Results 191 to 200 of about 79,953 (279)
Single-cell and clonal analysis of AL amyloidosis plasma cells and their bone marrow microenvironment. [PDF]
Gort-Freitas NA +24 more
europepmc +1 more source
Molecular imprinting for neurology: Materials, applications, and limitations
Molecularly imprinted materials: diagnostic, therapeutic and research applications in neurology. Molecularly imprinted materials offer high specificity and affinity for target molecules in neurological applications. This review highlights their synthesis, characterisation, and use in diagnostics, research and therapeutics.
Xiaohan Ma +3 more
wiley +1 more source
Kinetics of hematologic response in AL amyloidosis: Insights from clinical and cytogenetic subgroup analysis in the daratumumab era. [PDF]
Bazarbachi AH +20 more
europepmc +1 more source
New Perspective: Bench to Bedside Evidence of the Role of CD8+ T Cells in Alzheimer's Disease
Emerging evidence highlights a previously underappreciated role of CD8+ T cells in Alzheimer's disease (AD). Beyond amyloid‐β and tau pathology, CD8+ T‐cell subsets infiltrate the central nervous system and exhibit functional heterogeneity. Cytotoxic effector CD8+ T cells may exacerbate neuroinflammation and neuronal injury, whereas regulatory or ...
Yong Peng +10 more
wiley +1 more source
Frequency-adjusted daratumumab-based regimen versus bortezomib/dexamethasone in newly diagnosed AL amyloidosis: a matched-cohort study. [PDF]
Zheng W +6 more
europepmc +1 more source
ABSTRACT Psoriasis is a chronic autoimmune disease characterized by systemic inflammation and skin involvement, affecting millions of individuals worldwide. However, few studies have evaluated whether psoriasis and cardiac magnetic resonance imaging (CMR) traits share a common genetic basis.
Junlin Yang +8 more
wiley +1 more source
RNA‐Based Therapies for Inherited Metabolic Disorders
ABSTRACT Inherited metabolic disorders (IMDs) are a diverse and complex group of genetic conditions resulting from deficiencies in enzymes, transporters, or cofactors. These deficiencies lead to metabolic dysfunction and severe clinical consequences. Despite significant progress in understanding their molecular basis, treatment options remain limited ...
Reddy Sreekanth Vootukuri +5 more
wiley +1 more source
Molecular Expression Differences in Specific Blood Mononuclear Cell-Types Identify Patients With AL Amyloidosis. [PDF]
Kaplan D +11 more
europepmc +1 more source
Structured graphical abstract‐text element Key Question It remains unclear whether patients with heart failure with preserved ejection fraction (HFpEF) in different phenotypes also have various clinical outcomes. Key Finding Significant differences existed in baseline characteristics and outcomes among different phenotypes; patients with HFpEF‐3 (right
Shuai Yuan +14 more
wiley +1 more source

