiple deletions found in a VκIV protein [PDF]
, 1999 M A Alim +7 more
openalex +1 more source
Anti-IL1 in patients with low penetrance mutations for autoinflammatory diseases: tuscany and sicilian case series from paediatric to adult age [PDF]
, 2017 Patients with low penetrance mutations for Autoinflammatory syndromes (AID) can have severe clinical manifestations, which require to be treated with biological drugs anti-IL-1.
Giovanni Corsello +4 more
core
ESC Heart Failure, EarlyView.The aim of our study was to develop a more accurate staging system for hereditary ATTR patients currently receiving specific treatment. A staging system was created using as criteria: GLS ≤ −11%, NT‐proBNP ≤ 2,000 ng/L, and eGFR ≤ 65 mL/min. We managed to accurately stratify patients into three disease stages, significantly different in terms of ...
Gabriela Neculae +7 more
wiley +1 more source